Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence
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    Does Endometriosis HP Increase Susceptibility to COVID–19 Infections? A case-control study in Women of Reproductive Age TRANS

    Authors: Bahram Moazzami; Shahla Chaichian; Saeed Samie; Masoumeh Majidi Zolbin; Fatemeh Jesmi; Meisam Akhlaghdoust; Mahin Ahmadi Pishkuhi; Zahra Sadat Mirshafiei; Fereshteh Khalilzadeh; Dorsa Safari

    doi:10.21203/rs.3.rs-45026/v1 Date: 2020-07-17 Source: ResearchSquare

    Background: In today’s world, coronavirus disease MESHD 2019 (COVID–19) is the most critical health problem and research is continued on studying the associated factors. But it is not clear whether endometriosis HP endometriosis MESHD increases the risk of COVID–19.Methods: Women who referred to the gynecology clinic were evaluated and 507 women with endometriosis HP endometriosis MESHD (case group) were compared with 520 women without endometriosis HP endometriosis MESHD (control group). COVID–19 infection MESHD, symptoms, exposure, hospitalization, isolation, H1N1 infection MESHD and vaccination, and past medical history of the participants were recorded and compared between the groups using IBM SPSS Statistics for Windows version 21.Results: Comparison between the groups represent COVID–19 infection MESHD in 3.2% of the case group and 3% of the control group (P=.942). The control group had a higher frequency of asymptomatic TRANS asymptomatic MESHD infection (95.7% vs. 94.5%; P<.001) and fever HP fever MESHD (1.6% vs. 0%; P=.004), while the frequency of rare symptoms was more common in the case group (P<.001). The average disease period was 14 days in both groups (P=.694). COVID–19 infection MESHD was correlated with close contact TRANS (r=.331; P<.001 in the case group and r=.244; P<.001 in the control group), but not with the history of thyroid disorders MESHD, H1N1 vaccination, traveling TRANS to high-risk areas, and social isolation (P>.05).Conclusion: Endometriosis HP does not increase the susceptibility to COVID–19 infections, but alters the manifestation of the disease. The prevalence SERO of the disease may depend on the interaction between the virus and the individual’s immune system but further studies are required in this regard. 

    Clinical characteristics of 134 convalescent patients with COVID-19 in Guizhou, China

    Authors: Siqin Zhang; Lin Liu; Bin Yang; Rou Li; Jianhua Luo; Jing Huang; Yanjun Long; Ying Huang; Jianping Zhou; Yan Zha; Xiangyan Zhang

    doi:10.21203/rs.3.rs-41986/v1 Date: 2020-07-13 Source: ResearchSquare

    Background: Previous studies have focused on the clinical characteristics of hospitalized patients with the novel 2019 coronavirus disease MESHD (COVID-19). Limited data are available for convalescent patients. This study aimed to evaluate the clinical characteristics of discharged COVID-19 patients.Methods: In this retrospective study, we extracted data for 134 convalescent patients with COVID-19 in Guizhou Provincial Staff Hospital from February 15 to March 31, 2020. Cases were analyzed on the basis of demographic, clinical, and laboratory data as well as radiological features. Results: Of 134 convalescent patients with COVID-19, 19 (14.2%) were severe cases, while 115 (85.8%) were non-severe cases. The median patient age TRANS was 33 years (IQR, 21.8 to 46.3), and the cohort included 69 men and 65 women. Compared with non-severe cases, severe patients were older and had more chronic comorbidities, especially hypertension HP hypertension MESHD, diabetes MESHD, and thyroid disease MESHD (P<0.05). Leukopenia HP Leukopenia MESHD was present in 32.1% of the convalescent patients and lymphocytopenia MESHD was present in 6.7%, both of which were more common in severe patients. 48 (35.8%) of discharged patients had elevated levels of alanine aminotransferase, which was more common in adults TRANS than in children TRANS (40.2% vs 13.6%, P=0.018). A normal chest CT was found in 61 (45.5%) patients during rehabilitation. Severe patients had more ground-glass opacity, bilateral patchy shadowing, and fibrosis MESHD. No significant differences were observed in the positive rate of IgG and/or IgM antibodies SERO between severe and non-severe patients.Conclusion: Leukopenia HP Leukopenia MESHD, lymphopenia HP lymphopenia MESHD, ground-glass opacity, and fibrosis MESHD are common in discharged severe COVID-19 patients, and liver injury MESHD is common in discharged adult TRANS patients. We suggest physicians develop follow-up treatment plans based on the different clinical characteristics of convalescent patients. 

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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