Corpus overview


MeSH Disease

Human Phenotype

Anxiety (5)

Cough (5)

Fever (5)

Fatigue (3)

Myalgia (2)


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    Epidemiology and clinical outcome of COVID-19: A multi-centre cross sectional study from Bangladesh

    Authors: Adnan Mannan; H.M. Hamidullah Mehedi; Naim Hasan Chy; Md. Omar Qayum; Farhana Akter; Abdur Rob; Prasun Biswas; Sanjida Hossain; Mustak Ibn Ayub; Nardin Rezk; Annarita Giliberti; Alessandra Renieri; Yiheng Chen; Sirui Zhou; Vincenzo Forgetta; J Brent Richards

    doi:10.1101/2020.09.09.20191114 Date: 2020-09-10 Source: medRxiv

    Objectives: To investigate SARS-CoV-2 associated epidemiology and clinical outcomes in Bangladesh to understand the course of COVID-19 pandemic and suggest prevention measures. Methods: A cross-sectional retrospective study was conducted among 1,021 RT-PCR confirmed but recovered COVID-19 cases from six participating hospitals in Bangladesh. Results: Of the total sample, 111 (10.9%) cases were asymptomatic TRANS while the number of symptomatic cases were 910 (89.1%). Higher prevalence SERO of COVID-19 persisted in the male TRANS population (75%) and for the 31-40 age group TRANS. More than 85% of the samples reported BCG vaccination mark. Common symptoms observed in our study samples were fever HP fever MESHD (72.4%), cough HP (55.9%), loss of taste MESHD (40.7%) and body ache MESHD (40%); whereas for the biochemical parameters, Neutrophil (46.4%), D-dimer (46.1%), Ferritin (37.9%) and SGPT (36.8%) levels were found elevated. Post-COVID complications including pain HP pain MESHD (31.8%), loss of concentration (24.4%) and anxiety HP anxiety MESHD or depression (23.1%) were found significantly prevalent. Conclusion: Our study has shown that adult TRANS males TRANS aged TRANS between 31-40 in Bangladesh are more vulnerable to being infected with COVID-19. With an indication for the rising trend of the asymptomatic TRANS cases, deployment of interventions to curb further community spread is necessary to avoid the grave outcomes of COVID-19 in Bangladesh.

    Sociodemographic profile, clinical characteristics, anxiety HP anxiety MESHD, and depression MESHD of 74 patients infected with COVID-19: first report from Bangladesh

    Authors: Dr. Mohammad Jahid Hasan; Dr. Md. Abdullah Saeed Khan; Dr. Monjur Rahman; Dr. Md. Shahnoor Islam; Dr Sourav Debnath; Dr. Jannatul Fardous,; Professor Dr. Mohammad Robed Amin

    doi:10.21203/ Date: 2020-05-30 Source: ResearchSquare

    Background: The pandemic of Corona Virus Disease MESHD 2019 (COVID-19) has cost a large number of lives and is causing substantial mental stress among people. We conducted a study to identify the sociodemographic and clinical characteristics and prevalence SERO of anxiety HP anxiety MESHD and depression MESHD among confirmed COVID-19 cases in Bangladesh.Methods: An online cross-sectional survey using a preformed questionnaire adapted in Google form was conducted for data collection. The form was shared along with a brief introduction and rationale via Facebook, Twitter, Facebook Messenger, Viber, and What’s App. Formal ethical clearance was taken from the Biomedical Research Foundation, Bangladesh. Informed consent was ensured before participation.Results: Seventy-four patients with COVID-19 who had an average age TRANS of 42.59±14.43 years with male TRANS predominance (77%) were included. A total of 29.7% were doing health-care related jobs, and 14.9% lost their jobs due to COVID-19. Patients had a median income of BDT 30000. Of all, 87.8% of patients were symptomatic and presented with fever HP fever MESHD (77%), cough HP (58.8%), breathlessness (24.3%), myalgia HP myalgia MESHD (24.3%), sore throat (21.6%), fatigue HP fatigue MESHD (17.6%), nausea and/or vomiting HP nausea and/or vomiting MESHD (12.2%), headache HP headache MESHD (12.2%), runny nose (9.5%), chest pain HP chest pain MESHD (9.5%), diarrhea HP diarrhea MESHD (8.1%), ARDS (2.7%), stuffy nose (2.7%), conjunctivitis HP conjunctivitis MESHD (1.4%) and oral ulcer HP oral ulcer MESHD (1.4%). Overall, the prevalence SERO of anxiety HP anxiety MESHD and depression was 60% and 52.9%, respectively. Among the participants, 11.4% had only anxiety HP anxiety MESHD, 4.3% had only depression MESHD and 48.6% had both.Conclusion: Patients were mostly middle aged TRANS, male TRANS and healthy workers. Typical presentations were fever HP fever MESHD and cough HP cough MESHD. Nearly two-thirds of the patients had either or both anxiety HP anxiety MESHD and depression.

    Early assessment of knowledge, attitudes, anxiety HP anxiety MESHD and behavioral adaptations of Connecticut residents to COVID-19

    Authors: Toan Ha; Stephen Schensul; Judy Lewis; Stacey Brown

    doi:10.1101/2020.05.18.20082073 Date: 2020-05-20 Source: medRxiv

    Objectives. To assess knowledge, attitudes, anxiety HP anxiety MESHD and behavioral adaptations to COVID-19. Methods. A cross-sectional study was conducted among non-healthcare-related participants after a stringent stay-at-home directive was implemented. Multivariate logistic regression analysis was conducted to identify factors associated with anxiety HP anxiety MESHD, perceived seriousness of COVID-19 and loneliness. Results. A total of 464 participants responded to the survey. Most participants recognized cough HP, shortness of breath MESHD and fever HP fever MESHD as primary symptoms of COVID-19. Nearly 50% reported high levels of anxiety HP anxiety MESHD to COVID-19 and 48% reported being loneliness during the social isolation. Those with higher level of COVID-19 knowledge had 1.20 times higher levels with anxiety HP anxiety MESHD. Being married had 1.79 times higher levels of anxiety HP anxiety MESHD about COVID-19. Older age TRANS was associated with loneliness during the social isolation. Older age TRANS was also associated with taking the pandemic seriously. Females TRANS were less likely to report loneliness than males TRANS. Conclusions. It is crucial for the public health authorities not only provide accurate and scientific information about the COVID-19 promoting protective behavior changes but also to minimize anxiety HP anxiety MESHD through supportive messages and recommendations for positive coping strategies and timely offering of counseling services for those in need.

    A one-year hospital-based prospective CVOID-19 open-cohort in the Eastern Mediterranean region: The Khorshid COVID Cohort (KCC) study

    Authors: Ramin Sami; Forogh Soltaninejad; Babak Amra; Zohreh Naderi; Shaghayegh Haghjooy Javanmard; Bijan Iraj; Somayeh Haji Ahmadi; Azin Shayganfar; Mehrnegar Dehghan; Nilufar Khademi; Nastaran Sadat Hosseini; Mojgan Mortazavi; Marjan Mansourian; Miquel Angel Mananas; Hamid Reza Marateb; Peyman Adibi

    doi:10.1101/2020.05.11.20096727 Date: 2020-05-15 Source: medRxiv

    The COVID-19 is rapidly scattering worldwide, and the number of cases in the Eastern Mediterranean Region is rising, there is a need for immediate targeted actions. We designed a longitudinal study in a hot outbreak zone to analyze the serial findings between infected MESHD patients for detecting temporal changes from February 2020. In a hospital-based open-cohort study, patients are followed from admission until one year from their discharge (the 1st, 4th, 12th weeks, and the first year). The measurements included demographic, socio-economics, symptoms, health service diagnosis and treatment, contact history, and psychological variables. The signs improvement, death MESHD, length of stay in hospital were considered as primary, and impaired pulmonary function and psychotic disorders MESHD were considered as main secondary outcomes. Notably, In the last two follow-ups, each patient attends the hospital to complete the Patient Health Questionnaire-9 (PHQ-9) and the Depression Anxiety Stress MESHD Anxiety HP Stress Scales (DASS-21). Moreover, clinical symptoms and respiratory functions are being determined in such follow-ups. Among the first 600 COVID-19 cases, a total of 490 patients with complete information (39% female TRANS; the average age TRANS of 57 {+/-} 15 years) were analyzed. Seven percent of these patients died. The three main leading causes of admission were: fever HP fever MESHD (77%), dry cough MESHD cough HP (73%), and fatigue HP fatigue MESHD (69%). The most prevalent comorbidities between COVID-19 patients were hypertension HP hypertension MESHD (35%), diabetes MESHD (28%), and ischemic heart disease MESHD (14%). The percentage of primary composite endpoints (PCEP), defined as death MESHD, the use of mechanical ventilation, or admission to an intensive care unit was 18%. The following comorbidities were significantly different in the positive and negative PCEP groups: acute kidney disease MESHD (p=0.008) and diabetes MESHD (p=0.026). For signs and symptoms, fatigue HP fatigue MESHD (p=0.020) and sore throat (p=0.001) were significantly different. This long-term prospective Cohort may support healthcare professionals in the management of resources following this pandemic.

    A study on the clinical characteristics and management of patients with mild cases of COVID-19 in shelter hospitals from China

    Authors: Tao FENG; Canhua YANG; Guiying LI; Daoye LIANG; Xinju JIA; Jiping TANG; Xinsen ZOU; Zheng Li

    doi:10.21203/ Date: 2020-04-19 Source: ResearchSquare

    Background: To review the clinical characteristics of patients with mild cases of novel coronavirus disease MESHD (COVID-19) pneumonia HP pneumonia MESHD admitted to shelter hospitals and to investigate the management patterns of shelter hospitals. Methods: We collected and analyzed the case data of 931 patients of their general conditions, main clinical presentations, outcomes, laboratory results, imaging. Results: The average age TRANS of patients with mild cases of COVID-19 was (46.68 ± 12.13) years. There was no significant difference in incidence between males TRANS and females TRANS. The most common clinical presentations were fever HP fever MESHD (60.79%), cough HP (47.37%), myalgia HP myalgia MESHD and fatigue HP fatigue MESHD (17.40%), sore throat (13.86%), sputum (13.86%), diarrhea HP diarrhea MESHD (9.98%), chest distress and dyspnea MESHD dyspnea HP (8.38%), nasal congestion (6.02%), and runny nose (5.69%), while 10.10% were asymptomatic TRANS. In addition, anxiety HP anxiety MESHD and insomnia HP insomnia MESHD were present in 12.13% of cases. COVID-19 clinical type: mild, 248 cases (26.64%); moderate, 683 cases (73.36%). Blood SERO biochemical examination showed that some patients exhibited WBC count (26.32%) lower to normal. Most patients tested positive for novel coronavirus nucleic acid (55.45%), while 44.55% tested negative. The rate of positive chest computed tomography (CT )examination findings was 94.36%. The most common change were ground-glass opacities (48.70%) and multiple patchy opacities (44.58%). Moreover, 65 patients (6.98%) were transferred to designated hospital, primarily due to exacerbation of novel coronavirus pneumonia MESHD pneumonia HP (32 cases, 49.2%). Conclusions: COVID-19 patients in shelter hospitals were in a relatively mild overall condition and were predominantly of the moderate clinical type. Attention should be paid to asymptomatic TRANS positive patients and patients without respiratory symptoms. CT is still the main patient screening method. Shelter hospitals can carry the burden of epidemic prevention and treatment of patients with mild cases of COVID-19.

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MeSH Disease
Human Phenotype

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