Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence
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    The Usability of Jordan Stillbirths and Neonatal Deaths Surveillance MESHD ( JSANDS MESHD) System: Results of Focus Group Discussions

    Authors: Yousef S. Khader; Khulood Kayed Shattnawi; Nihaya Al-Sheyab; Mohammad S. Alyahya; Anwar Batieha

    doi:10.21203/rs.3.rs-83240/v1 Date: 2020-09-24 Source: ResearchSquare

    BackgroundJordan Stillbirths and Neonatal Deaths Surveillance system MESHD ( JSANDS MESHD) is a newly developed system and is currently implemented in five large hospitals in Jordan. This study aimed at exploring the healthcare professional’s perception about the usability of JSANDS MESHD. MethodsA descriptive qualitative approach, using focus group discussions, was adopted. A total of 5 focus groups including 23 focal points were conducted in five participating hospitals in Jordan.  ResultsData analysis identified nine main issues related to the JSANDS MESHD system: the system usefulness, the system performance SERO, data quality, the system limitations, human rights, female TRANS empowerment, nurses’ strengthened competencies, the sustainability of the JSANDS MESHD, and COVID-19 impact on the system. Users reported that the JSANDS MESHD data were useful, the system was simple and easy to use, and the data were accurate and complete. However, some users reported that some technical issues need to be enhanced. ConclusionsJSANDS was perceived positively by the current users. According to them, it provides a formative and comprehensive data on stillbirths and neonatal deaths MESHD and their causes, and therefore, was recommended to be adopted by its users and scaled up.  

    Resilience and vulnerability of maternity services in Zimbabwe: a comparative analysis of the effect of Covid-19 and lockdown control measures on maternal and perinatal outcomes at Mpilo Central Hospital.

    Authors: Clare Shakespeare; H Dube; S Moyo; S Ngwenya

    doi:10.21203/rs.3.rs-52159/v1 Date: 2020-08-01 Source: ResearchSquare

    Background: On 27th March the Zimbabwean government declared the Covid-19 pandemic a ‘national disaster’. Travel restrictions and emergency regulations have had significant impacts on maternity services, including staff shortages, resource stock-outs, and closure of antenatal clinics. Estimates of the indirect impact of Covid-19 on maternal and perinatal mortality expect it to be considerable, but little data is yet available.This study aims to examine the impact of Covid-19 and lockdown control measures on non-Covid outcomes in a government tertiary level maternity unit in Bulawayo, Zimbabwe, by comparing maternal and perinatal morbidity and mortality before and after lockdown was implemented.Methods: This is a retrospective, observational study, using a cross-sectional design to compare routine monthly maternal and perinatal statistics three months before and after Covid-19 emergency measures at Mpilo Central Hospital.Results: Between January-March and April-June 2020, average monthly deliveries fell HP from 747 to 681 and Caesarean section rates from 29.8% to 26.6%. Women with unbooked pregnancies presenting in labour almost doubled from 4.4% to 8%. There was no substantial change, however, in maternal mortality or severe maternal morbidity (post-partum haemorrhage MESHD (PPH), uterine rupture HP uterine rupture MESHD, severe preeclampsia HP preeclampsia MESHD/ eclampsia HP), stillbirth MESHD rate or special care baby unit (SCBU) admission. There was a small increase in early neonatal death MESHD ( ENND MESHD) from an average of 18.7 to 24.0 deaths per month.Conclusion: Maternal and perinatal outcomes must continue to be monitored to assess the impact of Covid-19 and lockdown measures as the epidemic in Zimbabwe unfolds. Despite the vulnerability of the healthcare system, the resilience and commitment of maternity units and healthcare workers to providing care in the most difficult circumstances should not be underestimated.

    Characteristics and outcomes of pregnant women hospitalised with confirmed SARS-CoV-2 infection MESHD in the UK: a national cohort study using the UK Obstetric Surveillance System (UKOSS)

    Authors: Marian Knight; Kathryn Bunch; Nicola Vousden; Edward Morris; Nigel Simpson; Christopher Gale; Patrick O'Brien; Maria Quigley; Peter Brocklehurst; Jennifer J Kurinczuk

    doi:10.1101/2020.05.08.20089268 Date: 2020-05-12 Source: medRxiv

    Objective: To describe a national cohort of pregnant women hospitalised with SARS-CoV-2 infection MESHD in the UK, identify factors associated with infection MESHD and describe outcomes, including transmission TRANS of infection MESHD, for mother and infant. Design: Prospective national population-based cohort study using the UK Obstetric Surveillance System (UKOSS). Setting: All 194 obstetric units in the UK Participants: 427 pregnant women admitted to hospital with confirmed Sars-CoV-2 infection between 01/03/2020 and 14/04/2020. 694 comparison women who gave birth between 01/11/2017 and 31/10/2018. Main outcome measures: Incidence of maternal hospitalisation, infant infection MESHD. Rates of maternal death, level 3 critical care unit admission, preterm birth, stillbirth MESHD, early neonatal death MESHD, perinatal death; odds ratios for infected versus comparison women. Results: Estimated incidence of hospitalisation with confirmed SARS-CoV-2 in pregnancy 4.9 per 1000 maternities (95%CI 4.5-5.4). The median gestation at symptom onset TRANS was 34 weeks (IQR 29-38). Black or other minority ethnicity (aOR 4.49, 95%CI 3.37-6.00), older maternal age TRANS (aOR 1.35, 95%CI 1.01-1.81 comparing women aged TRANS 35+ with those aged TRANS 30-34), overweight HP and obesity HP obesity MESHD (aORs 1.91, 95%CI 1.37-2.68 and 2.20, 95%CI 1.56-3.10 respectively compared to women with a BMI<25kg/m2) and pre-existing comorbidities (aOR 1.52, 95%CI 1.12-2.06) were associated with admission with SARS-CoV-2 during pregnancy. 247 women (58%) gave birth or had a pregnancy loss; 180 (73%) gave birth at term. 40 (9%) hospitalised women required respiratory support. Twelve infants (5%) tested positive for SARS-CoV-2 RNA, six of these infants within the first 12 hours after birth. Conclusions: The majority of pregnant women hospitalised with SARS-CoV-2 were in the late second or third trimester, supporting guidance for continued social distancing measures in later pregnancy. Most had good outcomes and transmission TRANS of SARS-CoV-2 to infants was uncommon. The strong association between admission with infection MESHD and black or minority ethnicity requires urgent investigation and explanation. Study Registration: ISRCTN 40092247

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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