Corpus overview


MeSH Disease

Human Phenotype

Anxiety (94)

Pain (6)

Fever (6)

Cough (5)

Insomnia (5)


    displaying 1 - 10 records in total 94
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    COPD in the time of COVID-19: An analysis of acute exacerbations and reported behavioural changes in patients with COPD MESHD

    Authors: Hamish Joseph Cameron McAULEY; Kate Hadley; Omer Elneima; Christopher E Brightline; Rachael Evans; Michael C Steiner; Neil Greening; Javed Akram; Ravi K Amaravadi; Derek C Angus; Yaseen M Arabi; Shehnoor Azhar; Lindsey R Baden; Arthur W Baker; Leila Belkhir; Thomas Benfield; Marvin A H Berrevoets; Cheng-Pin Chen; Tsung-Chia Chen; Shu-Hsing Cheng; Chien-Yu Cheng; Wei-Sheng Chung; Yehuda Z Cohen; Lisa N Cowan; Olav Dalgard; Fernando F de Almeida e Val; Marcus V G de Lacerda; Gisely C de Melo; Lennie Derde; Vincent Dubee; Anissa Elfakir; Anthony C Gordon; Carmen M Hernandez-Cardenas; Thomas Hills; Andy I M Hoepelman; Yi-Wen Huang; Bruno Igau; Ronghua Jin; Felipe Jurado-Camacho; Khalid S Khan; Peter G Kremsner; Benno Kreuels; Cheng-Yu Kuo; Thuy Le; Yi-Chun Lin; Wu-Pu Lin; Tse-Hung Lin; Magnus Nakrem Lyngbakken; Colin McArthur; Bryan McVerry; Patricia Meza-Meneses; Wuelton M Monteiro; Susan C Morpeth; Ahmad Mourad; Mark J Mulligan; Srinivas Murthy; Susanna Naggie; Shanti Narayanasamy; Alistair Nichol; Lewis A Novack; Sean M O'Brien; Nwora Lance Okeke; Lena Perez; Rogelio Perez-Padilla; Laurent Perrin; Arantxa Remigio-Luna; Norma E Rivera-Martinez; Frank W Rockhold; Sebastian Rodriguez-Llamazares; Robert Rolfe; Rossana Rosa; Helge Rosjo; Vanderson S Sampaio; Todd B Seto; Muhammad Shehzad; Shaimaa Soliman; Jason E Stout; Ireri Thirion-Romero; Andrea B Troxel; Ting-Yu Tseng; Nicholas A Turner; Robert J Ulrich; Stephen R Walsh; Steve A Webb; Jesper M Weehuizen; Maria Velinova; Hon-Lai Wong; Rebekah Wrenn; Fernando G Zampieri; Wu Zhong; David Moher; Steven N Goodman; John P A Ioannidis; Lars G Hemkens

    doi:10.1101/2020.09.18.20197202 Date: 2020-09-18 Source: medRxiv

    ABSTRACT Introduction: The impact of the SARS-CoV-2 pandemic, and lockdown measures, on acute exacerbations of COPD MESHD (AECOPD) is unknown. We aimed to evaluate the change in AECOPD treatment frequency during the first six weeks of lockdown in the UK compared with 2019 and assess changes in self-reported behaviour and well-being. Methods: In this observational study patients with established COPD were recruited. Exacerbation frequency was measured in the first six weeks of COVID lockdown and compared with the same period in 2019 using electronic health records. A telephone survey was used to assess changes in anxiety HP anxiety MESHD, inhaler adherence, physical activity, shopping and visitor behaviour during the pre-lockdown and lockdown periods compared to normal. Results: 160 participants were recruited (mean [SD] age TRANS 67.3 [8.1] years, 88 [55%] male TRANS, FEV1 34.3 [13] % predicted) and 140 [88%] reported at least one AECOPD in the previous year. Significantly more community treated exacerbations were observed in 2020 compared with 2019 (126 vs 99, p=0.026). The increase was as a result of multiple courses of treatment, with a similar proportion of patients receiving at least one course (34.4% vs 33.8%). During 'lockdown' participants reported significantly increased anxiety HP anxiety MESHD, adherence to their preventative inhalers, and good adherence to shielding advice (all p<0.001). A significant reduction in self-reported physical activity and visitors was reported (both p<0.001). Discussion: Treatment for AECOPD MESHD events increased during the first six weeks of the SARS-CoV-2 pandemic in the UK compared to 2019. This was associated with increased symptoms of anxiety HP anxiety MESHD and significant behavioural change.

    Perceived risk, anxiety HP anxiety MESHD and protective health behaviours during the early phase of coronavirus (COVID-19) pandemic in Nigeria

    Authors: Tosin Philip Oyetunji; Timolthy Tomiwa Oyelakin,; Olusegun Ayomikun Ogunmola; Olorunyomi Felix Olorunsogbon; Foluso O. Ajayi

    doi:10.21203/ Date: 2020-09-14 Source: ResearchSquare

    Background: Pandemics such as the current COVID-19 pandemic are often associated with heightened fears and significant adjustments in health behaviours. Aim: This study was aimed to assess perceived risk, anxiety HP anxiety MESHD and protective health behaviours of the general public during the early phase of the coronavirus (COVID-19) pandemic in NigeriaMethods: A cross-sectional study among 1197 respondents aged TRANS 18 years and above between April 27th to May 16th, 2020. Result: More than half (61.9%) of the respondents have high risk perception towards COVID-19. Using the seven-item Generalized Anxiety HP Anxiety MESHD Disorder (GAD-7) scale, high anxiety HP anxiety MESHD level was found in 37.2% of the study respondents. Male TRANS gender TRANS (OR=1.38,CI=1.09-1.74), being employed (OR=1.53,CI = 1.21- 1.95) and high risk perception (OR=1.33, CI = 1.05-1.69) were positively associated with observance of more than one protective measure against COVID-19. Having not more than 12 years of education (OR=0.51, CI=0.32-0.81) was negatively associated with observance of more than one protective behaviour. High risk perception (OR=1.82; CI=1.42-2.34), having not more than 12 years of education (OR=1.73; CI= 1.13-2.64), and being employed (OR =1.29; CI=1.01-1.64) were positively associated with anxiety HP anxiety MESHD. Being aged TRANS 25-34 years (OR=0.34; CI =0.12-0.94) and being aged TRANS 35-54 years (OR=0.30; CI=0.10-0.85) were found to be protective against developing COVID-19- related anxiety HP anxiety MESHD.Conclusions: This study showed that risk perception has influence on both anxiety HP anxiety MESHD and observance of protective behaviours. Being a novel experience, this research has implications to support current and future response to a pandemic experience.

    Factors associated with the mental health of adolescent university students during COVID-19 quarantine in Japan

    Authors: Yuko Hirano; Koichi Aramaki; Sayuka Ota

    doi:10.21203/ Date: 2020-09-11 Source: ResearchSquare

    Background: University students in Japan have been quarantined during the current COVID-19 pandemic. The resulting social avoidance may increase students’ anxiety HP anxiety MESHD about the pandemic and adversely affect their mental health. To obtain basic data for a university health policy, we investigated factors associated with the mental health status of 570 students of a national university in Japan during quarantine. Methods: Participants completed an online questionnaire assessing respondent characteristics ( gender TRANS, age TRANS, department, domicile status), subjective sense of anxiety HP anxiety MESHD about COVID-19, and number of social supports. The General Health Questionnaire (GHQ)-12 was used as a marker for mental health status, and sense of coherence (SOC) was used as a marker for stress resistance. Chi-square tests, t-tests, Pearson’s correlation coefficients, and multiple regression analysis were conducted to identify factors associated with GHQ score. Two-way analysis of variance (ANOVA) was conducted to identify the interaction between anxiety HP anxiety MESHD score and SOC scores. Results: Females TRANS showed significantly more adverse mental health than males TRANS. Regardless of gender TRANS, the strongest factor associated with GHQ score was anxiety HP anxiety MESHD about COVID-19, which impaired mental health status, followed by SOC score, which improved mental health status. The ANOVA results showed a significant interaction effect on GHQ scores between anxiety HP anxiety MESHD and SOC score in males TRANS. High SOC scores mitigated the negative effect of anxiety HP anxiety MESHD on mental health more than did low SOC scores, especially in males TRANS with low to medium levels of anxiety HP anxiety MESHD.Conclusions: The results indicate that fear of COVID-19 impaired mental health status, but SOC worked as a buffer to mitigate the negative effect of anxiety HP anxiety MESHD on mental health, especially among male TRANS students. Given the health risks associated with gender TRANS, universities should provide psychological care to encourage students to maintain a confident daily routine and to foster higher SOC, especially for male TRANS students. 

    Lessons from the COVID-19 pandemic: People's experiences and satisfaction with telehealth during the COVID-19 pandemic in Australia

    Authors: Jennifer MJ Isautier; Tessa Copp; Julie Ayre; Erin Cvejic; Gideon Meyerowitz-Katz; Carys Batcup; Carissa Bonner; Rachael Dodd; Brooke Nickel; Kristen Pickles; Samuel Cornell; Thomas Dakin; Kirsten J McCaffery; Aboubacar Sidiki Magassouba; Arsen Arakelyan; Denise Haslwanter; Rohit Jangra; Alev Celikgil; Duncan Kimmel; James H Lee; Margarette Mariano; Antonio Nakouzi; Jose Quiroz; Johanna Rivera; Wendy A Szymczak; Karen Tong; Jason Barnhill; Mattias NE Forsell; Clas Ahlm; Daniel T. Stein; Liise-anne Pirofski; Doctor Y Goldstein; Scott J. Garforth; Steven C. Almo; Johanna P. Daily; Michael B. Prystowsky; James D. Faix; Amy S. Fox; Louis M. Weiss; Jonathan R. Lai; Kartik Chandran

    doi:10.1101/2020.09.10.20192336 Date: 2020-09-11 Source: medRxiv

    Objectives: To determine how participants perceived telehealth consults in comparison to traditional in-person visits, and to investigate whether people believe that telehealth services would be useful beyond the pandemic. Design: A national cross-sectional community survey. Participants: Australian adults TRANS aged TRANS 18 years and over (n=1369). Main outcome measures: Telehealth experiences. Results: Of the 596 telehealth users, the majority of respondents (62%) rated their telehealth experience as "just as good" or "better" than a traditional in-person medical appointment. On average, respondents perceived that telehealth would be moderately to very useful for medical appointments after the COVID-19 pandemic is over (M=3.67 out of 5, SD=1.1). Being male TRANS (p=0.007), having a history of both depression and anxiety MESHD anxiety HP (p=0.037), or lower patient activation (individuals' willingness to take on the role of managing their health/healthcare) (p=0.037) were associated with a poorer telehealth experience. Six overarching themes were identified from free-text responses of why telehealth experience was poorer than a traditional in-person medical appointment: communication is not as effective; limitations with technology; issues with obtaining prescriptions and pathology; reduced confidence in doctor; additional burden for complex care; and inability to be physically examined. Conclusions: Telehealth appointments were reported to be comparable to traditional in-person medical appointments by most of our sample. Telehealth should continue to be offered as a mode of healthcare delivery while the pandemic continues and may be worthwhile beyond the pandemic.

    A population-level analysis of changes in diel rhythms and sleep and their association with negative emotions during the outbreak of COVID-19 in China

    Authors: Siyu Chen; Tianyu Huang; Yutao Huang; Cenxing Nie; Jingwen Liang; Xinyan Liu; Yanwen Xu; Jinhu Guo

    doi:10.21203/ Date: 2020-09-11 Source: ResearchSquare

    Introduction: From December 2019, COVID-19 (novel coronavirus pneumonia MESHD pneumonia HP) began spreading in China and has significantly affected the industrial economy and peoples’ daily lifestyle. Beginning on January 23, the public was asked to constantly stay at home for quarantine and community containment.Methods: To assess the effects of the changes in diel rhythms and sleep and their association with negative emotions during the COVID-19 outbreak, a questionnaire was administered to 451 responders for analysis between January 20, 2020, and January 31, 2020, in China.Results: We found that 34.6% of the participants reported diel rhythm disturbance. Moreover, 67.2% of the participants presented negative emotions regarding the pandemic situation, including worry, fear, downheartedness, anxiety HP anxiety MESHD, depression MESHD, and stupefaction; among them, worry was the most prevalent. Gender TRANS and age TRANS were significant factors for changes in the diel phases and emotions. There was a correlation between diel rhythm alterations and negative emotions. Three factors, i.e., the Spring Festival holiday, quarantines and concern regarding the pandemic situation, were associated with changes in diel rhythms, sleep, and negative emotions during the pandemic period. Holiday jet lag, quarantine (or community containment), and concerns regarding the pandemic situation had significant effects on diel rhythms, sleep and negative emotion in a substantial part of the population. Conclusions: Our findings suggest that diel rhythms and sleep and their association with negative emotions in COVID-19 patients and the normal population need to be considered. Moreover, the adjustment of diel rhythms could help relieve negative effects and improve the global health during the pandemic period.

    Sleep Disturbances HP Disturbances, Anxiety MESHD Anxiety HP, and Burnout during the COVID-19 Pandemic: a nationwide cross-sectional study in Brazilian Healthcare Professionals.

    Authors: Luciano Drager; Daniela Pachito; Claudia Moreno; Almir Tavares Jr.; Silvia G. Conway; Marcia Assis; Danilo A. Sguillar; Gustavo A. Moreira; Andrea Bacelar; Pedro R. Genta; Samantha K Davis; Helen E Kent; Francesca L Mordant; Timothy E Schlub; David L Gordon; David S Khoury; Kanta Subbarao; Deborah Cromer; Tom P Gordon; Amy W Chung; Miles P Davenport; Stephen J Kent

    doi:10.1101/2020.09.08.20190603 Date: 2020-09-10 Source: medRxiv

    Study objectives: To evaluate the impact of COVID-19 pandemic on sleep, anxiety HP anxiety MESHD, and Burnout in healthcare professionals. Methods: A survey was distributed using social media and organizational emails to Brazilian active healthcare professionals during the COVID-19 outbreak. We explored potential associated factors including age TRANS, gender TRANS, occupation, workplace, work hours, income, previous infection MESHD with COVID-19, recent/current contact with COVID-19 patients, regional number of incident deaths due to COVID-19, anxiety HP anxiety MESHD, and burnout. We evaluated new-onset or previous insomnia HP insomnia MESHD worsening (primary outcome), sleep quality, and duration (secondary outcomes). Results: A total of 4,384 health professionals from all regions of the country were included in the analysis (mean age TRANS: 44{+/-}12 years, 76% females TRANS, 53.8% physicians). Overall, 55.7% were assisting patients with COVID-19, and 9.2% had a previous COVID-19 infection MESHD. New-onset insomnia HP insomnia MESHD symptoms or previous insomnia HP insomnia MESHD worsening occurred in 41.4% of respondents in parallel to 13% (n=572) new pharmacological treatments for insomnia HP insomnia MESHD. Prevalent anxiety HP anxiety MESHD and burnout during the pandemic were observed in 44.2% and 21% of participants, respectively. Multivariate analyses showed that females TRANS (OR:1.756; 95% CI 1.487-2.075), weight change (decrease: OR:1.852; 95% CI 1.531-2.240; increase: OR:1.542; 95% CI 1.323-1.799), prevalent anxiety HP anxiety MESHD (OR:3.209; 95% CI 2.796-3.684), new-onset burnout (OR:1.986; 95% CI 1.677-2.352), family income reduction >30% (OR:1.366; 95% CI 1.140-1.636) and assisting patients with COVID-19 (OR:1.293; 95% CI 1.104-1.514) were independently associated with new-onset or worsening of previous insomnia HP insomnia MESHD. Conclusions: We observed a huge burden of insomnia HP insomnia MESHD in healthcare professionals during the COVID-19 pandemic. In this scenario, dedicated approaches for sleep health are highly desirable.

    Epidemiology and clinical outcome of COVID-19: A multi-centre cross sectional study from Bangladesh

    Authors: Adnan Mannan; H.M. Hamidullah Mehedi; Naim Hasan Chy; Md. Omar Qayum; Farhana Akter; Abdur Rob; Prasun Biswas; Sanjida Hossain; Mustak Ibn Ayub; Nardin Rezk; Annarita Giliberti; Alessandra Renieri; Yiheng Chen; Sirui Zhou; Vincenzo Forgetta; J Brent Richards

    doi:10.1101/2020.09.09.20191114 Date: 2020-09-10 Source: medRxiv

    Objectives: To investigate SARS-CoV-2 associated epidemiology and clinical outcomes in Bangladesh to understand the course of COVID-19 pandemic and suggest prevention measures. Methods: A cross-sectional retrospective study was conducted among 1,021 RT-PCR confirmed but recovered COVID-19 cases from six participating hospitals in Bangladesh. Results: Of the total sample, 111 (10.9%) cases were asymptomatic TRANS while the number of symptomatic cases were 910 (89.1%). Higher prevalence SERO of COVID-19 persisted in the male TRANS population (75%) and for the 31-40 age group TRANS. More than 85% of the samples reported BCG vaccination mark. Common symptoms observed in our study samples were fever HP fever MESHD (72.4%), cough HP (55.9%), loss of taste MESHD (40.7%) and body ache MESHD (40%); whereas for the biochemical parameters, Neutrophil (46.4%), D-dimer (46.1%), Ferritin (37.9%) and SGPT (36.8%) levels were found elevated. Post-COVID complications including pain HP pain MESHD (31.8%), loss of concentration (24.4%) and anxiety HP anxiety MESHD or depression (23.1%) were found significantly prevalent. Conclusion: Our study has shown that adult TRANS males TRANS aged TRANS between 31-40 in Bangladesh are more vulnerable to being infected with COVID-19. With an indication for the rising trend of the asymptomatic TRANS cases, deployment of interventions to curb further community spread is necessary to avoid the grave outcomes of COVID-19 in Bangladesh.

    Socio-emotional Strengths Against Psychopathology and Suicidal Ideation HP in Fear of Covid-19

    Authors: Victoria Soto-Sanz; Raquel Falcó; José Antonio Piqueras

    doi:10.21203/ Date: 2020-09-07 Source: ResearchSquare

    Coronavirus disease MESHD (COVID-19) has caused a global health crisis. It also leads to different types of psychosocial problems in society as a result of preventive health measures and the disease itself. Among others, psychopathological symptoms MESHD and suicide behaviors have increased. The PsicorecurSOS COVID-19 online protocol was designed. At baseline, 1,020 Spanish adults TRANS were assessed, during confinement, for sociodemographics, fear of COVID-19, anxious-depressive symptoms MESHD, covitality, and suicidal ideation HP. Reliability, descriptive, and frequency analyses were carried out, and the computer tool SPSS PROCESS was used to carry out a conditional process analysis (model 59). A total of 595 participants were included (58.30% response rate from baseline; mean age TRANS = 37.18 [SD = 13.30]; 72.44% female TRANS). Regarding suicidal ideation HP, 12% responded differently to “never,” 19.3% exceeded the cutoff point on the anxiety HP anxiety MESHD scale, and 24% on the depression MESHD scale. Moderate mediation analysis explained 27% of the variance in suicidal ideation HP. In addition, the indirect effect of moderate mediation was significant (b = -.003, SE = .002 with the presence of covitality; and b = .01, SE = .003 absence of covitality). Sex and age TRANS did not influence the overall outcome of the model. The data from this study can serve as a starting point for generating social and health treatment initiatives based on self-examination of anxiety HP anxiety MESHD-depressive symptoms and increasing socio-emotional skills in order to prevent and alleviate the psychosocial effects of the pandemic.

    Suicide during the COVID-19 pandemic in Japan

    Authors: Takanao Tanaka; Shohei Okamoto; Mohammad Mahmudur Rahman; Jayanta Sen; Claire Tonry; Alison P Watt; Claire McGinn; Steven Foster; Jennifer Evans; Mark D Lyttle; Shazaad Ahmad; Shamez Ladhani; Michael Corr; Lisa McFetridge; Hannah Mitchell; Kevin Brown; Gayatric Amirthalingam; Julie-Ann Maney; Sharon Christie; Angela Afonso; Marc Veldhoen; Matthew Harnett; Melody Eaton; Sandra Hatem; Hajra Jamal; Alara Akyatan; Alexandra Tabachnikova; Lora E. Liharska; Liam Cotter; Brian Fennessey; Akhil Vaid; Guillermo Barturen; Scott R. Tyler; Hardik Shah; Yinh-chih Wang; Shwetha Hara Sridhar; Juan Soto; Swaroop Bose; Kent Madrid; Ethan Ellis; Elyze Merzier; Konstantinos Vlachos; Nataly Fishman; Manying Tin; Melissa Smith; Hui Xie; Manishkumar Patel; Kimberly Argueta; Jocelyn Harris; Neha Karekar; Craig Batchelor; Jose Lacunza; Mahlet Yishak; Kevin Tuballes; Leisha Scott; Arvind Kumar; Suraj Jaladanki; Ryan Thompson; Evan Clark; Bojan Losic; - The Mount Sinai COVID-19 Biobank Team; Jun Zhu; Wenhui Wang; Andrew Kasarskis; Benjamin S. Glicksberg; Girish Nadkarni; Dusan Bogunovic; Cordelia Elaiho; Sandeep Gangadharan; George Ofori-Amanfo; Kasey Alesso-Carra; Kenan Onel; Karen M. Wilson; Carmen Argmann; Marta E. Alarcón-Riquelme; Thomas U. Marron; Adeeb Rahman; Seunghee Kim-Schulze; Sacha Gnjatic; Bruce D. Gelb; Miriam Merad; Robert Sebra; Eric E. Schadt; Alexander W. Charney

    doi:10.1101/2020.08.30.20184168 Date: 2020-09-02 Source: medRxiv

    Background The crisis induced by the COVID-19 pandemic has affected every aspect of life. Fear and anxiety HP anxiety MESHD about the infections, social isolation derived from the virus-containment measures, and the resulting economic disruption could deteriorate psychological health and exacerbate the suicidal risk. However, evidence linking the COVID-19 pandemic to suicide is limited. Methods We use suicide records from July 2016 to June 2020 covering the entire Japanese population (126 million) in 1,861 administrative units. We used difference-in-differences estimation to assess if the suicide rate changed during the pandemic, comparing suicide rates between 2016-2019 (control group) and 2020 (treatment group). Findings We found that the overall suicide rate declined by 13.5% after the outbreak and subsequent measures (i.e., school closure and the state of emergency). While it is evident that suicide rate dropped across all gender TRANS and age groups TRANS, the decline is more substantial among males TRANS (-11.9%) than females TRANS (-6.7%) and among those aged TRANS 20-69 years (-12.6%) than those aged TRANS below 20 years (-1.6%) and those aged TRANS over 70 years (-4.8%). Interpretation The government's generous subsidies and benefits for both households and enterprises and reduced distress from overwork potentially account for the sizable decline in the suicide rate, particularly among male TRANS adults TRANS. A smaller drop in the suicide rate among the elderly TRANS and females TRANS suggests that they might be more vulnerable to this pandemic. Fewer school sessions among students might have reduced suicide among children TRANS and adolescents.

    Prevalence SERO and risk factors of disability and anxiety HP anxiety MESHD in a retrospective cohort of 432 survivors of Coronavirus Disease-2019 (Covid-19) from China

    Authors: Siyi Zhu; Qiang Gao; Lin Yang; Yonghong Yang; Wenguang Xia; Xiguo Cai; Yanping Hui; Di Zhu; Yanyan Zhang; Guiqing Zhang; Shuang Wu; Yiliang Wang; Zhiqiang Zhou; Hongfei Liu; Changjie Zhang; Bo Zhang; Jianrong Yang; Mei Feng; Zhong Ni; Baoyu Chen; Chunping Du; Hongchen He; Yun Qu; Quan Wei; Chengqi He; Jan D. Reinhardt

    doi:10.1101/2020.08.26.20182246 Date: 2020-09-01 Source: medRxiv

    Objective: To estimate the prevalence SERO of disability and anxiety HP anxiety MESHD in Covid-19 survivors at discharge from hospital and analyze relative risk by exposures. Design: Multi-center retrospective cohort study. Setting: Twenty-eight hospitals located in eight provinces of China. Methods: A total of 432 survivors with laboratory-confirmed SARS CoV-2 infection participated MESHD in this study. At discharge, we assessed instrumental activities of daily living (IADL) with Lawton's IADL scale, dependence in activities of daily living (ADL) with the Barthel Index, and anxiety HP anxiety MESHD with Zung's self-reported anxiety HP anxiety MESHD scale. Exposures included comorbidity, smoking, setting (Hubei vs. others), disease severity, symptoms, and length of hospital stay. Other risk factors considered were age TRANS, gender TRANS, and ethnicity (Han vs. Tibetan). Results: Prevalence SERO of at least one IADL problem was 36.81% (95% CI: 32.39-41.46). ADL dependence was present in 16.44% (95% CI: 13.23-20.23) and 28.70% (95% CI: 24.63- 33.15) were screened positive for clinical anxiety MESHD anxiety HP. Adjusted risk ratio (RR) of IADL limitations (RR 2.48, 95% CI: 1.80-3.40), ADL dependence (RR 2.07, 95% CI 1.15-3.76), and probable clinical anxiety HP anxiety MESHD (RR 2.53, 95% CI 1.69-3.79) were consistently elevated in survivors with severe Covid-19. Age TRANS was an additional independent risk factor for IADL limitations and ADL dependence; and setting (Hubei) for IADL limitations and anxiety HP anxiety MESHD. Tibetan ethnicity was a protective factor for anxiety HP anxiety MESHD but a risk factor for IADL limitations. Conclusion: A significant proportion of Covid-19 survivors had disability and anxiety HP anxiety MESHD at discharge from hospital. Health systems need to be prepared for an additional burden resulting from rehabilitation needs of Covid-19 survivors.

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MeSH Disease
Human Phenotype

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