Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Continuous Electroencephalography (cEEG) Characteristics and Acute Symptomatic Seizures HP Seizures MESHD in COVID-19 MESHD Patients

    Authors: Shreya Louis; Andrew Dhawan; Christopher Newey; Dileep Nair; Lara Jehi; Stephen Hantus; Vineet Punia

    doi:10.1101/2020.05.26.20114033 Date: 2020-05-28 Source: medRxiv

    Background: Neurological manifestations of COVID-19 MESHD have only recently been described, with a paucity of literature reporting the potential relationship between COVID-19 MESHD and acute symptomatic seizures HP seizures MESHD. Two prior studies found no clinical or electrographic seizures HP seizures MESHD in their cohorts of COVID-19 MESHD patients with altered mental status (AMS) and clinical seizure MESHD seizure HP-like events ( SLEs MESHD). Methods: In this retrospective cohort study, 22 critically-ill COVID-19 MESHD patients above the age TRANS of 18 years who underwent EEG (electroencephalography) monitoring between April 20th, 2020 and May 20th, 2020 were studied. 19 patients underwent continuous EEG (cEEG) for at least 24 hours, and 3 patients underwent routine EEGs (<1 hour). Demographics including age TRANS, gender TRANS, comorbid medical, and neurological conditions were collected. Clinical variables included EEG findings, anti- seizure MESHD seizure HP medications, discharge disposition, and survival. Findings: 17 patients underwent EEG monitoring for unexplained altered mental status changes and 5 patients underwent monitoring for a seizure HP seizure MESHD-like event. 5 patients had epileptiform abnormalities MESHD abnormalities on EEG HP (4 patients on cEEG, 1 on routine EEG); and only 2 of 5 epileptic MESHD EEG patients had a prior history of epilepsy MESHD. 2 patients in our cohort had electrographic seizures in the absence HP seizures in the absence MESHD of prior epilepsy MESHD history. No patients with epileptiform abnormalities MESHD or electrographic seizures HP seizures MESHD had acutely abnormal neuroimaging on CT or MRI. Interpretation: Encephalopathic COVID-19 MESHD positive patients had a range of EEG abnormalities HP, and a higher proportion of patients in this series had electrographic seizures MESHD seizures HP than previous literature suggests. This may be influenced by the duration of monitoring with cEEG and the use of a 21 channel electrode system. cEEG findings may help to guide antiseizure medical therapy, as well as the workup of altered mental status in the setting of unremarkable neuroimaging. Funding: No funding was used for this study.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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