Corpus overview


Overview

MeSH Disease

Transmission

gender (1)


Seroprevalence

There are no seroprevalence terms in the subcorpus

    displaying 1 - 1 records in total 1
    records per page




    COVID-19 MESHD-Related Abnormal Liver Enzymes Levels: A Retrospective Study

    Authors: Jian-dan Qian; Yan Wang; Tian-tian Yao; Hai-chao Li; gui-qiang Wang

    doi:10.21203/rs.3.rs-36830/v1 Date: 2020-06-19 Source: ResearchSquare

    Background: A new disease called Coronavirus disease MESHD ( COVID-19 MESHD) related to SARS-CoV-2 has brought serious attacks to the world. It causes damage to multiple organ systems of the body include liver. Here we intend to shed light on the clinical features its mechanism related to liver damage which caused by COVID-19 MESHD.Methods: Clinical records and laboratory results were obtained from 138 patients with laboratory-confirmed COVID-19 MESHD who were admitted to Tongji hospital, Wuhan, China from February 8, 2020 to February 18, 2020. Information on clinical features of patients with abnormal liver tests were collected for analysis.Results: Fifty-four (39.1%) and eighty-three (60.1%) patients had abnormal liver enzyme levels on admission and during the course of disease. Hepatocyte type was more common than cholestatic type abnormal MESHD. 24(17.4%) patients reached the liver injury MESHD standard in the course of disease. Patients with abnormal liver enzyme levels were more likely to be male TRANS, had higher levels of inflammation MESHD indicators, lower pulse oxygen saturation and lymphocyte count. There is a significantly higher proportion of abnormal liver enzymes levels in the patients which administrated antibiotics during hospitalization, compared with that in the ones without antibiotics therapy (56.6% vs 32.7%). Patients with liver injury MESHD was an independent predictor of a poor prognosis (p<0.0001, OR 7.774, 95%CI 2.674-22.599).Conclusions: Liver injury MESHD in COVID-19 MESHD patients was an independent predictor of a poor prognosis. The COVID-19 MESHD-related abnormal liver enzymes levels may be considered as the result of secondary liver damage caused mainly by several factors. Hypoxia MESHD and disease severity account for the largest proportion.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).
The web page can also be accessed via API.

Sources


Annotations

All
None
MeSH Disease
Transmission
Seroprevalence


Export subcorpus as...

This service is developed in the project nfdi4health task force covid-19 which is a part of nfdi4health.

nfdi4health is one of the funded consortia of the National Research Data Infrastructure programme of the DFG.