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MeSH Disease

Human Phenotype

Transmission

Seroprevalence
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    CT Imaging Changes of Corona Virus Disease MESHD 2019 (COVID-19):A multi-center study in Southwest China

    Authors: Xiaoming Li; Wenbing Zeng; Xiang Li; Haonan Chen; Linping Shi; Xinghui Li; Hongnian Xiang; Yang Cao; Hui Chen; Chen Liu; Jian Wang

    doi:10.21203/rs.3.rs-16974/v2 Date: 2020-03-09 Source: ResearchSquare

    Background: Since the first case of a coronavirus disease MESHD 2019 (COVID-19) infection pneumonia MESHD pneumonia HP was detected in Wuhan, China, a series of confirmed cases TRANS of the COVID-19 were found in Southwest China. The aim of this study was to describe the imaging manifestations of hospitalized patients with confirmed COVID-19 infection MESHD in southwest China. Methods: In this retrospective study, data were collected from 131 patients with confirmed coronavirus disease 2019 (COVID-19) from 3 Chinese hospitals. Their common clinical manifestations, as well as characteristics and evolvement features of chest CT images, were analyzed. Results: A total of 100 (76%) patients had a history of close contact TRANS with people living in Wuhan , Hubei. The clinical manifestations of COVID-19 included cough HP, fever HP. Most of the lesions identified in chest CT images were multiple lesions of bilateral lungs, lesions were more localized in the peripheral lung, 109 (83%) patients had more than two lobes involved,  20 (15%) patients presented with patchy ground glass opacities, patchy ground glass opacities and consolidation of lesions co-existing in 61 (47%) cases. Complications such as pleural thickening HP, hydrothorax, pericardial effusion HP, and enlarged mediastinal lymph nodes were detected but only in rare cases. For the follow-up chest CT examinations (91 cases), We found 66 (73%) cases changed very quickly, with an average of 3.5 days, 25 cases (27%) presented absorbed lesions, progression was observed in 41 cases (46%), 25 (27%) cases showed no significant changes. Conclusion: Chest CT plays an important role in diagnosing COVID-19. The imaging pattern of multifocal peripheral ground glass or mixed consolidation is highly suspicious of COVID-19, that can quickly change over a short period of time.

    Clinical characterization and chest CT findings in laboratory-confirmed COVID-19: a systematic review and meta-analysis

    Authors: Golnaz Vaseghi; Marjan Mansourian; Raheleh Karimi; Kiyan Heshmat-Ghahdarijani; Sadegh Baradaran Mahdavi; Amirhossein Pezeshki; Behrooz Ataei; Alireza Zandifar; Omid Shafaat; Shaghayegh Haghjoo Javanmard

    doi:10.1101/2020.03.05.20031518 Date: 2020-03-08 Source: medRxiv

    Background: Imagery techniques have been used as essential parts of diagnostic workup for patients suspected for 2019-nCoV infection MESHD, Multiple studies have reported the features of chest computed tomography (CT) scans among a number of 2019-nCoV patients. Method: Study Identification was carried out in databases (PubMed, Embase and Cochrane Library) to identify published studies examining the diagnosis, the 2019 novel coronavirus (2019-nCoV). Heterogeneity among reported prevalence SERO was assessed by computing p-values of Cochrane Q-test and I2-statics. The pooled prevalence SERO of treatment failure was carried out with a fixed effects meta-analysis model, generating the pooled 95% confidence interval. A random-effect model was used to pool the results since this model could incorporate the heterogeneity of the studies and therefore proved a more generalized result. Results: According to the combined results of meta-analysis, the total 55% of corona patients were males TRANS. The mean age TRANS of the patients was 41.31 (34.14, 48.47). Two prevalent clinical symptoms between patients were fever HP fever MESHD, cough HP cough MESHD with prevalence SERO of 85%, and 62%, respectively. Either Ground Glass Opacity GGO or consolidation was seen in 86% but 14% had NO GGO or consolidation. The other rare CT symptoms were pericardial effusion HP, and pleural effusion HP pleural effusion MESHD with 4, 5, 7% prevalence SERO, respectively. The most prevalent event was Either GGO or consolidation in 85% of patients. Conclusion: The most CT-scan abnormality is Either Ground Glass Opacity GGO or consolidation however in few patients none of them might be observed, so trusting in just CT findings will lead to miss some patients.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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