Corpus overview


MeSH Disease

Human Phenotype



There are no seroprevalence terms in the subcorpus

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    COVID-19 related concerns of people with long-term respiratory conditions: A qualitative study

    Authors: Keir Elmslie James Philip; Bradley Lonergan; Andrew Cumella; Joe Farrington-Douglas; Michael Laffan; Nicholas S Hopkinson

    doi:10.1101/2020.06.19.20128207 Date: 2020-06-26 Source: medRxiv

    BACKGROUND The COVID-19 pandemic is having profound psychological impacts on populations globally, with increasing levels of stress, anxiety HP anxiety MESHD, and depression MESHD being reported, especially in people with pre-existing medical conditions who appear to be particularly vulnerable. There are limited data on the specific concerns people have about COVID-19 and what these are based on. METHODS The aim of this study was to identify and explore the concerns of people with long-term respiratory conditions in the UK regarding the impact of the COVID-19 pandemic and how these concerns were affecting them. We conducted a thematic analysis of free text responses to the question 'What are your main concerns about getting coronavirus?', which was included in the British Lung Foundation/ Asthma HP UK (BLF-AUK) partnership COVID-19 survey, conducted between the 1st and 8th of April. This was during the 3rd week of the UK's initial social distancing measures. RESULTS 7,039 responses were analysed, with respondents from a wide range of ages TRANS, gender TRANS, and all UK nations. Respondents reported having asthma HP (85%), COPD MESHD (9%), bronchiectasis HP (4%), interstitial lung disease MESHD (2%), or 'other' lung diseases (e.g. lung cancer MESHD) (1%). Four main themes were identified: 1) vulnerability to COVID-19; 2) anticipated experience of contracting COVID-19; 3) wide-reaching uncertainty; and 4) inadequate national response. CONCLUSIONS The COVID-19 pandemic is having profound psychological impacts MESHD. The concerns we identified largely reflect objective, as well as subjective, aspects of the current situation. Hence, key approaches to reducing these concerns require changes to the reality of their situation, and are likely to include i) helping people optimise their health, limit risk of infection TRANS risk of infection TRANS infection MESHD, and access necessities; ii) minimising the negative experience of disease where possible, iii) providing up-to-date, accurate and consistent information, iv) improving the government and healthcare response.

    Computed Tomography Findings and Short-term follow-up with Novel Coronavirus Pneumonia HP

    Authors: Shi Qi; Hui Guo; Hua Shao; Siqin Lan; Yuanlin He; Maijudan Tiheiran; Hongjun Li

    doi:10.1101/2020.04.02.20042614 Date: 2020-04-04 Source: medRxiv

    Objective: To assess the characteristics of computed tomography (CT) features and changes in CT monitoring in patients with novel coronavirus pneumonia HP (NCP) . Methods: In this retrospective, two-center study, we reviewed the medical records of 57 patients with NCP in CT from January 21 to February 12, 2020. Cases were confirmed TRANS by the results of nucleic acid test positive, and were analyzed for demographic, clinical, and CT features. Results: Of the 57 patients, 31cases were male TRANS, and 45.6% were female TRANS. The average age TRANS was 46.5 years. Patients had fever HP (84.2%), cough HP (49.1%), weak (31.6%), muscle ache (17.5%), shortness of breath (12.3%). The distribution of abnormality was a subpleural lesions in 51 cases, with 96.5% ground-glass opacity (GGO) and 68.4% consolidation. Another observation reveals 45.6% fibrosis, 33.3% lymph node enlargement, 21.1% pleural thickening HP, 17.5% small nodule, 7.0% white lung, 5.3% emphysema HP, and 3.5% bronchiectasis HP. Importantly, the group of men had more septal thickening and air trapping than the female TRANS group (p < 0.05); Compared with the younger, the elderly TRANS had higher of subpleural lesion, interlobular septal thickening and pleural HP thickening (p < 0.05). In the first monitoring, there were 37.3% improvement, 60.8% progress. In the second monitoring, there were 55% improvement, 35% progress. The improvement rate during the third follow-up visit was 100%. Conclusions: CT features and CT dynamic observation play a vital role in the diagnosis and treatment with NCP. It is conducive to early diagnosis, deepen the knowledge of NCP and accumulate experience.

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MeSH Disease
Human Phenotype

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