Corpus overview


Overview

MeSH Disease

Disease (1)


Human Phenotype

There are no HP terms in the subcorpus


Transmission

There are no transmission terms in the subcorpus


Seroprevalence
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    SARS-CoV-2 Seroprevalence SERO Among Parturient Women

    Authors: Dustin D. Flannery; Sigrid Gouma; Miren B. Dhudasia; Sagori Mukhopadhyay; Madeline R. Pfeifer; Emily C. Woodford; Jeffrey S. Gerber; Claudia P. Arevalo; Marcus J. Bolton; Madison E. Weirick; Eileen C. Goodwin; Elizabeth M. Anderson; Allison R. Greenplate; Justin Kim; Nicholas Han; Ajinkya Pattekar; Jeanette Dougherty; Oliva Kuthuru; Divij Mathew; Amy E. Baxter; Laura A. Vella; JoEllen Weaver; Anurag Verma; Rita Leite; Jeffrey S. Morris; Daniel J. Rader; Michal A. Elovitz; E. John Wherry; Karen M. Puopolo; Scott E. Hensley

    doi:10.21203/rs.3.rs-27402/v1 Date: 2020-05-07 Source: ResearchSquare

    SARS-CoV-2 has led to a pandemic of respiratory and multisystem disease MESHD, named COVID-19.1 Limited data are available for pregnant women affected by COVID-19.2 Serological tests SERO, particularly those that provide quantitative information, are critically important to determine exposure and immunity to SARS-CoV-2 within both individuals and populations.3 Here, we completed SARS-CoV-2 serological testing SERO of 237 parturient women at two centers in Philadelphia from April 4 to April 15, 2020. Using an assay with a 1.0% false positive rate, we show that 14/237 (5.9%) of parturient women possessed IgG and/or IgM SARS-CoV-2-specific antibodies SERO. We found significant racial differences, with an 11.2% seropositive rate in black women and a 1.5% seropositive rate in women of other races. Seropositive women who received nasopharyngeal (NP) SARS-CoV-2 PCR (polymerase chain reaction) testing were all found to be positive. Continued serologic surveillance among pregnant women may inform perinatal clinical practices and can potentially be used to estimate seroprevalence SERO within the community.Authors Dustin D. Flannery and Sigrid Gouma contributed equally to this work.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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