Corpus overview


Overview

MeSH Disease

Human Phenotype

Fever (1)

Diarrhea (1)

Vomiting (1)

Cough (1)

Dyspnea (1)


Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Clinical characteristics of neonates with coronavirus disease MESHD 2019 (COVID-19): a systematic review

    Authors: Yuan Hu; Jing Xiong; Yuan Shi

    doi:10.21203/rs.3.rs-50795/v1 Date: 2020-07-29 Source: ResearchSquare

    This study aimed to summarize the existing literature on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection MESHD in newborns to clarify the clinical features and outcomes of neonates with COVID-19. A systematic search was performed in PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data, and VIP databases from January 1, 2019 to April 30, 2020. The references of relevant studies were also searched. A descriptive summary was organized by aspects of clinical presentations (symptoms, laboratory examinations, and imaging) and outcomes. We identified 14 studies reporting 18 newborns with COVID-19. The most common clinical manifestations were fever HP fever MESHD (62.5%), shortness of breath MESHD (50.0%), diarrhea HP diarrhea MESHD/ vomiting HP vomiting MESHD/feeding intolerance(43.8%), cough HP (37.5%), dyspnea HP dyspnea MESHD (25.0%), and nasal congestion/runny nose/ sneeze HP(25.0%). Atypical symptoms included jaundice HP jaundice MESHD and convulsion MESHD. Lymphocyte numbers decreased in 5 cases, and radiographic findings were likely to show pneumonia HP pneumonia MESHD. All newborns recovered and discharged from the hospital, and there was no death.Conclusion: Clinical symptoms of neonatal SARS-CoV-2 infection MESHD are atypical, most of them are mild. Up to now, the prognosis of newborns is good, and there is no death. Intrauterine vertical transmission TRANS is possible, but confirmed evidence is still lacking. The Long-term follow-up of potential influences of SARS-CoV-2 infection MESHD on neonates need further exploration.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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