Stressful situations can cause changes in individual food choices, most notably, choices of highly rewarding foods that are high in fat or sugar. Few studies have examined how a population's food choices change during a country-wide stress-inducing event such as the beginning of the COVID-19 stay-at-home orders in the United States. Food data from a digital behavior change weight loss HP
program, which includes an interface for logging meals, were analyzed to assess self-reported food choices from March 5-March 11 ("pre-COVID") and during the first week of the COVID-19 lockdown (March 12-March 18; "during-COVID"). The final sample consisted of 381,564 participants: 318,076 (83.4%) females TRANS
, the majority who were aged TRANS
45-65 years (45.2%). Results indicate that self-reported servings of fresh fruit and vegetable intake decreased from pre- to during-COVID, while intake of red meat and starchy vegetables increased. More men than women increased their intake of red meat and processed meat. There was less overall change in fruit and vegetable consumption in participants aged TRANS
66 and older, compared to younger participants ( aged TRANS
18-35). The percentage of older participants who reported lean meat and starchy vegetable intake increased, but these groups had a negligible change in younger subjects. More subjects aged TRANS
18-35 years reduced their intake of caffeine, desserts, lean meat and salads compared to older participants. No changes were observed in terms of snack or alcoholic beverage intake logged. In conclusion, this study of 381,564 US participants revealed that intake of particular food groups were altered during the first weeks of COVID lockdown.