Corpus overview


MeSH Disease

HGNC Genes

SARS-CoV-2 proteins

ProteinE (1)


SARS-CoV-2 Proteins
    displaying 1 - 1 records in total 1
    records per page

    SARS-COV2 Envelope Protein (E PROTEIN) interacts with the Lysophosphatidic Acid Receptor 1 HGNC ( LPAR1 HGNC) from humans

    Authors: GIRISH NALLUR

    doi:10.21203/ Date: 2020-07-13 Source: ResearchSquare

    A proteomic screen of human proteins interacting with the SARS-COV2 Envelope (E) protein PROTEIN identified LPAR1 HGNC as a strong candidate. Physical association of E protein PROTEIN and LPAR1 HGNC was confirmed by co-immunoprecipitation and cell surface staining. LPAR1 HGNC- E protein PROTEIN interaction was confirmed in all eight human cell lines tested. Many additional proteins participating in the E protein PROTEIN interactions network were also enriched from each of the cell lines, some of which were cell type specific. These findings suggest that LPAR1 HGNC is likely a cell surface receptor for the E protein PROTEIN, and pave the way for follow-on studies aimed at understanding the biological significance of the interactions in SARS-COV disease MESHD, including the signaling mechanisms.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from and is updated on a daily basis (7am CET/CEST).
The web page can also be accessed via API.



MeSH Disease
HGNC Genes
SARS-CoV-2 Proteins

Export subcorpus as...

This service is developed in the project nfdi4health task force covid-19 which is a part of nfdi4health.

nfdi4health is one of the funded consortia of the National Research Data Infrastructure programme of the DFG.