Corpus overview


MeSH Disease

Human Phenotype


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    A population-level analysis of changes in diel rhythms and sleep and their association with negative emotions during the outbreak of COVID-19 in China

    Authors: Siyu Chen; Tianyu Huang; Yutao Huang; Cenxing Nie; Jingwen Liang; Xinyan Liu; Yanwen Xu; Jinhu Guo

    doi:10.21203/ Date: 2020-09-11 Source: ResearchSquare

    Introduction: From December 2019, COVID-19 (novel coronavirus pneumonia MESHD pneumonia HP) began spreading in China and has significantly affected the industrial economy and peoples’ daily lifestyle. Beginning on January 23, the public was asked to constantly stay at home for quarantine and community containment.Methods: To assess the effects of the changes in diel rhythms and sleep and their association with negative emotions during the COVID-19 outbreak, a questionnaire was administered to 451 responders for analysis between January 20, 2020, and January 31, 2020, in China.Results: We found that 34.6% of the participants reported diel rhythm disturbance. Moreover, 67.2% of the participants presented negative emotions regarding the pandemic situation, including worry, fear, downheartedness, anxiety HP anxiety MESHD, depression MESHD, and stupefaction; among them, worry was the most prevalent. Gender TRANS and age TRANS were significant factors for changes in the diel phases and emotions. There was a correlation between diel rhythm alterations and negative emotions. Three factors, i.e., the Spring Festival holiday, quarantines and concern regarding the pandemic situation, were associated with changes in diel rhythms, sleep, and negative emotions during the pandemic period. Holiday jet lag, quarantine (or community containment), and concerns regarding the pandemic situation had significant effects on diel rhythms, sleep and negative emotion in a substantial part of the population. Conclusions: Our findings suggest that diel rhythms and sleep and their association with negative emotions in COVID-19 patients and the normal population need to be considered. Moreover, the adjustment of diel rhythms could help relieve negative effects and improve the global health during the pandemic period.

    Socio-emotional Strengths Against Psychopathology and Suicidal Ideation HP in Fear of Covid-19

    Authors: Victoria Soto-Sanz; Raquel Falcó; José Antonio Piqueras

    doi:10.21203/ Date: 2020-09-07 Source: ResearchSquare

    Coronavirus disease MESHD (COVID-19) has caused a global health crisis. It also leads to different types of psychosocial problems in society as a result of preventive health measures and the disease itself. Among others, psychopathological symptoms MESHD and suicide behaviors have increased. The PsicorecurSOS COVID-19 online protocol was designed. At baseline, 1,020 Spanish adults TRANS were assessed, during confinement, for sociodemographics, fear of COVID-19, anxious-depressive symptoms MESHD, covitality, and suicidal ideation HP. Reliability, descriptive, and frequency analyses were carried out, and the computer tool SPSS PROCESS was used to carry out a conditional process analysis (model 59). A total of 595 participants were included (58.30% response rate from baseline; mean age TRANS = 37.18 [SD = 13.30]; 72.44% female TRANS). Regarding suicidal ideation HP, 12% responded differently to “never,” 19.3% exceeded the cutoff point on the anxiety HP anxiety MESHD scale, and 24% on the depression MESHD scale. Moderate mediation analysis explained 27% of the variance in suicidal ideation HP. In addition, the indirect effect of moderate mediation was significant (b = -.003, SE = .002 with the presence of covitality; and b = .01, SE = .003 absence of covitality). Sex and age TRANS did not influence the overall outcome of the model. The data from this study can serve as a starting point for generating social and health treatment initiatives based on self-examination of anxiety HP anxiety MESHD-depressive symptoms and increasing socio-emotional skills in order to prevent and alleviate the psychosocial effects of the pandemic.

    COVID-19 pandemic and self-reported symptoms of depression MESHD, anxiety HP anxiety MESHD, and stress among health care workers in Ethiopia MESHD

    Authors: kemal Jemal; Berhanu Senbeta; Tinsae Abeya Geleta; Mukemil Awol

    doi:10.21203/ Date: 2020-08-19 Source: ResearchSquare

    BackgroundThe Coronavirus Diseases 2019 (COVID-19) pandemic has become a major problem in many of the world nations including Ethiopia. Moreover, it is a public health emergency of the community concern and poses a mental health problem to health care workers (HCWs). Therefore, this study aimed to assess the level of self-reporting symptoms of depression MESHD, anxiety HP anxiety MESHD, and stress during the COVID-19 pandemic among healthcare workers in Ethiopia.MethodsAn institutional-based cross-sectional study was conducted using an online survey from June 25, 2020, to July 25, 2020, in Ethiopia. The data were collected using a self-reported Depression MESHD, Anxiety HP Anxiety MESHD, and Stress Scale (DASS-21). Data were cleaned, coded, and entered using Epi info version 7.5.1 and exported for analyzed to the Social Science package software Version 23 Statistical Package. Moreover, multiple logistic regression analysis was used to identify the associated factors at p-value less than 0.05.ResultsA total of 816 HCWs responded to self-reporting questions. From HCWs who screened positive for depression MESHD, anxiety HP anxiety MESHD, and stress; 60.3%, 78%, and 33.8% of them had scored moderate to extremely severe symptoms of depression MESHD, anxiety HP anxiety MESHD, and stress respectively. Females TRANS, HCWs who working in Oromiya Specialized Zone, medical laboratory professionals, and HCWs who have working in the COVID-19 treatment isolation department were significantly associated with depression MESHD, anxiety HP anxiety MESHD, and stress.ConcussionIn this study, health care workers had reported a high prevalence SERO of depression MESHD, anxiety HP anxiety MESHD, and stress symptoms. Female TRANS gender TRANS, Oromiya especial zone, medical laboratory professionals, and HCWs who have working in the COVID-19 treatment isolation centers were significantly associated with depression MESHD, anxiety HP anxiety MESHD, and stress. Psychological intervention for health care workers in central Ethiopia needs special attention.

    Risk Factors for Adolescents' Mental Health During the COVID-19 Pandemic: A Comparison between Wuhan and Other Areas in China

    Authors: Shitao Chen; Zeyuan Cheng; Jing Wu

    doi:10.21203/ Date: 2020-08-13 Source: ResearchSquare

    Background: The outbreak of Coronavirus Disease MESHD is causing considerable acute risk to public health and might have an unanticipated impact on the mental health of children TRANS and adolescents in the long run. This study aims to understand whether there is a clinically significant difference in anxiety HP anxiety MESHD, depression MESHD, and parental rearing style when comparing adolescents from Wuhan and other cities in China. This study also intends to examine whether gender TRANS, grade in school, single child TRANS status, online learning participation MESHD, parents TRANS' involvement in COVID-19 related work, and parents TRANS being quarantined or infected due to the disease would lead to clinically significant differences in anxiety HP anxiety MESHD and depression. Beyond that, this study explored the pathways among the different variables in order to better understand how these factors play a part in impacting adolescents' mental health condition. Results: Results showed that there was a statistically significant difference in anxiety HP anxiety MESHD symptoms between participants who were from Wuhan compared to other areas, but not in depressive symptoms MESHD. In addition, participants’ grade level, gender TRANS, relative being infected, and study online have direct positive predictive value SERO for depressive MESHD and anxiety HP anxiety MESHD symptoms, whereas location and sibling status have indirect predictive value. Having relatives who participated in COVID-19 related work had positive direct predictive value only toward depression MESHD, but not anxiety HP anxiety MESHD.Conclusions: This study discovered several risk factors for adolescents’ depression MESHD and anxiety HP anxiety MESHD during the pandemic. It also called for a greater awareness of Wuhan parents’ mental wellbeing and recommended a systematic approach for mental health prevention and intervention. 

    Mental Health Impacts for International Students During the COVID-19 Pandemic in China

    Authors: Xiaoping Wang; Khamlesh Hujjaree; Fanglan Wang

    doi:10.21203/ Date: 2020-07-26 Source: ResearchSquare

    The outbreak of Coronavirus disease MESHD 2019 (COVID-19), has led to the quarantine of many residents in their homes worldwide. Some of these people might develop mental health problems, and many solutions have been put in place to address the mental health issues of patients and health professionals affected by the disease. However, not much attention has been given to international students studying in China. The present study aims to conduct an online survey to investigate the mental health status of international students from Changsha city, China.Materials and Methods: A WeChat-based survey program comprised of questions on demographic information gender TRANS, grade year, duration and status of quarantine, duration of sleep, worries about graduation, being able to go to school and presence or absence of a sense of security; as well as questions from the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety HP Anxiety MESHD Disorder-7 (GAD-7) scale and State-Trait Anxiety HP Anxiety MESHD Inventory(STAI).Results: The prevalence SERO of depression MESHD was 59.4% and the prevalence SERO of anxiety HP anxiety MESHD was 37.8%. The STAI-Y1 STATE scores had a mean value (mean) of 41.42, standard deviation (S.D) of 10.89 and STAI-Y2 TRAIT scores had a mean value (mean) of 41.85, standard deviation (S.D) of 11.13.  The risk factors of anxiety HP anxiety MESHD or depression MESHD were Sleep duration, worrying about graduation in varying degrees, School time, and feeling secure in varying degrees. Higher the Patient Health Questionnaire-9 score and higher Generalized Anxiety HP Anxiety MESHD Disorder-7 score and higher STAI-Y1 STATE scores were associated with higher STAI-Y2 TRAIT scores.Conclusion: The present study implies that the university needs to consider planning for acute and long-term psychological help services for international students.

    An overview of current mental health in the general population of Australia during the COVID-19 pandemic: Results from the COLLATE project

    Authors: Susan Rossell; Erica Neill; Andrea Phillipou; Eric Tan; Wei Lin Toh; Tamsyn Van Rheenen; Denny Meyer

    doi:10.1101/2020.07.16.20155887 Date: 2020-07-18 Source: medRxiv

    The novel coronavirus disease MESHD (COVID-19) poses significant mental health challenges globally; however, to date, there is limited community level data. This study reports on the first wave of data from the COLLATE project (COvid-19 and you: mentaL heaLth in AusTralia now survEy), an ongoing study aimed at understanding the impact of the COVID-19 pandemic on the mental health and well-being of Australians. This paper addresses prevailing primary concerns related to the COVID-19 pandemic, current levels of negative emotions and risk factors predicting these negative emotions. On April 1st to 4th 2020, 5158 adult TRANS members of the Australian general public completed an online survey. Participants ranked their top ten current primary concerns about COVID-19, and completed standardized measures to ascertain levels of negative emotions (specifically, depression MESHD, anxiety HP anxiety MESHD and stress). Socio-demographic information was also collected and used in the assessment of risk factors. The top three primary concerns were all related to the health and well-being of family and loved ones. As expected, levels of negative emotion were exceptionally high. Modelling of predictors of negative emotions established several risk factors related to demographic variables, personal vulnerabilities, financial stresses, and social distancing experiences; particularly being young, being female TRANS, or having a mental illness diagnosis. The data provides important characterization of the current mental health of Australians during the COVID-19 pandemic. Critically MESHD, it appears that specific groups in the Australian community may need special attention to ensure their mental health is protected during these difficult times. The data further suggests the need for immediate action to combat high levels of psychological distress, along with the exacerbation of mental health conditions, in relation to the COVID-19 pandemic in Australia. These results may provide some direction for international researchers hoping to characterize similar issues in other countries.

    COVID-19 misinformation: mere harmless delusions HP or much more? A knowledge and attitude cross-sectional study among the general public residing in Jordan

    Authors: Malik Sallam; Deema Dababseh; Alaa Yaseen; Ayat Al-Haidar; Duaa Taim; Huda Eid; Nidaa A. Ababneh; Faris G. Bakri; Azmi Mahafzah

    doi:10.1101/2020.07.13.20152694 Date: 2020-07-15 Source: medRxiv

    Abstract Since the emergence of the recent coronavirus disease MESHD 2019 (COVID-19) and its spread as a pandemic, media was teeming with misinformation that led to psychologic, social and economic consequences among the global public. Probing knowledge and anxiety HP anxiety MESHD regarding this novel infectious disease MESHD is necessary to identify gaps and sources of misinformation which can help public health efforts to design and implement more focused interventional measures. The aim of this study was to evaluate the knowledge, attitude and effects of misinformation about COVID-19 on anxiety HP anxiety MESHD level among the general public residing in Jordan. An online survey was used that targeted people aged TRANS 18 and above and residing in Jordan. The questionnaire included items on the following: demographic characteristics of the participants, knowledge about COVID-19, anxiety HP anxiety MESHD level and misconceptions regarding the origin of the pandemic. The total number of participants included in final analysis was 3150. The study population was predominantly females TRANS (76.0%), with mean age TRANS of 31 years. The overall knowledge of COVID-19 was satisfactory. Older age TRANS, male TRANS gender TRANS, lower monthly income and educational levels, smoking and history of chronic disease MESHD were associated with perceiving COVID-19 as a very dangerous disease. Variables that were associated with a higher anxiety HP anxiety MESHD level during the pandemic included: lower monthly income and educational level, residence outside the capital (Amman) and history of smoking. Misinformation about the origin of the pandemic (being part of a conspiracy, biologic warfare and the 5G networks role) was also associated with higher anxiety HP anxiety MESHD and lower knowledge about the disease. Social media platforms, TV and news releases were the most common sources of information about the pandemic. The study showed the potential harmful effects of misinformation on the general public and emphasized the need to meticulously deliver timely and accurate information about the pandemic to lessen the health, social and psychological impact of the disease MESHD.

    Psychosocial impact of respiratory infectious disease pandemics on children TRANS: a systematic review

    Authors: Chenran Wang; Shuyue Xiao; Yijie Sun; Jinpeng Wang; Tao Xu

    doi:10.21203/ Date: 2020-07-13 Source: ResearchSquare

    Objective To examine the impact of respiratory infectious disease MESHD pandemics in the new millennium on mental health, behavioral responses, and parenting TRANS practices in children TRANS, and provide further intervention directions to mitigate negative effects of the 2019 novel coronavirus disease MESHD (COVID-19).Methods We conducted a systemic literature review of researches from January 2003 to May 2020 with three mainstream electronic databases including PubMed, Web of Science, and China National Knowledge Infrastructure. Quality of included studies were assessed using Agency for Healthcare Research and Quality (AHRQ), Newcastle-Ottawa Scale (NOS), and Critical Appraisal Skills Programme (CASP) according to different study design. Further directions were identified for developing appropriate interventions.Results Twenty-four studies conducted in the context of severe acute respiratory syndrome MESHD (SARS) (n = 10), influenza A (H1N1) (n = 3), and COVID-19 (n = 11) pandemics met the inclusion criteria. Children TRANS showed emotional conditions such as anxiety HP anxiety MESHD, fear, and depression MESHD, while psychological responses varied across age TRANS and gender TRANS groups. Children TRANS with mental illness MESHD history experienced an exacerbation of psychological symptoms. The pandemics changed hygiene habits and learning styles, and led to the increased participation in unfavorable lifestyles. For families with pediatric patients, the pandemic decreased parents’ participation in providing family-centered care and threatened to supportive family relationship and effective parents TRANS- child TRANS communication.Conclusion The emerging virus outbreaks and subsequent disease-control measures have impacts on mental health status, behavioral responses, and parenting TRANS practices in children TRANS. In response to COVID-19, greater efforts taking into account children’s developmental stage should be made to implement evidence-based psychological interventions, enhance effective communication, and encourage collaboration.

    Psychological Distress during COVID-19 Curfews and Social Distancing in Saudi Arabia: A Cross-Sectional Study

    Authors: Badrah S Alghamdi; Yasser AlAtawi; Fahad S. AlShehri; Haythum O. Tayeb; Hanin Abo Abo Taleb; Amal Binsalman

    doi:10.21203/ Date: 2020-07-06 Source: ResearchSquare

    Background Coronavirus disease MESHD 2019 (COVID-19) has spread to over 150 countries worldwide. Since the first case of COVID-19 was confirmed in Saudi Arabia, cases have continued to escalate exponentially. The COVID-19 outbreak has had a negative effect on mental health and well-being. The study aim was to investigate the effects of the strict national regulations associated with the COVID-19 pandemic on the population’s mental health.Methods This was a cross-sectional study of a convenience sample of Saudi residents. Participants completed an online questionnaire after 1 month of a nationwide 24-hour curfew. We measured psychological distress using the Depression MESHD, Anxiety HP Anxiety MESHD and Stress Scale-21 (DASS-21). We ran binary logistic regression analyses to detect variables that significantly predicted DASS-21 scores.Results The sample comprised 2252 Saudi residents. The DASS-21 score means and standard deviations for depression MESHD and anxiety HP anxiety MESHD for the whole sample (10.73 ± 10.29 and 6.98 ± 8.30, respectively) were in the range of mild depression MESHD and anxiety HP anxiety MESHD. In contrast, the mean DASS-21 stress score was within the normal range (11.97 ± 10.80). The mean stress score for healthcare workers was within normal range (13.70 ± 10.68), but was significantly higher than the mean score for the public (11.56 ± 10.89; P = .0006). Several variables (e.g. age TRANS, gender TRANS and history of contact with confirmed COVID-19 cases) were significantly associated with higher DASS-21 scores.Conclusions The COVID-19 pandemic has created a psychological burden. Therefore, there is an urgent need to implement emergency psychological interventions to reduce the negative psychosocial effects of the pandemic on public mental health.

    The effect of the COVID-19 induced lockdown on nutrition, health and lifestyle patterns among adults TRANS in Zimbabwe

    Authors: Tonderayi M Matsungo; Prosper Chopera

    doi:10.1101/2020.06.16.20130278 Date: 2020-06-19 Source: medRxiv

    Background: The 2019 coronavirus disease MESHD (COVID-19) is a global public health nightmare resulting in lockdowns, associated diet and lifestyle changes and constraint public health delivery. Objective: To investigate the impacts of the COVID-19 induced lockdown in Zimbabwe on nutrition, physical activity and lifestyle patterns among Zimbabwean population aged TRANS [≥]18years. Methods: A cross-sectional online survey was conducted using a structured questionnaire to collect information on demographics ( age TRANS, gender TRANS, place of residence, current employment), food system dimensions, diet and physical activity patterns, stress and anxiety HP anxiety MESHD, body image perceptions, lifestyle behaviours like smoking, alcohol intake, screen time, and ease of access to health services. Electronic informed consent was obtained from all participants prior to completing the survey. Results: The majority of the participants were between the ages TRANS of 31-40 years, were female TRANS (63.0%) and had tertiary education (91.3%). The lockdown resulted in increase in food prices (94.8%) and decrease in availability of nutritious foods (64%). Most (62.5%) of the participants reported a reduction in their physical activity levels. The prevalence SERO of Generalised Anxiety HP Anxiety MESHD Disorder (GAD) was 40.4% and mostly affecting females TRANS [63.5%, P=0.909), 31-40 years age group TRANS (49.6%, P=0.886). Based on the BMI-based Silhouette Matching Test (BMI-SMT) 44.5% gained weight, 24.3% lost weight and 31.2% did not have weight change. The paired samples T test showed that there was a significant increase in perceived body weight (P<0.001). More than half (59.6%) reported having difficulties accessing drugs and medication and 37.8% growth monitoring services. Conclusions: The lockdown period was associated with increase in food prizes, decrease in dietary diversification, elevated stress, disrupted diet and consumption patterns. There was low levels of physical activity and perceived weight gained during the lockdown period. However, there are still lots on unknowns concerning the COVID-19 pandemic future studies with larger population are required.

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MeSH Disease
Human Phenotype

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