Corpus overview


MeSH Disease

Human Phenotype

Anxiety (140)

Insomnia (7)

Pain (7)

Sleep disturbance (6)

Fever (6)


    displaying 31 - 40 records in total 140
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    Perceptions and Behavioral Adoptions of the Preventive Strategies from Person-to-Person Transmission TRANS of COVID-19 among the Public in China: An Online Cross-Sectional Survey

    Authors: Xian Zhu; Yong Gan; Bo Wu; Qinyong Gou; Daikun Zheng; Chenglu Liu; Chang Xu; Zhou Tao; Hong Xu; Qian Long

    doi:10.21203/ Date: 2020-08-06 Source: ResearchSquare

    Background: The strategies adopted to prevent spreading of COVID-19 are quarantine, social distancing and isolation of infected cases. This study investigates perceptions and behavioral adoptions of COVID-19 prevention strategies among the Chinese public and identified factors predicting individual health behavior.Methods: We conducted a cross-sectional online survey between 22 February and 5 March, 2020. We approached to urban residents aged TRANS over 18 years through snowball sampling method using the Chinese social media. The Health Belief Model was adopted to guide the analysis. Bivariate and multivariate logistic regressions were used to examine impacts of modifying factors (including demographic and socio-economic characteristics) and individual beliefs on individual health behavior.Results: of 5675 valid questionnaires, 95.8% of the respondents well understood the preventive measures from COVID-19 transmission TRANS, while 79.9% of the respondents adopted the behavior advised. 45.7% of the respondents perceived severity of the disease, 75.6% of the respondents perceived benefits of social constraints measures and 62.7% reported anxiety HP anxiety MESHD during the epidemic. After adjusting for modifying factors and individual beliefs, those who were female TRANS, had better income and good knowledge on preventive measures, perceived benefits on social constraint measures and did not feel anxiety HP anxiety MESHD were more likely to adopt behaviors advised.Conclusions: The Chinese public highly accepted and adopted behaviors advised to slow down the COVID-19 epidemic. People with low income or feeling anxiety HP anxiety MESHD were less likely to adopt the behavior advised. The policy support should target on the social vulnerable groups. The psychological support should be disseminated through different means, and the consultation should be provided to those who are in need.

    Level of anxiety HP anxiety MESHD caused by the coronavirus (COVID-19) pandemic among dentists in Poland.

    Authors: Ewa Rusyan; Agnieszka Mielczarek; Agnieszka Kapała; Kamil Adamczyk; Robert Piec; Barbara Szykuła- Piec

    doi:10.21203/ Date: 2020-08-03 Source: ResearchSquare

    Background: The early information on both the speed and high morbidity rate and, above all, mortality, triggered the symptoms of COVID-19-related panic and anxiety HP anxiety MESHD. Dentists were listed in the top five professions with the highest risk of transmission TRANS of the virus. The paper aimed to assess the level of anxiety HP anxiety MESHD among dentists in Poland. Methods: A cross-sectional study was conducted via an online survey questionnaire. The study used a tool developed by the team of Ahorsu et al. The COVID-19 Fear Scale (FCV-19S) translated into the Polish language. The online questionnaire was completed by 356 dentists. Results: In the studied population of dentists, the perceived level of anxiety HP anxiety MESHD associated with COVID -19 should be considered relatively low. Both gender TRANS and work experience had no significant impact on their level. When the respondents had children TRANS, lived with the elderly TRANS, or looked after them the observed level of anxiety HP anxiety MESHD was higher and physical symptoms such as sweating palms and increased heart rate occurred.Conclusion: Despite the high risk of infection TRANS risk of infection TRANS infection MESHD, the tested low level of anxiety HP anxiety MESHD among dentists is a positive predictor of the appropriate level of medical services provided by this group of doctors. 

    Sexual Function, Mental Health, and Quality of Life Under Strain of COVID-19 Pandemic in Iranian Pregnant and Lactating Women: A Cross-sectional Study

    Authors: Negin Mirzaei; shahideh Jahanian Sadatmahalleh; Mahnaz Bahri Khomami; Ashraf Moini; Anoshirvan Kazemnejad

    doi:10.21203/ Date: 2020-08-03 Source: ResearchSquare

    Background The impact of COVID-19 pandemic on mental health of pregnant and lactating women is unclear. This study aimed to assess the impact of COVID-19 on psychological health, sexual function, and quality of life (QoL) in Iranian pregnant and lactating women and compare the results with non-pregnant /lactating (as the control group).Method: This cross-sectional study was carried out on pregnant and lactating women as case groups, with non-pregnant /lactating women as control. Patients were asked to complete three questionnaires: Hospital Anxiety HP Anxiety MESHD and Depression Scale (HADS), Female TRANS Sexual Function Index (FSFI), and Short-Form Health Survey (SF-12). One-way ANOVA was used to reveal the statistical differences between the three groups.Result The mean age TRANS of patients was 20.81 ± 5.92 years old. Evaluation of the three groups with regard to HADS MESHD and SF-12 showed that all mean values were lower in pregnant women than in other groups. Also, the differences in scores in the three groups were statistically significant (P˂0.001). The comparison of FSFI scores showed that the mean of all domain and total scores were significantly lower in pregnant women compared with other groups. The differences between the three groups were statistically significant during desire, arousal, orgasm, pain HP pain MESHD, and total score (P˂0.001).Conclusion The COVID-19 epidemic increases the risk of depression MESHD, anxiety HP anxiety MESHD, FSD, and lowers QoL in pregnant and lactating women, with the general population. This suggests the urgent need for psychological intervention in the maternal population during the epidemic.

    Anxiety HP Anxiety MESHD Amongst Physicians During COVID-19: Cross-Sectional Study in Pakistan

    Authors: Qaisar Khalid Mahmood; Sara Rizvi Jafree; Aisha Jalil; Florian Fischer; Syed Mujtaba Hasnain Nadir

    doi:10.21203/ Date: 2020-07-30 Source: ResearchSquare

    Background: Ensuring safety and wellbeing of healthcare providers is crucial, particularly during times of a pandemic. In this study, we aim to identify the determinants of anxiety HP anxiety MESHD in physicians on duty in coronavirus wards or quarantine centers. Methods: We conducted a cross-sectional quantitative survey with an additional qualitative item. Overall, 103 physicians completed the questionnaire. T-test results revealed significant associations between gender TRANS and anxiety HP anxiety MESHD. Results: Structural equation modeling identified that high workload contributed to greater exhaustion (β=0.41, R2=0.17, p<0.001) and greater family strain (β=0.47, R2=0.22, p<0.001). Exhaustion (β=0.17, p<0.005), family strain (β=0.34, p<0.001), and feelings of protection (β=-0.30, p<0.001) significantly explained anxiety HP anxiety MESHD (R2=0.28). Qualitative findings further identified specific needs of physicians with regard to protective equipment, compensation, quarantine management, resource allocation, security and public support, governance improvement, and health sector development. Conclusions: It is imperative to improve governmental and social support for healthcare providers during the corona pandemic. Immediate attention is needed to reduce anxiety HP anxiety MESHD, workload, and family strain in frontline practitioners treating coronavirus patients, and to improve their (perceptions of) protection. This is a precondition for patient safety.

    Persistent fatigue HP fatigue MESHD following SARS-CoV-2 infection MESHD is common and independent of severity of initial infection MESHD

    Authors: Liam Townsend; Adam H Dyer; Karen Jones; Jean Dunne; Rachel Kiersey; Fiona Gaffney; Laura O'Connor; Aoife Mooney; Deirdre Leavy; Katie Ridge; Catherine King; Fionnuala Cox; Kate O'Brien; Joanne Dowds; Jamie Sugrue; David Hopkins; Patricia Byrne; Tara Kingston; Cliona Ni Cheallaigh; Parthiban Nadarajan; Anne Marie McLaughlin; Nollaig M Bourke; Colm Bergin; Cliona O'Farrelly; Ciaran Bannan; Niall Conlon

    doi:10.1101/2020.07.29.20164293 Date: 2020-07-30 Source: medRxiv

    Fatigue HP is a common symptom in those presenting with symptomatic COVID-19 infection MESHD. However, it is unknown if COVID-19 results in persistent fatigue HP fatigue MESHD in those recovered from acute infection MESHD. We examined the prevalence SERO of fatigue HP fatigue MESHD in individuals recovered from the acute phase of COVID-19 illness using the Chalder Fatigue HP Score (CFQ-11). We further examined potential predictors of fatigue HP fatigue MESHD following COVID-19 infection MESHD, evaluating indicators of COVID-19 severity, markers of peripheral immune activation and circulating pro-inflammatory cytokines. Of 128 participants (49.5 {+/-} 15 years; 54% female TRANS), more than half reported persistent fatigue HP (52.3%; 45/128) at 10 weeks (median) after initial COVID-19 symptoms. There was no association between COVID-19 severity (need for inpatient admission, supplemental oxygen or critical care) and fatigue HP fatigue MESHD following COVID-19. Additionally, there was no association between routine laboratory markers of inflammation MESHD and cell turnover (leukocyte, neutrophil or lymphocyte counts, neutrophil-to-lymphocyte ratio, lactate dehydrogenase, C-reactive protein) or pro-inflammatory molecules (IL-6 or sCD25) and fatigue HP fatigue MESHD post COVID-19. Female TRANS gender TRANS and those with a pre-existing diagnosis of depression MESHD/ anxiety HP anxiety MESHD were over-represented in those with fatigue HP fatigue MESHD. Our findings demonstrate a significant burden of post-viral fatigue HP fatigue MESHD in individuals with previous SARS-CoV-2 infection MESHD after the acute phase of COVID-19 illness. This study highlights the importance of assessing those recovering from COVID-19 for symptoms of severe fatigue HP fatigue MESHD, irrespective of severity of initial illness, and may identify a group worthy of further study and early intervention.

    When COVID-19 Enters in a Community Setting: An Exploratory Qualitative Study of Community Perspectives on COVID-19 Affecting Mental Well-Being

    Authors: Naureen Akber Ali; Anam Shahil Feroz; Noshaba Ali; Ridah Feroz; Salima Nazim Meghani; Sarah Saleem

    doi:10.21203/ Date: 2020-07-29 Source: ResearchSquare

    Background: The COVID-19 pandemic has certainly resulted in an increased level of anxiety HP anxiety MESHD and fear among the general population related to its management and infection spread. Due to the current unprecedented situation the normal routine life of every individual has been hindered which may cause florid mental distress. Considering the relevance of present circumstances we explored perceptions and attitudes of community members towards COVID-19 pandemic and its impact on their mental well-being. Methods: We conducted an exploratory qualitative study using a purposive sampling approach, at two communities of Karachi, Pakistan. In-depth interviews were conducted with community members including, young adults TRANS, middle- age TRANS adults TRANS, and older adults TRANS of both genders TRANS. Study data was analyzed manually using the conventional content analysis technique. Results: A total of 27 in-depth interviews were conducted, between May and June, 2020. Three overarching themes were identified: (I) Impact of COVID-19 on mental health of the general communities; (II) Current coping mechanisms to adapt to the new reality; and (III) Recommendations to address mental health of communities. Generally community members underwent increased anxiety HP anxiety MESHD and fear due to the contagious nature of the virus. Alongside, social, financial and religious repercussions of the pandemic have also heightened psychological distress among community members. However, community members were able to point out some of the coping mechanisms such as getting closer to God, connecting with family, participating in mental health sessions and resetting lives by indulging in diverse activities. Simultaneously, they also recommended the need of remote mental health services for elders and continuous efforts by the government to address mental health needs of the community at larger scale.Conclusion: COVID-19-associated mental health consequences have hit every individual in the society. The study finding has the potentialto guide the development of context-specific innovative mental health programs to overcome the pandemic repercussions.

    Mental Health Impacts for International Students During the COVID-19 Pandemic in China

    Authors: Xiaoping Wang; Khamlesh Hujjaree; Fanglan Wang

    doi:10.21203/ Date: 2020-07-26 Source: ResearchSquare

    The outbreak of Coronavirus disease MESHD 2019 (COVID-19), has led to the quarantine of many residents in their homes worldwide. Some of these people might develop mental health problems, and many solutions have been put in place to address the mental health issues of patients and health professionals affected by the disease. However, not much attention has been given to international students studying in China. The present study aims to conduct an online survey to investigate the mental health status of international students from Changsha city, China.Materials and Methods: A WeChat-based survey program comprised of questions on demographic information gender TRANS, grade year, duration and status of quarantine, duration of sleep, worries about graduation, being able to go to school and presence or absence of a sense of security; as well as questions from the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety HP Anxiety MESHD Disorder-7 (GAD-7) scale and State-Trait Anxiety HP Anxiety MESHD Inventory(STAI).Results: The prevalence SERO of depression MESHD was 59.4% and the prevalence SERO of anxiety HP anxiety MESHD was 37.8%. The STAI-Y1 STATE scores had a mean value (mean) of 41.42, standard deviation (S.D) of 10.89 and STAI-Y2 TRAIT scores had a mean value (mean) of 41.85, standard deviation (S.D) of 11.13.  The risk factors of anxiety HP anxiety MESHD or depression MESHD were Sleep duration, worrying about graduation in varying degrees, School time, and feeling secure in varying degrees. Higher the Patient Health Questionnaire-9 score and higher Generalized Anxiety HP Anxiety MESHD Disorder-7 score and higher STAI-Y1 STATE scores were associated with higher STAI-Y2 TRAIT scores.Conclusion: The present study implies that the university needs to consider planning for acute and long-term psychological help services for international students.

    Explainable-Machine-Learning to discover drivers and to predict mental illness during COVID-19

    Authors: Indra Prakash Jha; Raghav Awasthi; Ajit Kumar; VIBHOR KUMAR; Tavpritesh Sethi

    doi:10.1101/2020.07.19.20157164 Date: 2020-07-21 Source: medRxiv

    COVID-19 pandemic has deeply affected the global economy, education, and travel TRANS and stranded people in their respective zones. Most importantly, it has claimed more than half a million lives and is poised to create long and short term consequences through mental health impairment. Identification of important factors affecting mental health can help people manage emotional, psychological, and social well-being. Here, we focus on identifying factors that have a significant impact on mental health during COVID pandemics. In this study, We have used a survey of 17764 adults TRANS in the USA at different age groups TRANS, genders TRANS, and socioeconomic statuses. Through initial statistical analysis followed by Bayesian Network inference, we have identified key factors affecting Mental health during the COVID pandemic. Integrating Bayesian networks with classical machine learning approaches lead to effective modeling of the level of mental health. Overall, females TRANS are more stressed than males TRANS, and people of age-group TRANS 18-29 are more vulnerable to anxiety HP anxiety MESHD than other age groups TRANS. Using the Bayesian Network Model, we found that people with the chronic medical condition of mental illness MESHD are more prone to mental disorders MESHD during COVID age TRANS. The new realities of working from home, home-schooling, and lack of communication with family/ friends TRANS/neighbors induces mental pressure. Financial assistance from social security helps in reducing mental stress during COVID generated economic crises. Finally, using supervised ML models, we predicted the most mentally vulnerable people with ~80% accuracy.


    Authors: Max Denning; Ee Teng Goh; Benjamin Tan; Abhiram Kanneganti; Melanie Almonte; Alasdair Scott; Guy Martin; Jonathan Clarke; Viknesh Sounderajah; Sheraz Markar; Jan Przybylowicz; Yiong Huak Chan; Ching-Hui Sia; Ying Xian Chua; Kang Sim; Lucas Lim; Lifeng Tan; Melanie Tan; Vijay Sharma; Shirley Ooi; Jasmine Winter Beatty; Kelsey Flott; Sam Mason; Swathikan Chidambaram; Seema Yalamanchili; Gabriela Zbikowska; Jaroslaw Fedorowski; Grazyna Dykowska; Mary Wells; Sanjay Purkayastha; James Kinross

    doi:10.1101/2020.07.16.20155622 Date: 2020-07-18 Source: medRxiv

    Background The Covid-19 pandemic has placed unprecedented pressure on healthcare systems and workers around the world. Such pressures may impact on working conditions, psychological wellbeing and perception of safety. In spite of this, no study has assessed the relationship between safety attitudes and psychological outcomes. Moreover, only limited studies have examined the relationship between personal characteristics and psychological outcomes during Covid-19. Methods From 22nd March 2020 to 18th June 2020, healthcare workers from the United Kingdom, Poland, and Singapore were invited to participate using a self-administered questionnaire comprising the Safety Attitudes Questionnaire (SAQ), Oldenburg Burnout Inventory (OLBI) and Hospital Anxiety HP Anxiety MESHD and Depression Scale (HADS) to evaluate safety culture, burnout and anxiety HP anxiety MESHD/depression. Multivariate logistic regression was used to determine predictors of burnout, anxiety HP anxiety MESHD and depression. Results Of 3,537 healthcare workers who participated in the study, 2,364 (67%) screened positive for burnout, 701 (20%) for anxiety HP anxiety MESHD, and 389 (11%) for depression MESHD. Significant predictors of burnout included patient-facing roles: doctor (OR 2.10; 95% CI 1.49-2.95), nurse (OR 1.38; 95% CI 1.04-1.84), and other clinical staff (OR 2.02; 95% CI 1.45-2.82); being redeployed (OR 1.27; 95% CI 1.02-1.58), bottom quartile SAQ score (OR 2.43; 95% CI 1.98-2.99), anxiety HP anxiety MESHD (OR 4.87; 95% CI 3.92-6.06) and depression MESHD (OR 4.06; 95% CI 3.04-5.42). Factors significantly protective for burnout included being tested for SARS-CoV-2 (OR 0.64; 95% CI 0.51-0.82) and top quartile SAQ MESHD score (OR 0.30; 95% CI 0.22-0.40). Significant factors associated with anxiety HP anxiety MESHD and depression, included burnout, gender TRANS, safety attitudes and job role. Conclusion Our findings demonstrate a significant burden of burnout, anxiety HP anxiety MESHD, and depression MESHD amongst healthcare workers. A strong association was seen between SARS-CoV-2 testing, safety attitudes, gender TRANS, job role, redeployment and psychological state. These findings highlight the importance of targeted support services for at risk groups and proactive SARS-CoV-2 testing of healthcare workers.

    An overview of current mental health in the general population of Australia during the COVID-19 pandemic: Results from the COLLATE project

    Authors: Susan Rossell; Erica Neill; Andrea Phillipou; Eric Tan; Wei Lin Toh; Tamsyn Van Rheenen; Denny Meyer

    doi:10.1101/2020.07.16.20155887 Date: 2020-07-18 Source: medRxiv

    The novel coronavirus disease MESHD (COVID-19) poses significant mental health challenges globally; however, to date, there is limited community level data. This study reports on the first wave of data from the COLLATE project (COvid-19 and you: mentaL heaLth in AusTralia now survEy), an ongoing study aimed at understanding the impact of the COVID-19 pandemic on the mental health and well-being of Australians. This paper addresses prevailing primary concerns related to the COVID-19 pandemic, current levels of negative emotions and risk factors predicting these negative emotions. On April 1st to 4th 2020, 5158 adult TRANS members of the Australian general public completed an online survey. Participants ranked their top ten current primary concerns about COVID-19, and completed standardized measures to ascertain levels of negative emotions (specifically, depression MESHD, anxiety HP anxiety MESHD and stress). Socio-demographic information was also collected and used in the assessment of risk factors. The top three primary concerns were all related to the health and well-being of family and loved ones. As expected, levels of negative emotion were exceptionally high. Modelling of predictors of negative emotions established several risk factors related to demographic variables, personal vulnerabilities, financial stresses, and social distancing experiences; particularly being young, being female TRANS, or having a mental illness diagnosis. The data provides important characterization of the current mental health of Australians during the COVID-19 pandemic. Critically MESHD, it appears that specific groups in the Australian community may need special attention to ensure their mental health is protected during these difficult times. The data further suggests the need for immediate action to combat high levels of psychological distress, along with the exacerbation of mental health conditions, in relation to the COVID-19 pandemic in Australia. These results may provide some direction for international researchers hoping to characterize similar issues in other countries.

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MeSH Disease
Human Phenotype

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