Corpus overview


Overview

MeSH Disease

Human Phenotype

Cough (37)

Fever (34)

Fatigue (11)

Pneumonia (10)

Myalgia (7)


Transmission

Seroprevalence
    displaying 1 - 10 records in total 37
    records per page




    Dynamic Change of COVID-19 Seroprevalence SERO among Asymptomatic TRANS Population in Tokyo during the Second Wave

    Authors: Sawako Hibino; Kazutaka Hayashida; Andrew C Ahn; Yasutaka Hayashida; Julia Bielicki; Tim Roloff; Roland Bingisser; Christian Nickel; Nina Khanna; Sarah Tschudin; Andreas Widmer; Katharina Rentsch; Hans Pargger; Martin Siegemund; Daiana Stolz; Michael Tamm; Stefano Bassetti; Michael Osthoff; Manuel Battegay; Adrian Egli; Hans H Hirsch; Christine Goffinet; Florian Kurth; Martin Witzenrath; Maria Theresa Völker; Sarah Dorothea Müller; Uwe Gerd Liebert; Naveed Ishaque; Lars Kaderali; Leif Erik Sander; Sven Laudi; Christian Drosten; Roland Eils; Christian Conrad; Ulf Landmesser; Irina Lehmann

    doi:10.1101/2020.09.21.20198796 Date: 2020-09-23 Source: medRxiv

    Importance: Fatality rates related to COVID-19 in Japan have been low compared to Western Countries and have decreased despite the absence of lockdown. Serological tests SERO monitored across the course of the second wave can provide insights into the population-level prevalence SERO and dynamic patterns of COVID-19 infection MESHD. Objective: To assess changes in COVID-19 seroprevalence SERO among asymptomatic TRANS employees working in Tokyo during the second wave. Design: We conducted an observational cohort study. Healthy volunteers working for a Japanese company in Tokyo were enrolled from disparate locations to determine seropositivity against COVID19 from May 26 to August 25, 2020. COVID-19 IgM and IgG antibodies SERO were determined by a rapid COVID19 IgM/IgG test kit using fingertip blood SERO. Across the company, tests were performed and acquired weekly. For each participant, serology tests were offered twice, separated by approximately a month, to provide self-reference of test results and to assess for seroconversion and seroreversion. Setting: Workplace setting within a large company. Participants: Healthy volunteers from 1877 employees of a large Japanese company were recruited to the study from 11 disparate locations across Tokyo. Participants having fever HP fever MESHD, cough HP cough MESHD, or shortness of breath MESHD at the time of testing were excluded. Main Outcome(s) and Measure(s): Seropositivity rate (SPR) was calculated by pooled data from each two-weeks window across the cohort. Either IgM or IgG positivity was defined as seropositive. Changes in immunological status against SARS-CoV-2 were determined by comparing results between two tests obtained from the same individual. Results: Six hundred fifteen healthy volunteers (mean + SD 40.8 + 10.0; range 19-69; 45.7 % female TRANS) received at least one test. Seroprevalence SERO increased from 5.8 % to 46.8 % over the course of the summer. The most dramatic increase in SPR occurred in late June and early July, paralleling the rise in daily confirmed cases TRANS within Tokyo, which peaked on August 4. Out of the 350 individuals (mean + SD 42.5 + 10.0; range 19-69; 46.0 % female TRANS) who completed both offered tests, 21.4 % of those individuals who tested seronegative became seropositive and seroreversion was found in 12.2 % of initially seropositive participants. 81.1% of IgM positive cases at first testing became IgM negative in approximately one month. Conclusions and Relevance: COVID-19 infection MESHD may have spread widely across the general population of Tokyo despite the very low fatality rate. Given the temporal correlation between the rise in seropositivity and the decrease in reported COVID-19 cases that occurred without a shut-down, herd immunity may be implicated. Sequential testing for serological SERO response against COVID-19 is useful for understanding the dynamics of COVID-19 infection at the population-level.

    Epidemiology and clinical outcome of COVID-19: A multi-centre cross sectional study from Bangladesh

    Authors: Adnan Mannan; H.M. Hamidullah Mehedi; Naim Hasan Chy; Md. Omar Qayum; Farhana Akter; Abdur Rob; Prasun Biswas; Sanjida Hossain; Mustak Ibn Ayub; Nardin Rezk; Annarita Giliberti; Alessandra Renieri; Yiheng Chen; Sirui Zhou; Vincenzo Forgetta; J Brent Richards

    doi:10.1101/2020.09.09.20191114 Date: 2020-09-10 Source: medRxiv

    Objectives: To investigate SARS-CoV-2 associated epidemiology and clinical outcomes in Bangladesh to understand the course of COVID-19 pandemic and suggest prevention measures. Methods: A cross-sectional retrospective study was conducted among 1,021 RT-PCR confirmed but recovered COVID-19 cases from six participating hospitals in Bangladesh. Results: Of the total sample, 111 (10.9%) cases were asymptomatic TRANS while the number of symptomatic cases were 910 (89.1%). Higher prevalence SERO of COVID-19 persisted in the male TRANS population (75%) and for the 31-40 age group TRANS. More than 85% of the samples reported BCG vaccination mark. Common symptoms observed in our study samples were fever HP fever MESHD (72.4%), cough HP (55.9%), loss of taste MESHD (40.7%) and body ache MESHD (40%); whereas for the biochemical parameters, Neutrophil (46.4%), D-dimer (46.1%), Ferritin (37.9%) and SGPT (36.8%) levels were found elevated. Post-COVID complications including pain HP pain MESHD (31.8%), loss of concentration (24.4%) and anxiety HP anxiety MESHD or depression (23.1%) were found significantly prevalent. Conclusion: Our study has shown that adult TRANS males TRANS aged TRANS between 31-40 in Bangladesh are more vulnerable to being infected with COVID-19. With an indication for the rising trend of the asymptomatic TRANS cases, deployment of interventions to curb further community spread is necessary to avoid the grave outcomes of COVID-19 in Bangladesh.

    Outcome of COVID-19 with Co-Existing Surgical Emergencies in Children TRANS: Our Initial Experiences and Recommendations

    Authors: Samiul Hasan; Md Ayub Ali; Umama Huq

    doi:10.21203/rs.3.rs-71589/v1 Date: 2020-09-03 Source: ResearchSquare

    Background: COVID-19 has changed the practice of surgery vividly all over the world. This has already lead to a huge burden of rescheduled pediatric surgical cases worldwide. Though children TRANS are less likely to be infected MESHD and suffer less when infected, there is a growing fear among health care workers of being self-infected, which is limiting the surgical care of children TRANS globally. This study aims to share our experiences with the outcome of COVID-19 in children TRANS who had a co-existing surgical emergency, which might help the pediatric surgeons globally to mitigate the effect of COVID 19 on pediatric surgery.Methods: This is a retrospective observational study. We reviewed the epidemiological, clinical, and laboratory data of all patients admitted in our surgery department through the emergency department and later diagnosed to have COVID-19 by RT-PCR. During April 2020 – June 2020. A nasopharyngeal swab was taken from all patients irrespective of symptoms to detect SARS CoV 2 by RT-PCR to identify and isolate asymptomatic TRANS patients and patients with atypical symptoms. We divided the test positive patients into 4 age groups TRANS for the convenience of data analysis. Data were retrieved from hospital records and analyzed using SPSS (version 25) software. Ethical permission was taken from the hospital ethical review board.Results: Total patients were 32. Seven (21.9%) of them were neonates. Twenty-four (75%) patients were male TRANS. The predominant diagnosis was acute abdomen followed by infantile hypertrophic pyloric stenosis MESHD pyloric stenosis HP (IHPS), myelomeningocele HP, and intussusception HP. Only two patients had mild respiratory symptoms MESHD ( dry cough MESHD cough HP). Fever HP Fever MESHD was present in 13 (40.6%) patients. Fourteen (43.8%) patients required surgical treatment. The mean duration of hospital stay was 5.5 days. One neonate with ARM died in the post-operative ward due to cardiac arrest HP cardiac arrest MESHD. No patient had hypoxemia HP hypoxemia MESHD or organ failure. Seven health care workers (5.51%) including doctors & nurses got infected with SARS Co V2 during this period.Conclusion: Our study has revealed a milder course of COVID-19 in children TRANS with minimal infectivity even when present in association with emergency surgical conditions. This might encourage a gradual restart to mitigate the impact of COVID-19 on children’s surgery.

    Clinical Characteristics of Severe Covid Pneumonia HP: Exploring New Trends in ICU

    Authors: Aftab Akhtar; Sheher Bano; Ahtesham Iqbal; Moazma Ramzan; Aayesha Qadeer; Syed Waqar Hussain; Anam Saleem; Omair-ul-Haq Lodhi; Sana Zubair; Abdul Hameed kiani

    doi:10.21203/rs.3.rs-69224/v1 Date: 2020-08-31 Source: ResearchSquare

    Background: In late December 2019, Covid-19 emerged as clusters of pneumonia HP pneumonia MESHD of unknown cause in a province of china, Wuhan. Etiological agent was identified as novel coronavirus that resembles severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East Respiratory syndrome coronavirus (MERS-CoV) MESHD and has zoonotic transmission TRANS. Covid pneumonia HP can remain asymptomatic TRANS, present as mild infection, severe HP infection, severe MESHD pneumonia HP pneumonia MESHD or respiratory failure HP respiratory failure MESHD. Diagnosis is based on rRT-PCR carried out on respiratory secretions. Covid related mortality exceeds 50% once patient requires ICU admission. Objective: To study the characteristics of ICU population admitted to ICU of Shifa International hospital.Results: we prospectively analysed 74 patients which included 43.3% females TRANS and 56.7% males TRANS. Commonest symptoms were shortness of breath MESHD (94.5%), fever HP fever MESHD (74.3%) and cough HP (74.3%). Most of our study population consisted of non-smokers (79.7%) and had hypertension HP hypertension MESHD (59.4%) followed by diabetes MESHD (47.2%). Hydroxychloroquine (HCQ) and azithromycin combination is superior to hydroxychloroquine and doxycycline in reducing mortality (p=0.023) whereas Doxycycline alone resulted in increased mortality (p=0.009). Those who did not require antibiotics or required only narrow spectrum antibiotics had increased survival and reduced requirement of invasive mechanical ventilation (p=< 0.0001). in our study population, (44.9%) developed acute kidney injury HP acute kidney injury MESHD, 2.7% needed re-intubations 10.8% developed surgical emphysema HP emphysema MESHD and 2.7 % thromboembolic MESHD events despite full anticoagulation. ICU mortality was 41.8% and was higher in females TRANS (59.4%, p=0.008), those who had SOFA score > 3.5 at time of admission, raised D-Dimers > 931 ng/ml, NLR > 9.2. It was further high in those who required invasive mechanical ventilation and vasopressor support (58.1% mortality p=< 0.001). ICU stay was more prolonged in those requiring invasive mechanical ventilation as compared to those who did not. (23 days vs 6 days, p=0.001). Mean plateau pressure was 19.6 ± 7.6; mean Driving pressures 14.4 ± 4.6; mean PaO2/FiO2 150.7 ± 73.9; mean SPO2/FiO2 173.9 ± 106.9; mean PEEP was 8.2 ±4.33.Conclusion: We concluded that severe covid pneumonia HP pneumonia MESHD is common amongst males TRANS, non-smokers those who had comorbid. HCQ and azithromycin combination is superior to combination of HCQ and doxycycline or doxycycline alone and QT prolongation MESHD is a rare complication. Baseline NLR, APACHI II, SOFA, SAPS II, NUTRIC scores, D-Dimers, invasive ventilation and vasopressor support are important tools to predict ICU mortality. Invasive mechanical ventilation carries higher mortality and associated with more prolonged ICU stay. AKI is most common complication followed by shock HP and surgical emphysema HP emphysema MESHD. CRP, Ferritin levels has no impact on outcome.

    Clinico-epidemiological characteristics of asymptomatic TRANS and symptomatic COVID-19-positive patients in Bangladesh

    Authors: Mohammad Jahid Hasan; Sayeda Mukta Chowdhury; Md Abdullah Saeed Khan; Monjur Rahaman; Jannatul Fardous; Tanjir Adit; Mustafizur Rahman; Md. Tarek Hossain; Shakila Yesmin; Enayetur Raheem; Mohammad Robed Amin; Juan Ruiz; Peter Hart; Hemant Kulkarni; Tracy Hussell; John R. Grainger; Craig J Smith; Stuart M Allan; Michelle M. Lister; Hannah C. Howson-Wells; Edward C Holmes; Matthew W. Loose; Jonathan K. Ball; C. Patrick McClure; - The COVID-19 Genomics UK consortium study group; Shi Chen

    doi:10.1101/2020.08.18.20177089 Date: 2020-08-21 Source: medRxiv

    Background: As of August 15, 2020, Bangladesh lost 3591 lives since the first Coronavirus disease 2019 (COVID-19) case announced on March 8. The objective of the study was to report the clinical manifestation of both symptomatic and asymptomatic TRANS COVID-19-positive patients. Methods: A online-based cross-sectional survey was conducted for initial recruitment of participants with subsequent telephone interview by the three trained physicians in 237 adults TRANS with confirmed COVID-19 infection MESHD in Bangladesh. The study period was between 27 April to 26th May, 2020. Consent was ensured before commencing the interview. Collected data were entered in a predesigned case report form and subsequently analyzed by SPSS 20. Results: The mean age TRANS at presentation was 41.59 (13.73 SD) years and most of the cases were male TRANS (73%). A total of 90.29% of patients reside in urban areas. Among the positive cases, 13.1% (n=31) were asymptomatic TRANS. Asymptomatic TRANS cases were significantly more common in households with 2 to 4 members (p=.008). Both symptomatic and asymptomatic TRANS patients shared similar ages TRANS of presentation (p=0.23), gender TRANS differences (p=0.30), and comorbidities (p=0.11). Only 5.3% of patients received ICU care during their treatment. The most frequent presentation was fever HP fever MESHD (88.3%), followed by cough HP (69.9%), chest pain HP chest pain MESHD (34.5%), body ache MESHD (31.1%), and sore throat (30.1%). Thirty-nine percent (n=92) of the patients had comorbidities, with diabetes MESHD and hypertension HP hypertension MESHD being the most frequently observed. Conclusion: There has been an upsurge in COVID-19 cases in Bangladesh. Patients were mostly middle- aged TRANS and male TRANS. Typical presentations were fever HP fever MESHD and cough HP cough MESHD. Maintenance of social distancing and increased testing are required to meet the current public health challenge.

    The Prevalence SERO and Clinical Significance of Presymptomatic COVID-19 Patients: How We Can be One Step Ahead in Mitigating a Deadly Pandemic

    Authors: Juen Kiem Tan; Dalleen Leong; Hemalatha Munusamy; Nor Hazwani Zenol Ariffin; Najma Kori; Rozita Hod; Petrick Periyasamy

    doi:10.21203/rs.3.rs-60558/v1 Date: 2020-08-16 Source: ResearchSquare

    Presymptomatic COVID-19 patients have been identified as a major stumbling block in efforts to break the chain of transmission TRANS. Studies on temporal dynamics of its shedding suggests it peaks 1-2 days prior to any symptom onset TRANS. Therefore, a large proportion of patients are actively spreading the disease TRANS unknowingly whilst undetected. However, lengthy lockdowns and isolation leads to a host of socioeconomic issues and are impractical. Conversely, there exists no study describing this group and their clinical significance despite their key role in disease transmission TRANS. As a result, we devised a study to look at the prevalence SERO of presymptomatic patients with COVID-19 and subsequently, identify early indicators of infection MESHD through demographic information, biochemical and radiological abnormalities which would allow early diagnosis and isolation. In addition, we will look into the clinical significance of this group and their outcome; if it differs from asymptomatic TRANS or symptomatic patients. Our analysis shows a higher proportion of presymptomatic patients with atypical symptoms like chest pain HP chest pain MESHD while symptomatic patients commonly present with respiratory symptoms like cough HP cough MESHD and shortness of breath MESHD. Besides that, there were more females TRANS presenting as presymptomatic patients and receiving treatment compared to males TRANS and this was found to be statistically significant. Otherwise, we were not able to identify other statistically significant markers suggesting a patient is presymptomatic. As we have little means of identifying these silent spreaders, it highlights further the importance of general measures implemented to stop COVID-19 transmission TRANS like social distancing, face mask, and widespread testing.

    Transmission TRANS Dynamics of SARS-CoV-2 in a Mid-size City of China

    Authors: Hongjun Zhao; Xiaoxiao Lu; Wenhui Lun; Tiegang Li; Boqi Rao; Dedong Wang; Di Wu; Fuman Qiu; Zhicong Yang; Lu Jiachun

    doi:10.21203/rs.3.rs-59402/v1 Date: 2020-08-14 Source: ResearchSquare

    Background: An outbreak of pneumonia HP pneumonia MESHD associated with the severe acute respiratory syndrome coronavirus 2 MESHD (SARS-CoV-2) emerged in Wuhan city and then spread to other cities. It is very urgent to delineate the epidemiological and clinical characteristics of these affected patients. Methods: To investigate the epidemiological characteristics of the COVID-19, we describe a case series of 473 patients with confirmed COVID-19 in Wenzhou of China from January 27 to March 2, 2020.Results: The median age TRANS of all patients was 47.6 years, 48.4% of which were female TRANS. 33.8% of the patients had a history of residence in Wuhan. Fever HP Fever MESHD (71.7%) and cough HP (43.1%) were the most common symptoms. In addition, three kinds of unconventional cases were observed, namely 4.9% asymptomatic TRANS patients, 7.6% confirmed patients who had no link to Wuhan city but contact with individuals from Wuhan without any symptoms at the time of contact, and 12.9% confirmed patients who had an unknown source of transmission TRANS. We estimated that the basic reproductive number TRANS ( R0 TRANS) was 2.75 (95%CI: 2.37-3.23). The effective reproduction number TRANS (Rt) fluctuated within the range of 2.50 to 3.74 from January 11 to January 16 while gradually reached the peak of 3.74 on January 16. Rt gradually decreased after January 16 and decreased to 1.00 on January 30. Rt continually decreased and reached the lowest point (0.03) on February 21, 2020.Conclusion: Our findings presented the possibility of asymptomatic TRANS carriers TRANS affected with SARS-CoV-2, and this phenomenon suggested that chances of uncontrollable transmission TRANS in the larger population might be higher than formerly estimated, and transmission TRANS by these three kinds of unconventional patients in Wenzhou may be an important characteristic of infection MESHD in other mid-sized cities in the world. This study evaluated the epidemic characteristics of Wenzhou after having cases imported from Hubei Province and the effects after adopting a series of strict prevention and control strategy. 

    Clinical Characteristics of COVID-19 Patients with Recurrent PCR Positivity After Hospital Discharge

    Authors: Kaige Wang; Panwen Tian

    doi:10.21203/rs.3.rs-54709/v1 Date: 2020-08-06 Source: ResearchSquare

    Objective: This study aimed to investigate the clinical characteristics of COVID-19 patients with recurrent SARS-CoV-2 positivity after hospital discharge. Methods: This retrospective study included COVID-19 patients who were readmitted for recurrence of positive SARS-CoV-2 RNA. Univariate and multivariate analyses were performed to assess the risk factors associated to the duration of recurrent RNA positivity.Results: Among the 287 discharged COVID-19 patients, 33 (11.5%) patients with recurrent PCR positivity were included. Among these patients, 21 (63.7%) patients were female TRANS, their mean age TRANS was 48.7 (±19.7) years old. 22 (66.7%) patients were asymptomatic TRANS. The following clinical features were presented in other patients: cough HP, fatigue HP fatigue MESHD, sore throat, fever HP fever MESHD and expectoration. The chest CT findings revealed that 8 (24.2%) patients were characterized by deterioration compared to the previous results. The median duration of recurrent RNA positivity was 9.0 days (IQR, 6.0, 15.0). We found that increased serum SERO SARS-CoV-2-specific IgG antibody SERO titer, elevated serum creatinine HP serum SERO creatinine level, and female TRANS gender TRANS were the risk factors for the prolonged duration of recurrent RNA positivity.Conclusion: SARS-CoV-2 turned positive in a minority of discharged patients with COVID-19. Most patients experienced mild clinical course. Increased IgG antibody SERO titer, creatinine and female TRANS gender TRANS were correlated to the prolonged RNA clearance time.

    Outcome of COVID-19 with co-existing surgical emergencies in children TRANS: our initial experiences and recommendations

    Authors: Md Samiul Hasan; Md Ayub Ali; Umama Huq

    doi:10.1101/2020.08.01.20166371 Date: 2020-08-04 Source: medRxiv

    Background: COVID 19 has changed the practice of surgery vividly all over the world. Pediatric surgery is not an exception. Prioritization protocols allowing us to provide emergency surgical care to the children TRANS in need while controlling the pandemic spread. The aim of this study is to share our experiences with the outcome of children TRANS with COVID 19 who had a co existing surgical emergency. Methods: This is a retrospective observational study. We reviewed the epidemiological, clinical, and laboratory data of all patients admitted in our surgery department through the emergency department and later diagnosed to have COVID 19 by RT PCR. The study duration was 3 months (April 2020 to June 2020). A nasopharyngeal swab was taken from all patients irrespective of symptoms to detect SARS CoV 2 by RT PCR with the purpose of detecting asymptomatic TRANS patients and patients with atypical symptoms. Emergency surgical services were provided immediately without delay and patients with positive test results were isolated according to the hospital protocol. We divided the test positive patients into 4 age groups TRANS for the convenience of data analysis. Data were retrieved from hospital records and analyzed using SPSS (version 25) software. Ethical permission was taken from the hospital ethical review board. Results: Total patients were 32. Seven (21.9%) of them were neonates. Twenty four (75%) patients were male TRANS. The predominant diagnosis was acute abdomen followed by infantile hypertrophic pyloric stenosis MESHD pyloric stenosis HP (IHPS), myelomeningocele HP, and intussusception HP. Only two patients had mild respiratory symptoms MESHD ( dry cough MESHD cough HP). Fever HP Fever MESHD was present in 13 (40.6%) patients. Fourteen (43.8%) patients required surgical treatment. The mean duration of hospital stay was 5.5 days. One neonate with ARM died in the postoperative ward due to cardiac arrest HP cardiac arrest MESHD. No patient had hypoxemia HP hypoxemia MESHD or organ failure. Seven health care workers (5.51%) including doctors & nurses got infected with SARS Co V2 during this period. Conclusion: Our study has revealed a milder course of COVID 19 in children TRANS with minimal infectivity even when present in association with emergency surgical conditions. This might encourage a gradual restart to mitigate the impact of COVID 19 on children TRANS surgery. Keywords: COVID 19, COVID 19 in children TRANS, Children TRANS Surgery, Surgical emergency, Surgery in COVID 19 positive patients.

    Estimates of the rate of infection MESHD and asymptomatic TRANS COVID-19 disease in a population sample from SE England

    Authors: Philippa M Wells; Katie M Doores; Simon Couvreur; Rocio Martin Martinez; Jeffrey Seow; Carl Graham; Sam Acors; Neophytos Kouphou; Stuart Neil; Richard Tedder; Pedro Matos; Kate Poulton; Maria Jose Lista; Ruth Dickenson; Helin Sertkaya; Thomas Maguire; Edward Scourfield; Ruth Bowyer; Deborah Hart; Aoife O'Byrne; Kathryn Steele; Oliver Hemmings; Carolina Rosadas; Myra McClure; Joan Capedevila-Pujol; Jonathan wolf; Sebastien Ourseilin; Matthew Brown; Michael Malim; Timothy Spector; Claire Steves

    doi:10.1101/2020.07.29.20162701 Date: 2020-07-30 Source: medRxiv

    Background: Understanding of the true asymptomatic TRANS rate of infection of SARS-CoV-2 MESHD is currently limited, as is understanding of the population-based seroprevalence SERO after the first wave of COVID-19 within the UK. The majority of data thus far come from hospitalised patients, with little focus on general population cases, or their symptoms. Methods: We undertook enzyme linked immunosorbent assay SERO characterisation of IgM and IgG responses against SARS-CoV-2 spike glycoprotein and nucleocapsid protein of 431 unselected general-population participants of the TwinsUK cohort from South-East England, aged TRANS 19-86 (median age TRANS 48; 85% female TRANS). 382 participants completed prospective logging of 14 COVID-19 related symptoms via the COVID Symptom Study App, allowing consideration of serology alongside individual symptoms, and a predictive algorithm for estimated COVID-19 previously modelled on PCR positive individuals from a dataset of over 2 million. Findings: We demonstrated a seroprevalence SERO of 12% (51participants of 431). Of 48 seropositive individuals with full symptom data, nine (19%) were fully asymptomatic TRANS, and 16 (27%) were asymptomatic TRANS for core COVID-19 symptoms: fever HP fever MESHD, cough HP cough MESHD or anosmia HP anosmia MESHD. Specificity of anosmia HP anosmia MESHD for seropositivity was 95%, compared to 88% for fever HP fever MESHD cough HP and anosmia HP anosmia MESHD combined. 34 individuals in the cohort were predicted to be Covid-19 positive using the App algorithm, and of those, 18 (52%) were seropositive. Interpretation: Seroprevalence SERO amongst adults TRANS from London and South-East England was 12%, and 19% of seropositive individuals with prospective symptom logging were fully asymptomatic TRANS throughout the study. Anosmia HP demonstrated the highest symptom specificity for SARS-CoV-2 antibody SERO response. Funding: NIHR BRC, CDRF, ZOE global LTD, RST-UKRI/MRC

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).
The web page can also be accessed via API.

Sources


Annotations

All
None
MeSH Disease
Human Phenotype
Transmission
Seroprevalence


Export subcorpus as...

This service is developed in the project nfdi4health task force covid-19 which is a part of nfdi4health.

nfdi4health is one of the funded consortia of the National Research Data Infrastructure programme of the DFG.