Corpus overview


MeSH Disease

Human Phenotype

Fever (1)

Cough (1)

Fatigue (1)

Headache (1)


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    ENT Manifestations in COVID-19 Positive Patients

    Authors: Dr. Vaibhav Kuchhal; Dr. Shahzad Ahmad; Dr. Priyanka Chaurasia; Dr. Pradeep Rawat

    doi:10.21203/ Date: 2020-10-09 Source: ResearchSquare

    AIM: To study the status of ear, nose and throat in the patients diagnosed with the CoViD-19.MATERIAL AND METHODS: This is a perspective study in patients admitted in the isolation wards of Dr. Sushila Tiwari Hospital Haldwani between March 2020 and July 2020. There were 465 symptomatic patients out of total 727 patients diagnosed with CoViD-19 .RESULT: Since the CoViD-19 pandemic has begun, many individuals have noted many ENT manifestations along with the other general symptoms like fever HP fever MESHD(395 pt)> cough HP (326 pt) > weakness/fatigue MESHD fatigue HP (190 pt ) >difficulty in breathing (89 pt ) > muscle ache MESHD (58 pt ) > headache HP headache MESHD (56 pt) & diarrhoea MESHD (24 pt). Among ENT manifestations throat symptoms were found most common including loss of taste in 74 pt. It was noticed that most commonly sweet and salt goes first then sour taste vanish and bitter and chilli taste goes in the end, most of them were reversible after 2-3 weeks. Among nasal symptoms nasal congestion was found most common (72 pt) followed by loss of smell (88 pt), nasal blockage (66 pt) & runny nose (47 pt). loss of smell was also reversible in most of the cases after 2-3 weeks. Ear symptoms were not so commonly found. Although itching in bilateral ear, sensation of ear fullness, ear ache MESHD and conductive hearing loss MESHD were complained by some patients.CONCLUSION: This study represents the initial findings of all individuals with ENT manifestations along with the chemosensory loss in the symptomatic confirmed covid-19 patients. During the ongoing COVID-19 pandemic, changes in smell or taste are not being considered indicative of possible COVID-19 infection MESHD—especially in the absence of other high-suspicion symptoms.

    Regional Association of Disability and SARS-CoV-2 Infection MESHD in 369 Counties of the United States

    Authors: Oluwaseyi Olulana; Vida Abedi; Venkatesh Avula; Durgesh Chaudhary; Ayesha Khan; Shima Shahjouei; Jiang Li; Ramin Zand

    doi:10.1101/2020.06.24.20139212 Date: 2020-06-26 Source: medRxiv

    Background: There have been outbreaks of SARS-CoV-2 in long term care facilities and recent reports of disproportionate death rates among the vulnerable population. The goal of this study was to better understand the impact of SARS-CoV-2 infection MESHD on the non-institutionalized disabled population in the United States using data from the most affected states as of April 9th, 2020. Methods: This was an ecological study of county-level factors associated with the infection MESHD and mortality rate of SARS-CoV-2 in the non-institutionalized disabled population. We analyzed data from 369 counties from the most affected states (Michigan, New York, New Jersey, Pennsylvania, California MESHD, Louisiana, Massachusetts) in the United States using data available by April 9th, 2020. The variables include changes in mobility reported by Google, race/ethnicity, median income, education level, health insurance, and disability information from the United States Census Bureau. Bivariate regression analysis adjusted for state and median income was used to analyze the association between death rate and infection rate. Results: The independent sample t-test of two groups (group 1: Death rate[≥] 3.4% [median] and group 2: Death rate < 3.4%) indicates that counties with a higher total population, a lower percentage of Black males TRANS and females TRANS, higher median income, higher education, and lower percentage of disabled population have a lower rate (< 3.4%) of SARS-CoV-2 related mortality (all p-values<4.3E-02). The results of the bivariate regression when controlled for median income and state show counties with a higher White disabled population (est: 0.19, 95% CI: 0.01-0.37; p-value:3.7E-02), and higher population with independent living difficulty (est: 0.15, 95% CI: -0.01-0.30; p-value: 6.0E-02) have a higher rate of SARS-CoV-2 related mortality. Also, the regression analysis indicates that counties with higher White disabled population (est: -0.22, 95% CI: -0.43-(-0.02); p-value: 3.3E-02), higher population with hearing disability MESHD (est: -0.26, 95% CI: -0.42- (-0.11); p-value:1.2E-03), and higher population with disability in the 18-34 years age group TRANS (est: -0.25, 95% CI: -0.41-(-0.09); p-value:2.4E-03) show a lower rate of SARS-CoV-2 infection MESHD. Conclusion: Our results indicate that while counties with a higher percentage of non-institutionalized disabled population, especially White disabled population, show a lower infection rate, they have a higher rate of SARS-CoV-2 related mortality. Keywords: Disability disparities, Healthcare disparities, Non-institutionalized disabled population, Racial disparity, Health disparity, Socioeconomic factors, COVID19, United States, Population-based analysis, Ecological study.

    Utility and limitations of Google searches on sensory loss as markers for new COVID-19 cases

    Authors: Kim Asseo; Fabrizio Fierro; Yuli Slavutsky; Johannes Frasnelli; Masha Y Niv

    doi:10.1101/2020.05.07.20093955 Date: 2020-05-11 Source: medRxiv

    Web tools are widely used among population to obtain health related information, and these data are often employed for public health monitoring. Here we analyzed searches related to smell loss and taste loss MESHD, recently linked to COVID-19, as well as sight loss and hearing loss MESHD, not included in the COVID-19 symptoms list. Google Trends results per region (Italy) or state (United States) over several weeks were compared to the number of new cases prevalence SERO in that geographical area. Taste and smell loss searches were correlated with each other, and, during a limited time window, with new COVID-19 cases. However, this correlation decreased with time, attributable, at least in part, to media coverage. As new symptoms are being discovered for COVID-19 and the pandemic continues to spread around the globe, the lesson learned here, that correlation between public interest in novel symptoms of infectious disease MESHD has an initial spike (the ''surprise rise'') and subsequently goes to a new baseline due to ''knowledge saturation'', is of general and practical value for the public.

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MeSH Disease
Human Phenotype

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