Corpus overview


Overview

MeSH Disease

Fever (1)

Cough (1)

Fatigue (1)

Dyspnea (1)

Lymphopenia (1)


Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Clinical Characteristics of 20,662 Patients with COVID-19 in mainland China: A Systemic Review and Meta-analysis

    Authors: Chong Tang; Keshi Zhang; Wenlong Wang; Zheng Pei; Zheng Liu; Ping Yuan; Zhenpeng Guan; Jin Gu

    doi:10.1101/2020.04.18.20070565 Date: 2020-04-23 Source: medRxiv

    Coronavirus disease 2019 (COVID-19) is a global pandemic and has been widely reported; however, a comprehensive systemic review and meta-analysis has not been conducted. We systematically investigated the clinical characteristics of COVID-19 in mainland China to guide diagnosis and treatment. We searched the PubMed, Embase, Scopus, Web of Science, Cochrane Library, bioRxiv, medRxiv, and SSRN databases for studies related to COVID-19 published or preprinted in English or Chinese from January 1 to March 15, 2020. Clinical studies on COVID-19 performed in mainland China were included. We collected primary outcomes including signs and symptoms, chest CT imaging, laboratory tests, and treatments. Study selection, data extraction, and risk of bias assessment were performed by two independent reviewers. Qualitative and quantitative synthesis was conducted, and random-effects models were applied to pooled estimates. This study is registered with PROSPERO (number CRD42020171606). Of the 3624 records identified, 147 studies (20,662 patients) were analyzed. The mean age TRANS of patients with COVID-19 was 49.40 years, 53.45% were male TRANS, and 38.52% had at least one comorbidity. Fever HP Fever MESHD and cough HP cough MESHD were the most common symptoms, followed by fatigue HP fatigue MESHD, expectoration, and shortness of breath MESHD. Most patients with COVID-19 had abnormal chest CT findings with ground glass opacity (70.70%) or consolidation (29.91%). Laboratory findings shown lymphopenia HP lymphopenia MESHD, increased lactate dehydrogenase, increased infection-related indicators, and fibrinolytic hyperactivity HP. Antiviral therapy, antibiotic therapy, and corticosteroids were administered to 89.75%, 79.13%, and 35.64% of patients, respectively. Most clinical characteristics of COVID-19 are non-specific. Patients with suspected should be evaluated by virological assays and clinically treated.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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