Corpus overview


MeSH Disease

Human Phenotype

There are no HP terms in the subcorpus



There are no seroprevalence terms in the subcorpus

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    Driving Force of Covid-19 Among People Living With HIV MESHD/ AIDS MESHD in Wuhan, China

    Authors: Wei Guo; Fangzhao Ming; Yu Dong; Qian Zhang; Lian Liu; Ming Gao; Xiaoxia Zhang; Pingzheng Mo; Yong Feng; Weiming Tang; Ke Liang

    doi:10.21203/ Date: 2020-08-04 Source: ResearchSquare

    Background: Even people living with HIV MESHD/ AIDS MESHD (PLWHA) were considered to be at increased risk of SARS-CoV-2 infection MESHD, the driving force among this group of individuals is still not clear. Methods: We investigated 1,701 PLWHA through a telephone interview and found 11 COVID-19 patients in four districts of Wuhan, China. The demographic features and major clinical characteristics of these patients were retrieved from the information management systems for COVID-19 patients of four districts’ CDC. Statistical analysis was performed to find out the driving force of COVID-19 among PLWHA.Results: The incidence proportion of COVID-19 in PLWHA is 0.6% (95% CI: 0.2% - 1.0%), which is comparable to the overall population incidence rate in Wuhan city (0.6%). Nine out of the 11 COVID-19/ AIDS MESHD patients had relatively high CD4+ T lymphocyte count (>200/μl) and undetectable HIV viral load (<20 copies/ml), and ten of them were on antiretroviral therapy. PLWHA who were old, had low CD4+ T lymphocyte count, infected HIV MESHD through homosexual activity, and had been diagnosed for HIV MESHD for a long time, were more likely to develop COVID-19.Conclusions: PLWHA has comparable COVID-19 morbidity rates as the general population, and older age TRANS, low CD4 count, long length since HIV diagnosis, and treatment-naive were potential driving forces of COVID-19 occurrence among PLWHA. Strategies in preventing SARS-CoV-2 infection MESHD among PLWHA with worse immune responses are needed. Article Summary Line: As COVID-19 continues to spread around the world, people living with HIV MESHD/ AIDS MESHD (PLWHA) are also at risk of infection TRANS risk of infection TRANS with SARS-CoV-2. We investigated the factors associated with SARS-CoV-2 infection MESHD among PLWHA in Wuhan, China.

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MeSH Disease
Human Phenotype

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