Corpus overview


MeSH Disease

Human Phenotype

Fever (56)

Cough (43)

Pneumonia (15)

Fatigue (15)

Dyspnea (14)


    displaying 21 - 30 records in total 56
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    Comparison of the Clinical Characteristics of Patients With COVID-19 in Suining and Wuhan

    Authors: Xiao-juan Wu; Chao-Ping Wang; Xiao-Bin Luo; Gao-Yan He; Bao-Lin Jia; Jing Wang; Li Luo; Rong Qiu; Zheng-Guang He; Min-Chao Li

    doi:10.21203/ Date: 2020-05-30 Source: ResearchSquare

     Background Coronavirus disease MESHD 2019 (COVID-19), caused by severe acute respiratory syndrome MESHD coronavirus 2 (SARS-CoV-2), which was first identified in December 2019 in Wuhan. This study mainly analyzed the clinical characteristics, imaging features, and prognosis of patients with COVID-19 in Suining, one of China's fourth-tier cities, and Wuhan in 2019 and compared data between the 2 cities. Methods A retrospective analysis of the epidemiological history, clinical data, symptom presentation, laboratory test results, chest computed tomography (CT) imaging features, treatment measures and prognosis of 68 patients with COVID-19 diagnosed at Wuhan Red Cross Hospital and 17 patients with COVID-19 diagnosed at Suining Central Hospital from January 23, 2020, to February 27, 2020, was conducted. Results 1) The incidence rate of COVID-19 in Wuhan was 52.99‱, and the incidence rate in Suining was 0.04‱. The median age TRANS of patients with COVID-19 was 40.71 years old in Suining and 56.04 years old in Wuhan. The age TRANS of patients with COVID-19 in Wuhan was significantly older than that of patients with COVID-19 in Suining. Among the 68 patients with COVID-19 in Wuhan, 30 (44.1%) had hypertension MESHD hypertension HP, and 25 (36.8%) had diabetes. Three out of the 17 patients in Suining (17.6%) had hypertension MESHD hypertension HP, and 2 patients (11.8%) had diabetes. The proportion of patients with diabetes or hypertension MESHD hypertension HP in Wuhan was significantly higher than that in Suining (P<0.05). In the clinical classification, there were 1 (5.9%) and 23 (33.8%) patients with severe COVID-19 in Suining and Wuhan, respectively. The proportion of patients with severe COVID-19 in Wuhan was significantly higher than that in Suining (P<0.05). Fever MESHD Fever HP and cough MESHD cough HP were the most common clinical symptoms, with 9 cases (52.9%) and 8 cases (47.1%) in Suining, respectively, and 54 cases (79.4%) and 42 cases (61.8%) in Wuhan, respectively. There was 1 patient (5.9%) with COVID-19 with dyspnea MESHD dyspnea HP in Suining and 23 patients (33.8%) with COVID-19 with dyspnea MESHD dyspnea HP in Wuhan; the difference was statistically significant (P<0.05). Chest CT showed that lung consolidation occurred in 2 (11.8%) and 26 (38.2%) patients with COVID-19 in Suining and Wuhan, respectively. The proportion of lung consolidation in patients in Wuhan was significantly higher than that in patients in Suining (P<0.05). The laboratory tests suggested that percentage ofelevated C-reactive protein (CRP) (58.8%), ALT (33.8%), blood SERO glucose (45.6%), creatine kinase (CK) (33.8%) or D-dimer (47.1%) of patients in Wuhan were significantly increased than those in Suining (29.4%, 5.9%, 17.6%, 5.9%, and 17.7%, respectively). Moreover, the average length of hospital stay of patients in Wuhan was 17.49 days, which was significantly longer than that of patients in Suining (12.29 days). Conclusions The incidence of COVID-19 in fourth-tier cities, Suining, in China was significantly lower than that in Wuhan, and the disease MESHD severity was generally lower than that in Wuhan, with mostly good prognoses. Advanced age TRANS, diabetes, and hypertension MESHD hypertension HP are important factors that aggravate COVID-19, while elevated CRP, ALT, blood SERO glucose, CK, and D-dimer levels are important indicators for severe disease MESHD

    Analysis of moderate and severe cases of novel coronavirus disease MESHD (COVID-19) versus influenza A (H1N1)

    Authors: Weishun Hou; Haoyu Sheng; Manman Liang; zijian Wang; Xiuliang Xu; Yusheng Cheng; Fang Liu; Aiping Zhang; Bin Quan; Yunfeng Zhou; Jianghua Yang

    doi:10.21203/ Date: 2020-05-26 Source: ResearchSquare

    Background To analyse the clinical characteristics, laboratory tests, and imaging findings of severe cases of coronavirus disease MESHD 2019 (COVID-19) versus severe cases of influenza A (H1N1).Methods We retrospectively analysed the clinical data of moderate and severe COVID-19 and H1N1 cases between January 23 and February 23, 2020.Results A total of 33 COVID-19 cases had a clear history of exposure to severe acute respiratory syndrome MESHD coronavirus 2 (SARS-CoV-2), with an incubation period TRANS of 11.12 ± 7.47 days. A total of 29 H1N1 cases were included in this study. Most cases were sporadic, with an incubation period TRANS of 3.67 ± 0.82 days (P = 0.002). The age TRANS at onset was 19.79 ± 23.88 years for H1N1 and 43.48 ± 17.82 years for COVID-19 (P < 0.001). For H1N1, common clinical symptoms were high fever MESHD fever HP and myalgia MESHD myalgia HP. The time of disease progression MESHD from moderate to severe was 13.60 ± 5.64 days for COVID-19 and 5.25 ± 2.36 days for H1N1 (P = 0.035). Laboratory tests showed that white blood SERO cells (WBC), neutrophils (N), lactate dehydrogenase (LDH), C-reactive protein (CPR), and procalcitonin (PCT) were significantly higher in severe H1N1 cases than in severe COVID-19 cases. D-dimer (DD) was 1.43 ± 1.19 µg/mL in the COVID-19 group, which was higher than that in the H1N1 group (0.88 ± 0.32 µg/mL, P = 0.013). High-resolution computed tomography (CT) showed severe COVID-19 cases presented mainly interstitial involvement, shown by large ground-glass opacities, whereas severe H1N1 cases presented both interstitial and parenchymal involvement, especially parenchymal involvement. All the COVID-19 patients survived to discharge, and one H1N1 patient died.Conclusion Compared with H1N1 patients, COVID-19 patients had a clear history of exposure to SARS-CoV-2, were older, presented milder clinical symptoms and a slower progression, and rarely had bacterial infections MESHD. Most H1N1 patients had sporadic H1N1 with an acute onset, high fever MESHD fever HP, and rapid progression; secondary bacterial infection MESHD was an important cause of disease MESHD aggravation.

    Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery

    Authors: Louise Ronnje; John-Kalle Länsberg; Olga Vikhareva; Stefan Hansson; Andreas Herbst; Mehreen Zaigham

    doi:10.21203/ Date: 2020-05-25 Source: ResearchSquare

    BackgroundIt has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From the few case series that are available in the literature, women with high risk pregnancies have been associated with higher morbidity. It has been suggested that pregnancy induced immune responses and cardio-vascular changes can exaggerate the course of the COVID-19 infectionCase presentationA 26-year old Somalian woman (G2P1) presented with a nine-day history of shortness of breath, dry cough MESHD cough HP, myalgia MESHD myalgia HP, nausea MESHD nausea HP, abdominal pain MESHD abdominal pain HP and fever MESHD fever HP. A nasopharyngeal swab returned positive for severe acute respiratory syndrome MESHD coronavirus 2 (SARS-CoV-2) infection MESHD. Her condition rapidly worsened leading to severe liver and coagulation impairment. An emergency MESHD Caesarean section was performed at gestational week 32+6 after which the patient made a rapid recovery. Severe COVID-19 promptly improved by the termination of the pregnancy or atypical HELLP ( Hemolysis MESHD, Elevated Liver Enzymes and Low Platelet Count) exacerbated by concomitant COVID-19 infection MESHD could not be ruled out. There was no evidence of vertical transmission TRANS. ConclusionThis case adds to the growing body of evidence which raises concerns about the possible negative maternal outcomes of COVID-19 infection MESHD during pregnancy and advocates for pregnant women to be recognized as a vulnerable group during the current pandemic.

    Clinical features of COVID-19 patients in one designated medical institutions in Chengdu, China

    Authors: Gui Zhou; Yun-Hui Tan; Jiang-Cuo Luo; Yi-Xiao Lu; Jing Feng; Juan Li; Yun-Mei Yang; Long Chen; Jian-Ping Zhang

    doi:10.21203/ Date: 2020-05-19 Source: ResearchSquare

    OBJECTIVE: To study the clinical characteristics of patients infected with the 2019 severe acute respiratory syndrome MESHD coronavirus 2 (SARS-Cov-2) responsible for coronavirus disease MESHD (COVID-2019).METHODS: Data were collected from 20 patients admitted to the Pidu District People’s Hospital in Chengdu from January 26, 2020 to March 1, 2020 with laboratory-confirmed SARS-Cov-2 infection MESHD. Clinical data were collected using the World Health Organization (WHO) nCoV CASE RECORDFORM Version 1.2 28JAN2020, which includes parameters such as: temperature, epidemiological characteristics, social network, history of exposure, and incubation period TRANS. If information was unclear, the team reviewed the original data and contacted TRANS patients directly if necessary.RESULTS: The median age TRANS of the 20 COVID-19 infected patients studied was 42.5 years. In this cohort, four patients became severely ill and one deteriorated rapidly during treatment. This patient was transferred to another medical center with an intensive care unit (ICU) for treatment. This patient died after admission to the ICU. Two of the twenty patients remained positive SARS-Cov-2 more than three weeks, and they were quarantined in a medical facility without medication. According to our analysis, all of the studied cases were infected by human-to-human transmission TRANS due to the lack of protective measures; transmission TRANS through contact within families requires confirmation. The most common symptoms at onset TRANS of illness were fever MESHD fever HP in 13 (65%) patients, cough MESHD cough HP in 9 (45%), headache MESHD headache HP in 3 (15%), fatigue MESHD fatigue HP in 6 (30%), diarrhea MESHD diarrhea HP in 3 (15%), and abdominal pain MESHD abdominal pain HP in 2 (10%). Six patients (30%) developed shortness of breath upon admission. The median time from exposure to onset of illness was6.5 days (interquartile range 3.25–9 days), and from the onset of symptoms TRANS to first hospital admission was 3.5 (1.25–7) days.CONCLUSION: Compared with patients infected with SARS-Cov-2 in Wuhan (up to the end of February 2020), the symptoms of patients in one hospital in Chengdu, Sichuan Province, were relatively mild and patients were discharged from the hospital after only a short stay. However, the fasting blood SERO glucose of the infected individuals was found to be slightly elevated because of the state of emergency MESHD. The dynamic changes in lymphocyte levels can predict disease MESHD status of COVID-19. They are also suggestive of changes in mean platelet volume during disease progression MESHD. This suggests that the patients had mild cases of COVID-19. However, because there is no effective drug treatment for COVID-19, it is important to detect and identify severe cases from mild cases early.

    REMBRANDT: A high-throughput barcoded sequencing approach for COVID-19 screening.

    Authors: Dario Palmieri; Jalal K Siddiqui; Anne Gardner; Richard Fishel; Wayne Miles

    doi:10.1101/2020.05.16.099747 Date: 2020-05-17 Source: bioRxiv

    The Severe Acute Respiratory Syndrome MESHD Coronavirus-2 (SARS-CoV-2), also known as 2019 novel coronavirus (2019-nCoV), is a highly infectious RNA virus. A still-debated percentage of patients develop coronavirus disease MESHD 2019 (COVID-19) after infection MESHD, whose symptoms include fever MESHD fever HP, cough MESHD cough HP, shortness of breath and fatigue MESHD fatigue HP. Acute and life-threatening respiratory symptoms are experienced by 10-20% of symptomatic patients, particularly those with underlying medical conditions that includes diabetes, COPD and pregnancy. One of the main challenges in the containment of COVID-19 is the identification and isolation of asymptomatic TRANS/pre-symptomatic individuals. As communities re-open, large numbers of people will need to be tested and contact-tracing TRANS of positive patients will be required to prevent additional waves of infections MESHD and enable the continuous monitoring of the viral loads COVID-19 positive patients. A number of molecular assays are currently in clinical use to detect SARS-CoV-2. Many of them can accurately test hundreds or even thousands of patients every day. However, there are presently no testing platforms that enable more than 10,000 tests per day. Here, we describe the foundation for the REcombinase Mediated BaRcoding and AmplificatioN Diagnostic Tool (REMBRANDT), a high-throughput Next Generation Sequencing-based approach for the simultaneous screening of over 100,000 samples per day. The REMBRANDT protocol includes direct two-barcoded amplification of SARS-CoV-2 and control amplicons using an isothermal reaction, and the downstream library preparation for Illumina sequencing and bioinformatics analysis. This protocol represents a potentially powerful approach for community screening, a major bottleneck for testing samples from a large patient population for COVID-19.

    Impact of COVID-19 infection MESHD on maternal and neonatal outcomes: a review of 287 pregnancies

    Authors: Fatemeh Azarkish; Roksana Janghorban

    doi:10.1101/2020.05.09.20096842 Date: 2020-05-15 Source: medRxiv

    Pregnant women are vulnerable group in viral outbreaks especially in the severe acute respiratory syndrome MESHD coronavirus 2 (SARS-CoV-2) pandemic. The aim of this review was to identify maternal and neonatal outcomes in available articles on pregnancies affected by COVID-19. The articles that had assessed outcomes of pregnancy and perinatal of women with COVID-19 between Oct 2019 and Apr 30, 2020 without language limitation were considered. All kinds of studies such as case report, case series, retrospective cohort, case control were included. We searched databases, selected relevant studies and extracted data regarding maternal and neonatal outcomes from each article. Data of 287 pregnant women with COVID-19 of 6 countries were assessed from 28 articles between December 8, 2019 and April 6, 2020. Most pregnant women reported in their third trimester, 102 (35.5%) cases were symptomatic at the time of admission. Common onset symptoms TRANS, abnormal laboratory findings, and chest computed tomography pattern were fever MESHD fever HP (51.5%), lymphocytopenia (67.9%), and multiple ground-glass opacities (78.5%) respectively. 93% of all deliveries were done through cesarean section. No maternal mortality and 3 % ICU admission were reported. Vertical transmission TRANS was not reported but its possibility was suggested in three neonates. One neonatal death MESHD, one stillbirth MESHD, and one abortion were reported. All newborns were not breastfed. This review showed fewer adverse maternal and neonatal outcomes in pregnant women with COVID-19 in comparison with previous coronavirus outbreak infection MESHD in pregnancy. Limited data are available regarding possibility of virus transmission TRANS in utero, during vaginal childbirth and breastfeeding. Effect of COVID-19 on first and second trimester and ongoing pregnancy outcomes in infected mothers is still questionable.

    Epidemiological,clinical and radiological findings in medical staff with COVID-19 in Wuhan, China: a single-centered, retrospective cohort study

    Authors: Jie Liu; Liu Ouyang; Pi Guo; Haisheng Wu; Peng Fu; Yuliang Chen; Dan Yang; Xiaoyu Han; Yukun Cao; Osamah Alwalid; Hanping Wu; Heshui Shi; Fan Yang; Yu Hu; Chuansheng Zheng

    doi:10.21203/ Date: 2020-05-14 Source: ResearchSquare

    Backgrounds In December 2019, a pneumonia MESHD pneumonia HP associated with the severe acute respiratory syndrome MESHD coronavirus 2 (SARS-Cov-2) emerged in Wuhan city, China. As of 20 Feb 2020, a total of 2,055 medical staff infected with SARS-Cov-2 in China had been reported. The predominant cause of the infection MESHD and the failure of protection among medical staff remains unclear. We sought to explore the epidemiological, clinical characteristics and prognosis of novel coronavirus-infected medical staff.Methods Medical staff who infected with SARS-Cov-2 and admitted to Union Hospital, Wuhan between 16 Jan, 2020 to 25 Feb, 2020 were included retrospectively. Epidemiological, clinical and radiological data were compared by occupation and analyzed with the Kaplan-Meier and Cox regression methods.Results A total of 101 medical staff (32 males TRANS and 69 females TRANS; median age TRANS: 33 years old) were included in this study and 74% were nurses. None had an exposure to Huanan seafood wholesale market or wildlife. A small proportion of the cohort had contact with specimens (3%) as well as patients infected with SARS-Cov-2 in fever MESHD fever HP clinics (15%) and isolation wards (3%). 80% of medical staff showed abnormal IL-6 levels and 33% had lymphocytopenia. Chest CT mainly manifested as bilateral (62%), septal/subpleural (77%) and ground­glass opacities (48%). The major differences between doctors and nurses manifested in laboratory indicators. As of the last observed date, no patient was transferred to intensive care unit or died, and 98 (97%) had been discharged. Fever MESHD Fever HP (HR=0.57; 95% CI 0.36-0.90) and IL-6 levels greater than >2.9 pg/ml (HR=0.50; 95% CI 0.30-0.86) on admission were unfavorable factors for discharge.Conclusions Our findings suggested that the infection MESHD of medical staff mainly occurred at the early stages of SARS-CoV-2 epidemic in Wuhan, and only a small proportion of infection MESHD had an exact mode. Meanwhile, medical staff infected with COVID-19 have relatively milder symptoms and favorable clinical course than other ordinary patients, which may be partly due to their medical expertise, younger age TRANS and less underlying diseases MESHD. The potential risk factors of presence of fever MESHD fever HP and IL-6 levels greater than >2.9 pg/ml could help to identify medical staff with poor prognosis at an early stage.

    On the Front (Phone) Lines: Results of a COVID-19 Hotline in Northeast Ohio

    Authors: David Margolius; Mary Hennekes; Jimmy Yaho; Douglas Einstadter; Douglas Gunzler; Nabil Chehade; Ashwini R Sehgal; Yasir Tarabichi; Adam T Perzynski

    doi:10.1101/2020.05.08.20095745 Date: 2020-05-13 Source: medRxiv

    ABSTRACT Importance: Severe acute respiratory syndrome MESHD coronavirus (SARS-CoV-2) and the associated coronavirus disease MESHD of 2019 (COVID-19) have presented immense challenges for health care systems. Many regions have struggled to adapt to disruptions to health care practice and employ systems that effectively manage the demand for services. Objective: To examine the effectiveness of the first five weeks of a 24/7 physician-staffed COVID-19 hotline. Design: Cohort study using electronic health records. Setting: A single large health care system in Northeast Ohio. Participants: During 5 weeks of operation, 10,112 patients called the hotline (callers) and were evaluated by a registered nurse (RN) using standardized protocols. Of these, 4,213 (42%) were referred for a physician telehealth visit (telehealth patients). The mean age TRANS of callers was 42 years. 67% were female TRANS, 51% white, and 46% were on Medicaid or uninsured. Intervention: Physician telehealth visits for COVID-19. Main Outcomes and Measures: We describe clinical diagnosis, patient characteristics ( age TRANS, sex race/ethnicity, smoking status, insurance status), and visit disposition. We use logistic regression to evaluate associations between patient characteristics, visit disposition and subsequent emergency MESHD department use, hospitalization, and SARS-Cov-2 PCR testing. Results: Common caller concerns included cough MESHD cough HP, fever MESHD fever HP, and shortness of breath. Most telehealth patients (79%) were advised to self-isolate at home, 14% were determined to be unlikely to have COVID-19, 3% were advised to seek emergency MESHD care, and 4% had miscellaneous other dispositions. A total of 287 (7%) patients had a subsequent ED visit, and 44 (1%) were hospitalized with a COVID-19 diagnosis. Of the callers, 482 (5%) had a COVID-19 test reported with 69 (14%) testing positive. Among patients advised to stay at home, 83% had no further face-to-face visits. In multivariable results, only a physician recommendation to seek emergency MESHD care was associated with emergency MESHD room use (OR=4.73, 95%CI 1.37-16.39, p=.014). Only older age TRANS was associated with having a positive test result. Conclusions and Relevance: Robust, physician-directed telehealth services can meet a wide range of needs during the acute phase of a pandemic, conserving scarce resources such as personal protective equipment and testing supplies and preventing the spread of infections MESHD to patients and health care workers.

    Facemasks prevent influenza-like illness: implications for COVID-19

    Authors: Jie Wei; Michael Doherty; Monica S.M. Persson; Subhashisa Swain; Changfu Kuo; CHAO ZENG; guanghua Lei; Weiya Zhang

    doi:10.1101/2020.05.07.20094912 Date: 2020-05-12 Source: medRxiv

    The coronavirus disease MESHD 2019 (COVID-19) pandemic is causing a huge toll on individuals, families, communities and societies across the world. Currently, whether wearing facemasks in public should be a measure to prevent transmission TRANS of severe acute respiratory syndrome MESHD coronavirus-2 (SARS-CoV-2) remains contraversial.1 This is largely because there have been no randomized controlled trials (RCTs) for coronavirus to directly support this. However, lessons may be taken from published RCTs examining influenza-like illness (ILI).2,3 Recent studies suggested that SARS-CoV-2 shares similar transmission TRANS route with influenza virus,4 and the incidence of community transmission TRANS of SARS-CoV-2 in individuals with ILI is high.5 Therefore, we undertook this meta-analysis of RCTs examining the efficacy of wearing facemasks to prevent ILI in community settings, irrespective of confirmatory testing for the causative virus. We undertook a systematic literature search for RCTs related to facemasks and ILI between 1966 and April 2020 using PUBMED, EMBASE, and Cochrane library. RCTs undertaken in community (not hospital) settings comparing wearing and not wearing facemasks for ILI were included. Incidence of ILI (e.g., fever MESHD fever HP, cough MESHD cough HP, headache MESHD headache HP, sore throat, aches or pains MESHD pains HP in muscles or joints) was estimated per group. Relative risk (RR) and 95% confidence interval (CI) were calculated. We screened 899 related abstracts and eventually included 8 RCTs (Figure S1). Basic characteristics and quality of included RCTs are listed in Supplement. Participants wearing facemasks had a significantly lower risk of developing ILI than those not wearing facemasks (pooled RR=0.81, 95% CI: 0.70-0.95) and there was no heterogeneity (Figure 1). The decreased risk of ILI was more pronounced if everyone wore facemask irrespective of whether they were infected or not (RR=0.77, 95% CI: 0.65-0.91), compared to those wearing facemasks when infected (RR=0.95, 95% CI: 0.58-1.56) or uninfected (RR=1.26, 95% CI: 0.69-2.31). This study shows that wearing facemasks, irrespective of infection MESHD status, is effective in preventing ILI spread in the community. This situation mirrors what is happening now in public settings where we do not know who has been infected and who has not. Although there are no RCTs of facemasks for SARS-CoV-2, as with other simple measures such as social distancing and handwashing, these data support the recommendation to wear facemasks in public to further reduce transmission TRANS of SARS-CoV-2 and flatten the curve of this pandemic, especially when social distancing is impractical, such as shopping, or travelling TRANS with public transport for work that cannot be done from home.

    COVID-19 Infection MESHD Manifesting as a Severe Gastroparesis MESHD Gastroparesis HP Flare: A Case Report

    Authors: Jun Song; MD; Rajiv Bhuta; MD; Kamal Baig; MD; Henry P. Parkman; MD; Zubair Malik; MD

    doi:10.21203/ Date: 2020-05-11 Source: ResearchSquare

    Background: Coronavirus Disease MESHD 2019 (COVID-19) is a disease MESHD caused by infection MESHD infection with Severe HP with Severe Acute Respiratory Syndrome MESHD Coronavirus 2 (SARS-CoV-2), which commonly presents with symptoms including fever MESHD fever HP, cough MESHD cough HP, and dyspnea MESHD dyspnea HP. More recently, however, some patients have tested positive for COVID-19 after developing gastrointestinal (GI) symptoms either solely or in conjunction with respiratory symptoms. This may be due to SARS-CoV-2 infection MESHD of the GI tract. In patients with chronic GI illnesses, COVID-19 may initially present as a flare of their underlying GI conditions as viruses have historically been implicated in exacerbations of GI disorders, including gastroparesis MESHD gastroparesis HP. Case presentation: We report a case of a 37 year-old female TRANS with a history of diabetic gastroparesis MESHD gastroparesis HP who presented to the Emergency MESHD Department (ED) in a gastroparesis MESHD gastroparesis HP flare. Her symptoms in the ED failed to improve with fluids and anti-emetic medications. After developing a fever MESHD fever HP, she was tested and found to be positive for COVID-19.Conclusion: To our knowledge, at the present time, this is the first report of a patient with COVID-19 presenting with signs and symptoms MESHD of a gastroparesis MESHD gastroparesis HP flare. This case illustrates that patients with underlying GI disorders, such as gastroparesis MESHD gastroparesis HP, may have SARS-CoV-2 infections MESHD that present as an exacerbation of their underlying disorder. Initial presentation of these patients manifesting as a flare of their chronic GI disease MESHD, more severe than usual, should prompt an index of suspicion for COVID-19.

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MeSH Disease
Human Phenotype

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