Corpus overview


Overview

MeSH Disease

Human Phenotype

Pain (2)

Falls (1)


Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Comparison of Acute Appendicitis MESHD Before and Within COVID 19 Era: A Retrospective Study from Rural Nepal

    Authors: Suman Baral; Rajkumar Chhetri; Neeraj Thapa

    doi:10.21203/rs.3.rs-47510/v1 Date: 2020-07-22 Source: ResearchSquare

    Background Currently, the world has been engulfed with the pandemicity of the novel severe acute respiratory syndrome coronavirus 2 MESHD (SARS-CoV-2) and various mitigating measures like lock down and social distancing are being taken which have created significant impact in the emergency surgical health delivery including acute appendicitis MESHD ( AA MESHD). The main aim of this study was to compare the demographic and clinical parameters between two cohorts before the onset of lockdown and within the pandemic.Methods A retrospective cohort analysis was performed between two groups of patients presenting with AA MESHD in one of the tertiary care centers of rural Nepal. The cohorts were named group A and group B who presented three months prior to and after initiation of lockdown on March 24 2020 respectively. These two groups of patients were compared in demographics, clinicopathological characteristics and surgical aspects of acute appendicitis MESHD. Results There were 42 patients in group A and 50 patients in group B. Mean age TRANS of the patients was 31.32±171.18 years with male TRANS preponderance in group B (N= 29). Mean duration of pain HP increased significantly in group B [55.4±25.9(B) vs 43.52±30.3(A) hours, P= 0.04] along with mean duration of surgery. [51.06±9.4(B) vs 45.27±11.8(A) minutes, P= 0.015] There was significant decrease in post-operative hospital stay among group B patients. [3.05±1.19(B) vs 4.05±0.8(A) days, P= 0.0001] Complicated cases increased in group B (38% vs 33.3 % including appendicular perforation in 10 cases with perforation rate of 20 %. Six of these 10 cohorts had fecalith present intraoperatively. (P= 0.0001) Similarly, mean duration of presentation to hospital significantly increased in group B patients with perforation. [64.8±22.7(B) vs 52.05±14.7(A) hours]    Conclusion During the adversity of COVID 19, increased number of cases of AA can be dealt with surgery as the chances of late presentation and complexity of the lesion exists.

    Comparison of Acute Appendicitis MESHD Before and Within COVID 19 Era: A Retrospective Study from Rural Nepal

    Authors: Suman Baral; Rajkumar Chhetri; Neeraj Thapa

    doi:10.21203/rs.3.rs-47510/v2 Date: 2020-07-22 Source: ResearchSquare

    Background Currently, the world has been engulfed with the pandemicity of the novel severe acute respiratory syndrome coronavirus 2 MESHD (SARS-CoV-2) and various mitigating measures like lock down and social distancing are being taken which have created significant impact in the emergency surgical health delivery including acute appendicitis MESHD ( AA MESHD). The main aim of this study was to compare the demographic and clinical parameters between two cohorts before the onset of lockdown and within the pandemic.Methods A retrospective cohort analysis was performed between two groups of patients presenting with AA MESHD in one of the tertiary care centers of rural Nepal. The cohorts were named group A and group B who presented three months prior to and after initiation of lockdown on March 24 2020 respectively. These two groups of patients were compared in demographics, clinicopathological characteristics and surgical aspects of acute appendicitis MESHD. Results There were 42 patients in group A and 50 patients in group B. Mean age TRANS of the patients was 31.32±171.18 years with male TRANS preponderance in group B (N= 29). Mean duration of pain HP increased significantly in group B [55.4±25.9(B) vs 43.52±30.3(A) hours, P= 0.04] along with mean duration of surgery. [51.06±9.4(B) vs 45.27±11.8(A) minutes, P= 0.015] There was significant decrease in post-operative hospital stay among group B patients. [3.05±1.19(B) vs 4.05±0.8(A) days, P= 0.0001] Complicated cases increased in group B (38% vs 33.3 % including appendicular perforation in 10 cases with perforation rate of 20 %. Six of these 10 cohorts had fecalith present intraoperatively. (P= 0.0001) Similarly, mean duration of presentation to hospital significantly increased in group B patients with perforation. [64.8±22.7(B) vs 52.05±14.7(A) hours]    Conclusion During the adversity of COVID 19, increased number of cases of AA can be dealt with surgery as the chances of late presentation and complexity of the lesion exists.

    Changes in Emergency Department attendances before and after COVID-19 lockdown implementation: a cross sectional study of one urban NHS Hospital Trust

    Authors: Kate Honeyford; Charles Coughlan; Paul Expert; Gabriel Burcea; Ian Maconochie; Anne Kinderlerer; Graham S Cooke; Ceire S Costelloe

    doi:10.1101/2020.07.20.20157560 Date: 2020-07-21 Source: medRxiv

    Background Emergency Department (ED) attendances have fallen HP across the UK since the "lockdown" introduced on 23rd March 2020 to limit the spread of coronavirus disease MESHD 2019 (COVID-19). We hypothesised that reductions would vary by patient age TRANS and disease type. We examined pre- and in-lockdown ED attendances for two COVID-19 unrelated diagnoses; one likely to be affected by lockdown measures ( gastroenteritis MESHD) and one likely to be unaffected ( appendicitis MESHD). Methods Retrospective cross-sectional study conducted across two EDs in one London hospital Trust. We compared all adult TRANS and paediatric ED attendances, before (January 2020) and during lockdown (March/April 2020). Key patient demographics, method of arrival and discharge location were compared. We used SNOMED codes to define attendances for gastroenteritis and appendicitis MESHD. Results ED attendances fell HP from 1129 per day before lockdown to 584 in-lockdown; 51.7% of pre-lockdown rates. In-lockdown attendances were lowest for under-18s (16.0% of pre-lockdown). The proportion of patients admitted to hospital increased from 17.3% to 24.0% and the proportion admitted to intensive care increased four-fold. Attendances for gastroenteritis MESHD fell HP from 511 to 103; 20.2% of pre-lockdown rates. Attendances for appendicitis MESHD also decreased, from 144 to 41; 28.5% of pre-lockdown rates. Conclusion ED attendances fell HP substantially following lockdown implementation. The biggest reduction was for under-18s. We observed reductions in attendances for gastroenteritis and appendicitis MESHD. This may reflect lower rates of infectious disease MESHD transmission TRANS, though the fall HP in appendicitis MESHD-related attendances suggests that behavioural factors are also important. Larger studies are urgently needed to understand changing patterns of ED use and access to emergency care during the COVID-19 pandemic.

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MeSH Disease
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Transmission
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