Corpus overview


MeSH Disease

Human Phenotype

Anxiety (140)

Insomnia (7)

Pain (7)

Sleep disturbance (6)

Fever (6)


    displaying 11 - 20 records in total 140
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    Prevalence SERO and risk factors of disability and anxiety HP anxiety MESHD in a retrospective cohort of 432 survivors of Coronavirus Disease-2019 (Covid-19) from China

    Authors: Siyi Zhu; Qiang Gao; Lin Yang; Yonghong Yang; Wenguang Xia; Xiguo Cai; Yanping Hui; Di Zhu; Yanyan Zhang; Guiqing Zhang; Shuang Wu; Yiliang Wang; Zhiqiang Zhou; Hongfei Liu; Changjie Zhang; Bo Zhang; Jianrong Yang; Mei Feng; Zhong Ni; Baoyu Chen; Chunping Du; Hongchen He; Yun Qu; Quan Wei; Chengqi He; Jan D. Reinhardt

    doi:10.1101/2020.08.26.20182246 Date: 2020-09-01 Source: medRxiv

    Objective: To estimate the prevalence SERO of disability and anxiety HP anxiety MESHD in Covid-19 survivors at discharge from hospital and analyze relative risk by exposures. Design: Multi-center retrospective cohort study. Setting: Twenty-eight hospitals located in eight provinces of China. Methods: A total of 432 survivors with laboratory-confirmed SARS CoV-2 infection participated MESHD in this study. At discharge, we assessed instrumental activities of daily living (IADL) with Lawton's IADL scale, dependence in activities of daily living (ADL) with the Barthel Index, and anxiety HP anxiety MESHD with Zung's self-reported anxiety HP anxiety MESHD scale. Exposures included comorbidity, smoking, setting (Hubei vs. others), disease severity, symptoms, and length of hospital stay. Other risk factors considered were age TRANS, gender TRANS, and ethnicity (Han vs. Tibetan). Results: Prevalence SERO of at least one IADL problem was 36.81% (95% CI: 32.39-41.46). ADL dependence was present in 16.44% (95% CI: 13.23-20.23) and 28.70% (95% CI: 24.63- 33.15) were screened positive for clinical anxiety MESHD anxiety HP. Adjusted risk ratio (RR) of IADL limitations (RR 2.48, 95% CI: 1.80-3.40), ADL dependence (RR 2.07, 95% CI 1.15-3.76), and probable clinical anxiety HP anxiety MESHD (RR 2.53, 95% CI 1.69-3.79) were consistently elevated in survivors with severe Covid-19. Age TRANS was an additional independent risk factor for IADL limitations and ADL dependence; and setting (Hubei) for IADL limitations and anxiety HP anxiety MESHD. Tibetan ethnicity was a protective factor for anxiety HP anxiety MESHD but a risk factor for IADL limitations. Conclusion: A significant proportion of Covid-19 survivors had disability and anxiety HP anxiety MESHD at discharge from hospital. Health systems need to be prepared for an additional burden resulting from rehabilitation needs of Covid-19 survivors.

    Predictors of healthcare worker burnout during the COVID-19 pandemic

    Authors: Amy V Ferry; Ryan Wereski; Fiona E Strachan; Nicholas L Mills; Ben Warne; Luke Meredith; Myra Hosmillo; Aminu Jahun; Martin Curran; Surendra Parmar; Laura Caller; Sarah Caddy; Fahad Khokhar; Anna Yakovleva; Grant Hall; Theresa Feltwell; Malte Pinckert; Iliana Georgana; Yasmin Chaudhry; Nicholas Brown; Sonia Goncalves; Roberto Amato; Ewan Harrison; Mathew Beale; Michael Spencer Chapman; David Jackson; Ian Johnston; Alex Alderton; John Sillitoe; Cordelia Langford; Gordon Dougan; Sharon Peacock; Dominic Kwiatowski; Ian Goodfellow; M. Estee Torok; - COVID-19 Genomics Consortium UK

    doi:10.1101/2020.08.26.20182378 Date: 2020-09-01 Source: medRxiv

    Objective We aim to provide a snapshot of the levels of burnout, anxiety HP anxiety MESHD, depression MESHD and distress among healthcare workers during the COVID-19 pandemic. Design, setting, participants We distributed an online survey via social media in June 2020 that was open to any healthcare worker. The primary outcome measure was symptoms of burnout as measured using the Copenhagen Burnout Inventory (CBI). Secondary outcomes of depression MESHD, anxiety HP anxiety MESHD and distress as measured using the Patient Health Questionnaire-9, General Anxiety HP Anxiety MESHD Scale-7, and Impact of Events Scale-Revised were recorded along with subjective measures of stress. Multivariate logistic regression analysis was performed to identify factors associated with burnout, depression MESHD, anxiety HP anxiety MESHD and distress. Results Of 539 persons responding to the survey, 90% were female TRANS, and 26% were aged TRANS 41-50 years, 53% were nurses. Participants with moderate-to-severe burnout were younger (49% [206/424] versus 33% [38/115] under 40 years, P=0.004), and more likely to have pre-existing comorbidities (21% versus 12%, P=0.031). They were twice as likely to have been redeployed from their usual role (22% versus 11%; adjusted odds ratio [OR] 2.2, 95% confidence interval [CI] 1.5-3.3, P=0.042), or to work in an area dedicated to COVID-19 patients (50% versus 32%, adjusted OR 1.6, 95% CI 1.4-1.8, P<0.001), and were almost 4-times more likely to have previous depression MESHD (24% versus 7%; adjusted OR 3.6, 95% CI 2.2-5.9, P=0.012). A supportive workplace team and male TRANS sex protected against burnout reducing the odds by 40% (adjusted OR 0.6, 95% CI 0.5-0.7, P<0.001) and 70% (adjusted OR 0.3, 95% CI 0.2-0.5, P=0.003), respectively. Conclusion Independent predictors of burnout were younger staff, redeployment to a new working area, working with patients with confirmed COVID-19 infection MESHD, and being female TRANS or having a previous history of depression MESHD. Evaluation of existing psychological support interventions is required with targeted approaches to ensure support is available to those most at risk.

    COVID-19 Related Mental Health Burdens: Impact of Educational Level and Relationship Status Among Low Income Earners of Western Uganda

    Authors: Ann Monima Lemuel; Ibe Michael Usman; Kenneth Iceland Kasozi; Eric Osamudiamwen Aigbogun, Jr; Victor Archibong Bassey; Josiah Ifie; Robinson Ssebuufu; Adam Moyosore Afodun; Swase Dominic Terkimbi; Ngala Elvis Mbiydzenyuy; Azeez Adeoye; Joshua Ojodale Aruwa; Odoma Saidi; Fred Ssempijja; John Tabakwot Ayuba; Hope Onohuean; Stellamaris Kembabazi; Theophilus Pius; Viola Nankya; Kevin Matama; Rachael Henry; Helen Yusuf; Susan Christina Welburn

    doi:10.21203/ Date: 2020-09-01 Source: ResearchSquare

    Background: The imposed COVID-19 lockdown is taking a toll mental health, with low-income earners considered particularly affected. The study aimed to investigate level of education and relationship status on awareness of mental healthcare and explore how these factors influence mental health among low income earners in Western Uganda.Methods: A cross sectional descriptive study was undertaken among low-income earners in South Western Uganda. Data were collected from two hundred and fifty-three (253) participants using a structured closed ended questionnaire. Anxiety HP Anxiety MESHD, anger and depression MESHD were assessed using a modified generalized anxiety HP anxiety MESHD disorder (GAD-7), Spielberger’s State-Trait Anger Expression Inventory-2 (STAXI-2) and Beck Depression MESHD Inventory (BDI) item tools respectively.Result: Most respondents were single male TRANS individuals with secondary level. Respondents with tertiary level of education and those with partners had higher score (71.7% and 70.28% respectively) for awareness on mental healthcare. Respondents with primary education level and individuals that were single had higher score (46.98% and 43.72% respectively) for anxiety HP anxiety MESHD. Respondents with primary education level and those living with partners had higher mean score (56.44% and 56.21% respectively) for anger. Respondents with no formal education and those who had lost partners had higher mean score (32.11% and 30.50% respectively) for depression MESHD. Individuals without formal educational and primary education were observed to have a negative correlation (r2 = 47.4 and 6.4% respectively) with awareness on mental healthcare, and the no formal group had positive correlation with anger and depression MESHD (r2 =1.9 and 0.3% respectively), while other groups were negatively correlated (r2 =10.1%). The group of single individuals had a negative correlation with awareness on mental healthcare, anger and depression MESHD (r2 =1.9, 0.8 and 0.3% respectively), and a positive correlation with anxiety HP anxiety MESHD (r2 =3.9%).Conclusion: It is evident that education and relationship status influence awareness on mental healthcare and mental health state among low income earners in Western Uganda. Therefore, we advocate for new approaches in mental healthcare awareness programs equipped with robust strategy, which will focus on improving optimal mental health among these set of people.

    The impact of the COVID-19 pandemic on mental health in the general population: a comparison between Germany and the UK

    Authors: Franziska Knolle; Lisa Ronan; Graham K Murray; Marie-Anne Vanderhasselt; Rudi De Raedt; Eva Van den Bussche; Rajesh Jain; Sachee Tainwala Agrawal; Sandeep Juneja; Sofia Imad; Ullas Kolthur-Seetharam; Hongjie Yu; Lars I Eriksson; Anna Norrby-Teglund; Hans-Gustaf Ljunggren; Niklas K Bjorkstrom; Soo Aleman; Marcus Buggert; Jonas Klingstrom; Kristoffer Stralin; Johan K. Sandberg

    doi:10.1101/2020.08.27.20182980 Date: 2020-09-01 Source: medRxiv

    In March 2020 the SARS-CoV-2infection (COVID-19) was declared a pandemic. In response to its world-wide outbreak radical measures were taken by governments across the world including curfew, quarantine, travel TRANS bans, social distancing, work place and school closures, etc, to reduce the transmission TRANS of the virus. These measures led to dramatic social and economic changes for the general population, in addition to the fears and worries related to the disease and its contraction. First studies report the impact of the pandemic on mental well-being of the general population showing increased levels of anxiety HP anxiety MESHD, stress and depression MESHD. In this study, we compare the impact of the pandemic on two European countries: the UK and Germany, which reported their first cases within a week. 241 residents of the UK and 541 residents of Germany filled in an online survey, including questions on COVID-19 exposure, impact on financial situation and work, substance and media consumption, self-reported mental and physical health, as well as including two clinical questionnaires, the general mental health Symptom Check List-27 (SCL-27) and the Schizotypal Personality Questionnaire. Data collection was completed between 27/04/20-31/05/20. We found distinct differences between the two countries. UK responders reported a stronger direct impact on their health, financial situation and their families. UK responders had higher clinical scores on the SCL-27, with a higher percentage being above cut-off. Interestingly, however, we found that German responders were less hopeful for an end of the pandemic and more concerned about their life-stability. Generally, we found that a younger age TRANS, being female TRANS, lower education, poorer mental and physical health before the pandemic, as well as more social media and substance consumption was associated with a higher clinical risk. As 25% of all responders report a subjective worsening of the general psychological symptoms and 20-50% of responders reaching the clinical cut-off for depressive MESHD, dysthymic and anxieties HP anxieties MESHD, future pandemics require a tailored intervention system to assist not only people vulnerable for mental health problems, but also large proportions of the general public.

    Anxiety HP Anxiety MESHD, Depression and Functional impairment during the COVID-19 Pandemic among Health Care Workers

    Authors: Rajan Shrestha; Bijay Khatri; Suman Ranjitkar; Santoshi Adhikari

    doi:10.21203/ Date: 2020-08-26 Source: ResearchSquare

    BackgroundCOVID-19 is an infectious disease MESHD caused by a newly discovered coronavirus that is pandemic, with more than 338 thousand cases worldwide. Geometrically increasing numbers of cases and deaths from COVID 19 in the world, both medical staff and the public have been experiencing psychological problems MESHD, including anxiety HP anxiety MESHD, depression MESHD, and stress, which can cause disability and functional impairment of the individual. One of the most stressful situations is the unpredictability of the situation and the uncertainty of when to control the disease and the seriousness of the risk. These challenges and stress can trigger a common mental disorder MESHD. This study aimed to determine the burden of stress anxiety MESHD anxiety HP and depression MESHD among all employees of Eye and ENT hospitals.MethodologyA hospital-based cross-sectional study was carried out among all the employees of Hospital for Children TRANS Eye ENT and Rehabilitation Services Bhaktapur during the COVID-19 pandemic lockdown using an online self-administered questionnaire through Google forms. The tools were adopted from Hospital Anxiety HP Anxiety MESHD and Depression scale (HADS) Nepali version on a Likert's scale of 0 to 3 validated by Risal A. et al. and WHO Disability Assessment Schedule (WHODAS S2.0) on a Likert's scale of 1 to 5 to assess functional impairment.ResultsThe mean age TRANS (SD) of the participants (n=86) was 32.53 (7.92) years. Male TRANS and female TRANS participants was equal in number. The point prevalence SERO of anxiety HP anxiety MESHD and depression MESHD was 25.6% and 14.0%, respectively. Females TRANS had a higher prevalence SERO of both anxiety HP anxiety MESHD (39.5% vs 11.6%, p<0.01) and depression MESHD (18.6% vs 9.3%, p=0.351). The mean (SD) anxiety HP anxiety MESHD, depression MESHD and functional impairment scores were 7.27 (4.621), 5.13 (4.023) and 19.47 (6.228), respectively. Females TRANS had a very strong association with both anxiety HP anxiety MESHD (AOR=5.008 (95% CI; 1.593-15.741)) and depression MESHD (AOR=2.173 (95% CI; 0.599-7.882)). Married participants had a positive association with anxiety HP anxiety MESHD (AOR 4.379 (95% CI; 1.121-17.106)) and depression MESHD (AOR 1.542 (95% CI; 0.379-6.276)). Clinical and supporting staff both had a higher prevalence SERO of both anxiety HP anxiety MESHD (31.0% and 20.5%, p=0.265) and depression MESHD (16.7% and 11.4%, p=0.478). The mean 12-item WHO disability assessment schedule score (WHODAS 2.0) among all participants and participants with anxiety HP anxiety MESHD and depression MESHD was 19.47 (95% CI: 18.13-20.80), 21.27 (95% CI: 18.08-24.46) and 19.92 (15.28-24.56), respectively. The life activities domain of WHODAS 2.0 was significantly higher in participants with anxiety HP anxiety MESHD (1.91 vs 1.56, p<0.01) and depression MESHD (1.75 vs 1.63, p<0.001) than in those without anxiety HP anxiety MESHD.ConclusionAnxiety and depression during COVID-19 pandemic lockdown were highly prevalent both in clinical and non-clinical employees, causing mild to moderate functional impairment.

    Perceptions and Behavioral Adoptions of the Preventive Strategies from Person-to-Person Transmission TRANS of COVID-19 Among the Public in China: An Online Cross-Sectional Survey

    Authors: Xian Zhu; Yong Gan; Bo Wu; Qinyong Gou; Daikun Zheng; Chenglu Liu; Chang Xu; Zhou Tao; Hong Xu; Qian Long

    doi:10.21203/ Date: 2020-08-23 Source: ResearchSquare

    Background: The strategies adopted to prevent spreading of COVID-19 are quarantine, social distancing and isolation of infected cases. This study investigates perceptions and behavioral adoptions of COVID-19 prevention strategies among the Chinese public and identified factors predicting individual health behavior.Methods: We conducted a cross-sectional online survey between 22 February and 5 March, 2020. We approached to urban residents aged TRANS over 18 years through snowball sampling method using the Chinese social media. The Health Belief Model was adopted to guide the analysis. Bivariate and multivariate logistic regressions were used to examine impacts of modifying factors (including demographic and socio-economic characteristics) and individual beliefs on individual health behavior.Results: of 5675 valid questionnaires, 95.8% of the respondents well understood the preventive measures from COVID-19 transmission TRANS, while 79.9% of the respondents adopted the behavior advised. 45.7% of the respondents perceived severity of the disease, 75.6% of the respondents perceived benefits of social constraints measures and 62.7% reported anxiety HP anxiety MESHD during the epidemic. After adjusting for modifying factors and individual beliefs, those who were female TRANS, had better income and good knowledge on preventive measures, perceived benefits on social constraint measures and did not feel anxiety HP anxiety MESHD were more likely to adopt behaviors advised.Conclusions: The Chinese public highly accepted and adopted behaviors advised to slow down the COVID-19 epidemic. People with low income or feeling anxiety HP anxiety MESHD were less likely to adopt the behavior advised. The policy support should target on the social vulnerable groups. The psychological support should be disseminated through different means, and the consultation should be provided to those who are in need.

    Screening Supportive Care Needs, Compliance to Exercise Program, Quality of Life, and Anxiety HP Anxiety MESHD Level During the COVID-19 Pandemic in Individuals Treated with Hematopoietic Stem Cell Transplantation

    Authors: Vesile Yildiz Kabak; Songul Atasavun Uysal; Tulin Duger

    doi:10.21203/ Date: 2020-08-22 Source: ResearchSquare

    Purpose: Primary aim was to address supportive care needs, compliance to exercise program, quality of life level (QOL), and anxiety HP anxiety MESHD level during the COVID-19 pandemic in individuals treated with hematopoietic stem cell transplantation (HSCT). Secondary aim was to investigate differences in outcome measures in terms of gender TRANS and to determine associated factors with supportive care needs and compliance to exercise program during pandemic.Methods: The present study included individuals treated with HSCT and previously consulted to physical therapy. Data were collected by interviewing with participants on phone. Supportive care needs were assessed by using Supportive Care Needs Survey-Short Form 29TR. Compliance to the exercise program was recorded as percentage of walking duration to the recommended duration during the last week. The European Cancer Research and Treatment Organization Quality of Life Questionnaire-Cancer30 was used to assess QOL. The State-Trait Anxiety HP Anxiety MESHD Inventory-I and Visual Analogue Scale were used to assess anxiety HP anxiety MESHD level. Results: Totally 106 individuals were included. The psychological and physical supportive care needs were predominant in participants. Compliance to exercise program was low during the pandemic. Anxiety HP Anxiety MESHD level was low, yet anxiety HP anxiety MESHD about COVID-19 was moderate severity in participants. Supportive care needs were correlated with anxiety HP anxiety MESHD level, performance SERO level, duration after HSCT, and QOL (p˂0.05). Compliance to exercise program was associated with performance SERO level and QOL (p˂0.05). Conclusion: Our results offer supportive telehealth interventions should be considered during the COVID-19 pandemic for individuals treated with HSCT to decrease unmet supportive care needs and anxiety HP anxiety MESHD, to increase QOL, and to reduce isolation related physical inactivity.

    The Mental Health of Healthcare Staff during the COVID-19 Pandemic: It Depends on How Much They Work and Their Age TRANS

    Authors: Xingzi Xu; Stephen X. Zhang; Asghar Afshar Jahanshahi; Jizhen Li; Afsaneh Bagheri; Khaled Nawaser; Annalisa Ruggeri; Marina Sironi; Peter Radermacher; Panagiotis Skendros; Konstantinos Ritis; Ilenia Manfra; Simona Iacobelli; Markus Huber-Lang; Bo Nilsson; Despina Yancopoulou; E. Sander Connolly; Cecilia Garlanda; Fabio Ciceri; Antonio M. Risitano; Rodrigo T. Calado; John D. Lambris

    doi:10.1101/2020.08.18.20173500 Date: 2020-08-21 Source: medRxiv

    Background: Healthcare staff are the forefront of fight against COVID-19 and they are under enormous pressure due to the fast growth in the number and severity of infected cases. This creates their mental issues such as distress, depression MESHD and anxiety HP anxiety MESHD. Exploring healthcare staff's mental health during the pandemic contributes to improving their persistence in the growing challenges created by COVID-19 and enabling effective management of their mental health. Methods: An online survey of 280 healthcare staff in all the 31 provinces of Iran was conducted during April 5 to 20, 2020. The survey assessed staff's distress, depression MESHD and anxiety HP anxiety MESHD in the COVID-19 pandemic. Results: Nearly a third of healthcare staff suffered from distress, depression MESHD and anxiety HP anxiety MESHD. Females TRANS and more educated healthcare staff were more likely to experience distress. Compared to personnel who did not have COVID-19, those who were unsure whether they had COVID-19 were more likely to experience distress and depression MESHD. The number of COVID-19 cases among the staff's colleagues or friends TRANS positively predicted their anxiety HP anxiety MESHD. Compared to radio technologists, doctors were less likely to experience distress and anxiety HP anxiety MESHD. Technicians and obstetrics experienced less anxiety HP anxiety MESHD. Analysis the interaction between weekly working days and age TRANS of the staff indicated the chance of experiencing distress and depression MESHD varied greatly by working days among younger but not older healthcare staff. Conclusion: Exploring the potential predictors of mental health issues assists healthcare organizations to develop approaches to prevent and decrease the issues among staff and improve their task performance SERO in sever crises such as COVID-19, so they can stay motivated in the COVID-19 pandemic. It is useful to identify more working characteristic predictors for healthcare staff at different ages TRANS.

    COVID-19 pandemic and self-reported symptoms of depression MESHD, anxiety HP anxiety MESHD, and stress among health care workers in Ethiopia MESHD

    Authors: kemal Jemal; Berhanu Senbeta; Tinsae Abeya Geleta; Mukemil Awol

    doi:10.21203/ Date: 2020-08-19 Source: ResearchSquare

    BackgroundThe Coronavirus Diseases 2019 (COVID-19) pandemic has become a major problem in many of the world nations including Ethiopia. Moreover, it is a public health emergency of the community concern and poses a mental health problem to health care workers (HCWs). Therefore, this study aimed to assess the level of self-reporting symptoms of depression MESHD, anxiety HP anxiety MESHD, and stress during the COVID-19 pandemic among healthcare workers in Ethiopia.MethodsAn institutional-based cross-sectional study was conducted using an online survey from June 25, 2020, to July 25, 2020, in Ethiopia. The data were collected using a self-reported Depression MESHD, Anxiety HP Anxiety MESHD, and Stress Scale (DASS-21). Data were cleaned, coded, and entered using Epi info version 7.5.1 and exported for analyzed to the Social Science package software Version 23 Statistical Package. Moreover, multiple logistic regression analysis was used to identify the associated factors at p-value less than 0.05.ResultsA total of 816 HCWs responded to self-reporting questions. From HCWs who screened positive for depression MESHD, anxiety HP anxiety MESHD, and stress; 60.3%, 78%, and 33.8% of them had scored moderate to extremely severe symptoms of depression MESHD, anxiety HP anxiety MESHD, and stress respectively. Females TRANS, HCWs who working in Oromiya Specialized Zone, medical laboratory professionals, and HCWs who have working in the COVID-19 treatment isolation department were significantly associated with depression MESHD, anxiety HP anxiety MESHD, and stress.ConcussionIn this study, health care workers had reported a high prevalence SERO of depression MESHD, anxiety HP anxiety MESHD, and stress symptoms. Female TRANS gender TRANS, Oromiya especial zone, medical laboratory professionals, and HCWs who have working in the COVID-19 treatment isolation centers were significantly associated with depression MESHD, anxiety HP anxiety MESHD, and stress. Psychological intervention for health care workers in central Ethiopia needs special attention.

    Impacts of the COVID-19 Pandemic on Life of Higher Education Students: A Global Perspective

    Authors: Aleksander Aristovnik; Damijana Keržič; Dejan Ravšelj; Nina Tomaževič; Lan Umek

    id:10.20944/preprints202008.0246.v2 Date: 2020-08-19 Source:

    The paper presents the most comprehensive and large-scale study to date on how students perceive the impacts of the COVID-19 crisis on various aspects of their lives on a global level. With a sample of 30,383 students from 62 countries, the study reveals that amid the worldwide lockdown and transition to online learning students were most satisfied with the support provided by teaching staff and their universities’ public relations. Still, deficient computer skills MESHD and the perception of a higher workload prevented them from perceiving their own improved performance SERO in the new teaching environment. Students were mainly concerned about issues to do with their future professional career and studies, and experienced boredom, anxiety HP anxiety MESHD and frustration. The pandemic has led to the adoption of particular hygienic behaviours (e.g. wearing masks, washing hands) and discouraged certain daily practices (e.g. leaving home, shaking hands). Students were also more satisfied with the role played by hospitals and universities during the epidemic compared to the government and banks. The findings also show that students with selected socio-demographic characteristics ( male TRANS, part-time, first level, applied sciences, lower living standard, from Africa or Asia) were generally more strongly affected by the pandemic since they were significantly less satisfied with their academic work/life. Key factors influencing students' satisfaction with the role of their university are also identified. Policymakers and higher education institutions around the world may benefit from these findings while formulating policy recommendations and strategies to support students during this and any future pandemics.

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MeSH Disease
Human Phenotype

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