Corpus overview


MeSH Disease

Human Phenotype

Paralysis (1)


There are no transmission terms in the subcorpus


There are no seroprevalence terms in the subcorpus

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    Early Guillain-Barré syndrome in COronaVIrus Disease MESHD 2019 (COVID-19): a case report from an Italian COVID-Hospital

    Authors: Donatella Ottaviani; Federica Boso; Enzo Tranquillini; Ilaria Gapeni; Giovanni Pedrotti; Susanna Cozzio; Giovanni M. Guarrera; Bruno Giometto

    doi:10.21203/ Date: 2020-04-24 Source: ResearchSquare

    Guillain Barré syndrome ( GBS MESHD) is an acute polyradiculoneuropathy MESHD associated with dysimmune processes, often related to a previous infectious exposure. During Italian Severe Acute Respiratory Syndrome Coronavirus-2 MESHD outbreak, a woman presented with a rapidly progressive flaccid paralysis MESHD paralysis HP with unilateral facial neuropathy MESHD after a few days of mild respiratory symptoms. Coronavirus was detected by nasopharyngeal swab, but there was no evidence of its presence in her cerebrospinal fluid, which confirmed the typical albumin-cytological dissociation of GBS MESHD, along with consistent neurophysiological data. Despite immunoglobulin infusions and intensive supportive care, her clinical picture worsened simultaneously both from respiratory and neurological point of view, as if reflecting different aspects of the same systemic inflammatory response. Similar early complications have already been observed in patients with para-infectious GBS MESHD related to Zika virus, but pathological mechanisms have yet to be established.

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MeSH Disease
Human Phenotype

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