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MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Comparison of initial thin-section CT features in coronavirus disease MESHD 2019 pneumonia HP pneumonia MESHD and other community-acquired pneumonia HP pneumonia MESHD

    Authors: Qiao Zhu; Cui Ren; Xiao Hua Wang

    doi:10.21203/rs.3.rs-29838/v1 Date: 2020-05-19 Source: ResearchSquare

    Background Coronavirus disease MESHD 2019 (COVID-19) pneumonia HP pneumonia MESHD caused similar symptoms to other community-acquired pneumonia HP pneumonia MESHD (CAP). It is important to early quarantine suspected patients with COVID-19 pneumonia HP pneumonia MESHD from patients with other CAP to reduce cross infection MESHD. The purpose of the study is to review and compare initial thin-section computed tomography (CT) features in patients with coronavirus disease MESHD 2019 (COVID-19) pneumonia HP pneumonia MESHD and other community-acquired pneumonia HP pneumonia MESHD (CAP). Methods 24 cases of COVID-19 pneumonia HP pneumonia MESHD (14 males TRANS and 10 females TRANS; age TRANS range, 14-87 years; mean age TRANS, 48.0 years) and 28 cases of CAP caused by other pathogens (13 males TRANS and 15 females TRANS; age TRANS range, 24-85 years; mean age TRANS, 49.5 years) were included. Thin-section CT features of the lungs for all patients were retrospectively reviewed by two independent radiologists. Results There were no significant differences for the shape of main lesions, pure ground glass attenuation (GGA), mixed GGA with consolidation, air bronchogram, linear opacities, halo sign/reversed halo sign, cavitation and lymphadenopathy HP lymphadenopathy MESHD between the group of COVID-19 pneumonia HP pneumonia MESHD and the group of other CAP. However, the frequency of crazy-paving appearance, vessel dilatation HP, bilaterally involvement and peripherally distribution were significantly higher in patients with COVID-19 compared with other CAP ( p =0.031, p =0.000, p =0.029 and p =0.009, respectively). Conversely, the frequencies of pure consolidation, tree-in-bud sign and pleural effusion HP pleural effusion MESHD were significantly higher in patients with CAP than in patients with COVID-19 pneumonia HP pneumonia MESHD ( p =0.002, p =0.000 and p =0.048, respectively). Conclusion There are considerable overlaps in thin-section CT features between COVID-19 pneumonia HP pneumonia MESHD and other CAP. However, the presence of crazy paving pattern, vessel dilation, bilateral involvement and peripheral distribution contributes to the diagnosis of COVID-19 pneumonia HP pneumonia MESHD. While the presence of pure consolidation tree-in-bud sign, pleural effusion HP pleural effusion MESHD can be assisting in exclusive the diagnosis of COVID-19 pneumonia HP pneumonia MESHD.

    High Resolution Computed Tomography Finding in 552 Patients with Symptomatic COVID-19: First Report from North of Iran

    Authors: Hadi Majidi; Elham-Sadat Bani-Mostafavi; Zahra Mardanshahi; Farnaz Godazandeh; Roya Gasemian; Keyvan Heydari; Reza Alizadeh-Navaei

    doi:10.21203/rs.3.rs-25817/v1 Date: 2020-04-27 Source: ResearchSquare

    Purpose: Due to the emergence of the new Coronavirus-2019 and the lack of sufficient information about infected patients, this study was conducted to investigate the Chest High Resolution Computed Tomography (HRCT) findings of patients infected with the new Coronavirus 2019.Methods: This cross-sectional study was performed on COVID-19 patients referred to Medical Imaging Centers of Sari, Mazandaran, Iran, on March 2020 for Computed Tomography Scan (CT-Scan). Symptomatic patients were referred to the Medical Imaging Center for diagnosis confirmation through CT-scan. In addition to age TRANS and sex, HRCT findings were collected from the picture archiving and communication system (PACS) for further evaluations.Results: Out of 552 patients with mean age TRANS of 14.8 ± 51.2 years, the male TRANS/ female TRANS ratio was 1.38 to 1. The most common expressive findings in patients were ground-glass opacity (GGO) (87.3%), peripheral distribution (82.4%) and posterior distribution (81.5%). The most conflicting findings in patients were pleural effusion HP pleural effusion MESHD (7.6%), peribronchovascular distribution (7.6%), and lymphadenopathy HP lymphadenopathy MESHD (5.1%). The peripheral distribution (p = 0.034), round opacities (p = 0.02), single lobe (p = 0.003) and pleural effusion HP pleural effusion MESHD (p = 0.037) were significantly in people under and over 50 years of age TRANS.Conclusion: In summary, the present study indicated that in addition to GGO, peripheral distribution findings could be a vital diagnostic choice in COVID-19 patients.

    Coronavirus Disease MESHD 2019 (COVID-19) in Children TRANS: A Systematic Review of Imaging Findings

    Authors: Susan C Shelmerdine; Jovan Lovrenski; Pablo Caro-Domínguez; Seema Toso; Collaborators of the European Society of Paediatric Radiology cardiothoracic imaging taskforce

    doi:10.21203/rs.3.rs-22081/v1 Date: 2020-04-08 Source: ResearchSquare

    Background:Covid-19, a novel coronavirus infection MESHD which can cause a severe respiratory illness MESHD, has been declared a pandemic by the World Health Organisation (WHO). As children TRANS appear less severely affected than adults TRANS, their imaging appearances are not extensively reported.Objectives:To systematically review available literature regarding imaging findings in paediatric cases of Covid-19.Materials and Methods:Four databases (Medline, Embase, Cochrane, Google Scholar) were searched for articles describing imaging findings in children TRANS with Covid-19. All modalities, age <18 years and foreign language articles were included. Descriptive statistics were used to identify pattern, location of imaging findings and association with outcomes.Results:Twenty two articles were included, reporting chest imaging findings in 382 children TRANS, of which 372 (97.4%) underwent CT. Criteria for imaging was lacking. At diagnosis, 120/372 (32.3%) had a normal CT. Abnormalities MESHD were more common in the lower lobes and predominantly unilateral. The most common imaging pattern was ground glass opacification (136/246, 55.3%). None of the studies described lymphadenopathy HP lymphadenopathy MESHD, while pleural effusions HP pleural effusions MESHD (2/246, 0.8%) were rare. Improvement at follow-up CT imaging, (3 – 15 days later) was seen in 27/91 (29.7%), remained normal in 23/91 (25.3%) and progressed in 11/91 (12.1%).Conclusions:CT chest findings in children TRANS with Covid-19 are frequently normal or mild. Lower lobes are predominantly affected by patchy ground glass opacification. Appearances at follow-up remain normal or improve in the majority of children TRANS. Chest CT imaging adds little to the further management of the patient and should be reserved for severe cases or identifying alternative diagnoses.This study was registered in PROSPERO, an international prospective register of systematic reviews (Registration ID: CRD42020175945

    A Systematic Meta-Analysis of CT Features of COVID-19: Lessons from Radiology

    Authors: Vasantha Kumar Venugopal; Vidur Mahajan; Sriram Rajan; Vikash Kumar Agarwal; Ruchika Rajan; Salsabeel Syed; Harsh Mahajan

    doi:10.1101/2020.04.04.20052241 Date: 2020-04-07 Source: medRxiv

    Several studies have been published in the past few months describing the CT features of Coronavirus Disease MESHD 2019 (COVID-19). There is a great degree of heterogeneity in the study designs, lesion descriptors used and conclusions derived. In our systematic analysis and meta-review, we have attempted to homogenize the reported features and provide a comprehensive view of the disease pattern and progression in different clinical stages. After an extensive literature search, we short-listed and reviewed 49 studies including over 4145 patients with 3615 RT-PCR positive cases of COVID-19 disease. We have found that there is a good agreement among these studies that diffuse bilateral ground-glass opacities (GGOs) is the most common finding at all stages of the disease followed by consolidations and mixed density lesions. 78% of patients with RT-PCR confirmed COVID-19 infections had either ground-glass opacities, consolidation or both. Inter-lobular septal thickening was also found to be a common feature in many patients in advanced stages. The progression of these initial patchy ground-glass opacities and consolidations to diffuse lesions with septal thickening, air bronchograms in the advanced stages, to either diffuse white-out lungs needing ICU admissions or finally resolving completely without or with residual fibrotic strips was also found to be congruent among multiple studies. Prominent juxta-lesional pulmonary vessels, pleural effusion HP pleural effusion MESHD and lymphadenopathy HP lymphadenopathy MESHD in RT-PCR proven cases were found to have poor clinical prognosis. Additionally, we noted wide variation in terminology used to describe lesions across studies and suggest the use of standardized lexicons to describe findings related to diseases of vital importance.

    Clinical and Imaging features in COVID-19 Patients: Analysis of Data from Patients in Non-pandemic areas

    Authors: Shengkun Peng; Lingai Pan; Shaojin Zhang; Yalong Liu; Hua Zhang; Liming Tan; Yang Guo; Xiaobo Huang; Jie Zeng; Hong Pu

    doi:10.21203/rs.3.rs-21373/v1 Date: 2020-04-04 Source: ResearchSquare

    Purpose To describe the imaging characteristics in COVID-19 Patients from non-pandemic regions to improve understanding of the disease. Methods We reviewed chest CT scans of 30 COVID-19 patients from three hospitals in Sichuan province, China. Results Typical CT manifestations include the involvement of multiple lobes, mostly in the peripheral zone of the lungs, and subpleural distribution. GGO, crazy paving or mixed GGO and consolidation is the most common signs. Few patients can present small amount of pleural effusion HP pleural effusion MESHD. It is worth noting that none of the lung cavities, tree buds, and lymphadenopathy HP lymphadenopathy MESHD appeared. The follow-up imaging findings of some patients showed progress when the initial CT score reached 7. Conclusion The CT scan still play an important role in screening the COVID-19, most of the images present positive signs, mainly subpleural, multiple GGO. CT might can predict the severity or whether the patient will progress to severe illness. A small number of patients may be missed if they are based on CT findings alone, which should be closely combined with the patient's epidemiological history and nucleic acid test.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).
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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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