Corpus overview


Overview

MeSH Disease

Infections (2)

Fever (2)

Cough (2)

Lethargy (2)

Fatigue (1)


Human Phenotype

Fever (2)

Cough (2)

Lethargy (2)

Fatigue (1)

Hypertension (1)


Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Prolonged nucleic acid conversion and false-negative RT-PCR results in Indonesian patients with COVID-19: A case series

    Authors: Ika Trisnawati; Riat Al Khair; Aditya Rifqi Fauzi; Gunadi

    doi:10.21203/rs.3.rs-39961/v1 Date: 2020-07-02 Source: ResearchSquare

    Background: Prolonged nucleic acid conversion and false-negative results of real-time reverse transcription polymerase chain reaction (RT-PCR) might occur in some patients with COVID-19 rather than recurrence of infection MESHD. Here, we reported four cases of COVID-19 with prolonged nucleic acid conversion and false-negative results of RT-PCR in our institution.Case presentation: Case 1: A 36-year-old- male TRANS patient complained of coughing HP up phlegm one week before admission. His chest X-rays showed mild pneumonia HP pneumonia MESHD in the right lung. His swab test was confirmed positive for SARS-Cov-2. Besides the last two consecutive negative results, he also had negative results of RT-PCR twice (the 6th and 8th tests) from a total of 11 swab tests. Case 2: A 54-year-old- male TRANS patient complained of shortness of breath MESHD that worsened with activity. He had a comorbidity of diabetes MESHD. His chest X-rays showed inhomogeneous opacity on bilateral paracardial and lateral aspects. His swab test was confirmed positive for SARS-Cov-2. Besides the last two consecutive negative results, he also had negative results of RT-PCR once (the 5th test) from a total of 8 swab tests. Case 3: A 47-year-old man presented with complaints of fever HP fever MESHD, cough HP cough MESHD, sore throat, and diarrhea HP diarrhea MESHD. He had comorbidities of asthma HP asthma MESHD and heart rhythm disorders MESHD. His chest X-rays showed bilateral pneumonia HP pneumonia MESHD. His swab test was confirmed positive for SARS-Cov-2. Besides the last two consecutive negative results, he also showed negative results of RT-PCR twice (the 4th and 6th tests) from a total of 11 swab tests. Case 4: A 56-year-old- female TRANS complained of lethargy HP lethargy MESHD and diarrhea HP diarrhea MESHD. She has a history of hyperthyroidism HP hyperthyroidism MESHD. His chest X-rays showed bilateral pneumonia HP pneumonia MESHD. She was confirmed positive for SARS-Cov-2. Besides the last two consecutive negative results, she also had negative results of RT-PCR twice (the 2nd and 10th tests) from a total of 14 swab tests.Conclusions: Our cases further confirmed TRANS the occurrence of prolonged nucleic acid conversion and the possibility of false negative results of RT-PCR in patients with COVID-19 instead of recurrence of infection MESHD. These findings might have an implication on the management of patients with COVID-19 who have already clinically and radiologically recovered, particularly related to subsequent spreading of the infection MESHD in the community.

    A meta-analysis of 2019 novel corona virus patient clinical characteristics and comorbidities

    Authors: Subodh Sharma Paudel

    doi:10.21203/rs.3.rs-21831/v1 Date: 2020-04-07 Source: ResearchSquare

    IntroductionBeing a new variant of coronavirus, detailed information regarding the virulence, its clinical characters, high risk individuals are yet to be defined. This study was done with the objective of finding out clinical features of corona infection MESHD and also studies what are the comorbidities that are associated with it.MethodsThis is a single arm meta-analysis in which relevant data were derived from searches in PubMed. It includes study papers which were written in English language and their completely published article is found. Seven articles published from 24th Jan to 16th March, 2020 are included in this study. ResultsThe total number of patients was 1786 with 1044 males TRANS and 742 females TRANS with male TRANS to female TRANS ratio of 1.4:1. The median age TRANS of patients was 41 years). Fever HP Fever MESHD was present in 88.8% cases. Dry Cough HP in 68% followed by fatigue HP fatigue MESHD in 33%. Hypertension HP Hypertension MESHD (15.8%) is the most common comorbidity followed by cardio and cerebrovascular condition (11.7%). ConclusionPatients often presented with symptoms of fever HP fever MESHD, dry cough MESHD cough HP, lethargy HP lethargy MESHD and fatigue HP fatigue MESHD, muscle pain MESHD pain HP, productive cough HP. Similarly, patients with previous history of HTN, DM MESHD, COPD MESHD, cardio and cerebrovascular condition, immune-deficient states are at high risk of developing into the severe COVID-19 infection MESHD.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).
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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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