Corpus overview


Overview

MeSH Disease

Human Phenotype

There are no HP terms in the subcorpus


Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

    displaying 1 - 1 records in total 1
    records per page




    Driving Force of Covid-19 Among People Living With HIV MESHD/ AIDS MESHD in Wuhan, China

    Authors: Wei Guo; Fangzhao Ming; Yu Dong; Qian Zhang; Lian Liu; Ming Gao; Xiaoxia Zhang; Pingzheng Mo; Yong Feng; Weiming Tang; Ke Liang

    doi:10.21203/rs.3.rs-53351/v1 Date: 2020-08-04 Source: ResearchSquare

    Background: Even people living with HIV MESHD/ AIDS MESHD (PLWHA) were considered to be at increased risk of SARS-CoV-2 infection MESHD, the driving force among this group of individuals is still not clear. Methods: We investigated 1,701 PLWHA through a telephone interview and found 11 COVID-19 patients in four districts of Wuhan, China. The demographic features and major clinical characteristics of these patients were retrieved from the information management systems for COVID-19 patients of four districts’ CDC. Statistical analysis was performed to find out the driving force of COVID-19 among PLWHA.Results: The incidence proportion of COVID-19 in PLWHA is 0.6% (95% CI: 0.2% - 1.0%), which is comparable to the overall population incidence rate in Wuhan city (0.6%). Nine out of the 11 COVID-19/ AIDS MESHD patients had relatively high CD4+ T lymphocyte count (>200/μl) and undetectable HIV viral load (<20 copies/ml), and ten of them were on antiretroviral therapy. PLWHA who were old, had low CD4+ T lymphocyte count, infected HIV MESHD through homosexual activity, and had been diagnosed for HIV MESHD for a long time, were more likely to develop COVID-19.Conclusions: PLWHA has comparable COVID-19 morbidity rates as the general population, and older age TRANS, low CD4 count, long length since HIV diagnosis, and treatment-naive were potential driving forces of COVID-19 occurrence among PLWHA. Strategies in preventing SARS-CoV-2 infection MESHD among PLWHA with worse immune responses are needed. Article Summary Line: As COVID-19 continues to spread around the world, people living with HIV MESHD/ AIDS MESHD (PLWHA) are also at risk of infection TRANS risk of infection TRANS with SARS-CoV-2. We investigated the factors associated with SARS-CoV-2 infection MESHD among PLWHA in Wuhan, China.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).
The web page can also be accessed via API.

Sources


Annotations

All
None
MeSH Disease
Human Phenotype
Transmission
Seroprevalence


Export subcorpus as...

This service is developed in the project nfdi4health task force covid-19 which is a part of nfdi4health.

nfdi4health is one of the funded consortia of the National Research Data Infrastructure programme of the DFG.