Corpus overview


Overview

MeSH Disease

Human Phenotype

Fever (2)

Cough (2)

Visual loss (1)

Retinitis (1)

Pneumonia (1)


Transmission

Seroprevalence
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    Varicella Zoster Virus MESHD Induced Acute Retinal Necrosis MESHD Following Acute Meningoencephalitis MESHD in a Patient with Presumed COVID-19

    Authors: Kiana Hassanpour; Faezeh Khorasanizadeh; Hamid Ahmadieh; Mahmood Nabavi; Narsis Daftarian; Alireza Ramezani

    doi:10.21203/rs.3.rs-54356/v1 Date: 2020-08-05 Source: ResearchSquare

    Background: To report the coincidence of acute retinal necrosis syndrome MESHD ( ARN MESHD) following acute meningoencephalitis MESHD and presumed coronavirus disease MESHD 2019 (COVID-19) in an immunocompetent patient. Case presentation: A 58-year old female TRANS presented to our emergency department complaining of sudden unilateral visual loss MESHD visual loss HP following a recent hospitalization for a viral meningoencephalitis MESHD. Magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) analysis, polymerase chain reaction (PCR) of the aqueous humor, reverse transcriptase polymerase chain reaction (RT-PCR) of the nasopharyngeal swab specimen, chest computed tomography (CT), and fundus photography were performed for the patient. Ophthalmic examination revealed severe ocular inflammation MESHD and yellowish patches of necrotizing retinitis MESHD retinitis HP in the right eye compatible with the diagnosis of ARN MESHD. The result of PCR on the aqueous humor was positive for VZV. The patient received one intravitreal ganciclovir injection and 10 days intravenous ganciclovir followed by oral acyclovir. The patient underwent COVID-19 screening tests; chest CT-scan showed the features highly suggestive for COVID-19 while the RT-PCR was negative two times. Two months later, BCVA reached 20/70 in the right eye. The anterior chamber reaction and KPs resolved and the vitreous haziness significantly decreased Conclusion: A case of VZV induced ARN MESHD following acute meningoencephalitis MESHD was observed in association with presumed COVID-19. This could be an incidental finding in the pandemic era of COVID-19; however, it could also suggest that COVID-19 might trigger ARN MESHD in cases having latent herpes family viruses. 

    Neurological Involvement of Coronavirus Disease MESHD 2019: A Systematic Review

    Authors: Malik Ghannam; Qasem Alshaer; Mustafa Al-Chalabi; Lara Zakarna; Jetter Robertson; Georgios Manousakis

    doi:10.21203/rs.3.rs-31183/v1 Date: 2020-05-23 Source: ResearchSquare

    Background: In December 2019, unexplained cases of pneumonia HP pneumonia MESHD emerged in Wuhan, China, which were found to be secondary to the novel coronavirus SARS-CoV-2. On March 11, 2020, the WHO declared the Coronavirus Disease MESHD 2019 (COVID-2019) outbreak, a pandemic. Although the most common presentations of COVID-19 are fever HP fever MESHD, cough HP cough MESHD and shortness of breath MESHD, several clinical observations indicate that COVID-19 does affect the central and peripheral nervous system.  Methods: We conducted a systematic literature search from December 01, 2019 to May 14, 2020 using multiple combinations of keywords from PubMed and Ovid Medline databases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We included articles with cases of COVID-19 that were evident for neurological involvement.  Results: We were able to identify 82 cases of COVID-19 with neurological complications. The mean age TRANS was 62.28 years. 37.8% of the patients were women (n = 31). 48.8% of the patients (n=40) had cerebrovascular insults, 28% (n=23) had neuromuscular disorders MESHD, 18.3% of the patients (n=15) had encephalitis HP encephalitis MESHD or encephalopathy HP encephalopathy MESHD, and 2.4% (n=2) presented with status epilepticus HP status epilepticus MESHD. Conclusions: Neurological manifestations of COVID-19 infection MESHD are not rare, especially large vessel stroke HP stroke MESHD, Guillain barre syndrome MESHD and meningoencephalitis MESHD. Moving forward, further studies are needed to clarify the prevalence SERO of the neurological complications of COVID-19, investigate their biological backgrounds, and test treatment options. Physicians should be cautious not to overlook other neurological diagnoses that can mimic COVID-19 during the pandemic.

    Hemisensory paresthesia HP as the initial symptom of a SARS-Coronavirus-2 infection MESHD. A Case report.

    Authors: Myriam Herrnberger; Nadine Durmazel; Frank Birklein

    doi:10.21203/rs.3.rs-26305/v1 Date: 2020-04-30 Source: ResearchSquare

    Neurological symptoms MESHD might be associated with a Covid-19 infection MESHD. There are frequent reports in the last weeks. The neurological symptoms range from harmless side effects of a viral infection to meningoencephalitis MESHD and acute haemorrhagic necrotizing encephalopathy MESHD necrotizing encephalopathy HP.Our patient reported burning headache HP headache MESHD and paresthesia HP as the initial symptoms mainly without other signs of viral infection like cough or fever MESHD cough HP or fever HP. Such an initial neurological presentation seems to be rare. Most cases have neurological symptoms MESHD which can be expected after severe systemic viral infections MESHD like fever HP fever MESHD associated headache HP headache MESHD. Many COVID-19 patients with mild disease are at home and the further course is unknown. Our case shows, that neurological symptoms can be the first manifestation of an COVID-19 disease. While restricted paraesthesia has been reported in SARS-CoV-2 infections MESHD, hemisymptoms have not been described as initial symptoms. 

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).
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MeSH Disease
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