Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Analysis of myocardial enzyme spectrum in 230 COVID-19 patients of Chongqing, China.

    Authors: Jiao CaiLing; Li Wen Fa; Xie YeHong; Miao JiaWei; Wu YunFang; Tan WanNing; Li Jing; Zhang JianRong

    doi:10.21203/rs.3.rs-23849/v1 Date: 2020-04-19 Source: ResearchSquare

    Background A novel coronavirus disease COVID-19 outbreak caused pandemic in China and worldwide. In addition to pneumonia HP pneumonia MESHD, Cardiac failure MESHD is also a clinical outcome of coronavirus (COVID-19) patients and one of the leading causes for the death of COVID-19 patients. This study focused on a spectrum of cardiac enzymes to provide biomarkers for the severity of cardiomyopathy HP cardiomyopathy MESHD, and provide guidance of clinical treatment.Methods 230 coronavirus patients (182 mild and 48 severe cases) enrolled in Three Gorges Hospital of Chongqing University from January to March 2020 were analyzed for a spectrum of cardiac injury MESHD enzymes including α-hydroxybutyric dehydrogenase (αHBDH), lactic acid dehydrogenase (LDH), creatine kinase (CK), and creatine kinase isoenzyme (CK-MB).Results The severe cases had significantly higher myocardial enzyme levels than mild cases, regardless of male TRANS and females TRANS. Males TRANS appeared to be more susceptible than females TRANS to COVID-19 induced heart injury MESHD, having higher CK and CK-MB in mild cases, and higher αHBDH and LDH levels in severe cases. Age TRANS is also a susceptible factor to COVID-19, but affected males TRANS were younger than females TRANS.Conclusions This study reveals that the heart is also a major target of COVID-19 infection MESHD, and myocardial enzyme spectrum assays could help the diagnosis, prognosis and guide the treatments to prevent heart failure MESHD in COVID-19 patients.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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