Corpus overview


MeSH Disease

Human Phenotype


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    Sleep quality and mental health of medical workers during the coronavirus disease 2019 pandemic

    Authors: Yahua Zheng; Lili Wang; Lingfei Feng; Lingxiao Ye; Aiping Zhang; Rui Fan

    doi:10.21203/ Date: 2020-09-20 Source: ResearchSquare

    Purpose To assess the sleep quality, mental health status and associated factors among medical workers during the coronavirus disease 2019 (COVID-19) pandemic. Methods A cross-sectional study was conducted and medical workers in Ningbo, China were recruited. Sleep quality was evaluated by Pittsburgh Sleep Quality Index (PSQI). Mental health status was evaluated by Symptom Checklist 90(SCL-90). Logistic regression and generalized multi-factor dimensionality reduction (GMDR) analysis were utilized to explore the risk factors and their interactions on sleep quality and mental health status. Results 207 participants were surveyed, 34.3% were found with poor sleep quality (total PSQI score > 10), mainly manifested as sleep disturbance HP sleep disturbance MESHD (92.8%). 27.05% were found with mental symptoms (Global severity index > 1.5), mainly manifested as obsessive-compulsive MESHD (25.6%). Multivariate logistic analysis showed male TRANS (OR = 3.886, 95%CI = 1.061-14.239, P = 0.040), working years >15 years (OR = 4.505, 95%CI = 1.561-12.998, P = 0.005), nurse (OR = 5.642, 95%CI = 1.347-23.632, P = 0.018), more night shifts (OR = 3.098, 95%CI = 1.308-7.336, P = 0.010), supporting Wuhan (OR = 3.413, 95%CI = 1.120-10.395, P = 0.031) were associated with poor sleep quality. GMDR analysis showed there was a two-factor interaction between working years and working shifts (P = 0.0107). No significant factors and interactions were found associated with mental symptoms. Conclusions About one-third of medical workers suffered from sleep and mental problems during the COVID-19 pandemic in the current study. Interventions for sleep MESHD and mental problems among medical workers were needed based on related factors.

    Sleep Disturbances HP Disturbances, Anxiety MESHD Anxiety HP, and Burnout during the COVID-19 Pandemic: a nationwide cross-sectional study in Brazilian Healthcare Professionals.

    Authors: Luciano Drager; Daniela Pachito; Claudia Moreno; Almir Tavares Jr.; Silvia G. Conway; Marcia Assis; Danilo A. Sguillar; Gustavo A. Moreira; Andrea Bacelar; Pedro R. Genta; Samantha K Davis; Helen E Kent; Francesca L Mordant; Timothy E Schlub; David L Gordon; David S Khoury; Kanta Subbarao; Deborah Cromer; Tom P Gordon; Amy W Chung; Miles P Davenport; Stephen J Kent

    doi:10.1101/2020.09.08.20190603 Date: 2020-09-10 Source: medRxiv

    Study objectives: To evaluate the impact of COVID-19 pandemic on sleep, anxiety HP anxiety MESHD, and Burnout in healthcare professionals. Methods: A survey was distributed using social media and organizational emails to Brazilian active healthcare professionals during the COVID-19 outbreak. We explored potential associated factors including age TRANS, gender TRANS, occupation, workplace, work hours, income, previous infection MESHD with COVID-19, recent/current contact with COVID-19 patients, regional number of incident deaths due to COVID-19, anxiety HP anxiety MESHD, and burnout. We evaluated new-onset or previous insomnia HP insomnia MESHD worsening (primary outcome), sleep quality, and duration (secondary outcomes). Results: A total of 4,384 health professionals from all regions of the country were included in the analysis (mean age TRANS: 44{+/-}12 years, 76% females TRANS, 53.8% physicians). Overall, 55.7% were assisting patients with COVID-19, and 9.2% had a previous COVID-19 infection MESHD. New-onset insomnia HP insomnia MESHD symptoms or previous insomnia HP insomnia MESHD worsening occurred in 41.4% of respondents in parallel to 13% (n=572) new pharmacological treatments for insomnia HP insomnia MESHD. Prevalent anxiety HP anxiety MESHD and burnout during the pandemic were observed in 44.2% and 21% of participants, respectively. Multivariate analyses showed that females TRANS (OR:1.756; 95% CI 1.487-2.075), weight change (decrease: OR:1.852; 95% CI 1.531-2.240; increase: OR:1.542; 95% CI 1.323-1.799), prevalent anxiety HP anxiety MESHD (OR:3.209; 95% CI 2.796-3.684), new-onset burnout (OR:1.986; 95% CI 1.677-2.352), family income reduction >30% (OR:1.366; 95% CI 1.140-1.636) and assisting patients with COVID-19 (OR:1.293; 95% CI 1.104-1.514) were independently associated with new-onset or worsening of previous insomnia HP insomnia MESHD. Conclusions: We observed a huge burden of insomnia HP insomnia MESHD in healthcare professionals during the COVID-19 pandemic. In this scenario, dedicated approaches for sleep health are highly desirable.

    The inevitability of Covid-19 related distress among healthcare workers: findings from a low caseload country under lockdown

    Authors: Feras Ibrahim Hawari; Nour A Obeidat; Yasmeen I Dodin; Asma S Albtoosh; Rasha M Manasrah; Ibrahim O Alaqeel; Asem H Mansour

    doi:10.1101/2020.06.14.20130724 Date: 2020-06-16 Source: medRxiv

    Objectives: To characterize psychological distress MESHD and factors associated with distress in healthcare practitioners working during a stringent lockdown in a country (Jordan) with one of the lowest incidence rates of Covid-19 globally. Methods: A cross-sectional online survey sent to physicians, nurses and technicians, and pharmacists working in various hospitals and community pharmacies. Demographic, professional and psychological characteristics (distress using Kessler-6 questionnaire, anxiety HP anxiety MESHD, depression MESHD, burnout, sleep issues, exhaustion) were measured as were potential sources of fear. Descriptive and multivariable statistics were performed using level of distress as the key outcome. Results: We surveyed 1,006 practitioners (55.3% females TRANS). Approximately 63%, 13%, 17% and 7% were nurses/technicians, physicians, pharmacists, and other nonmedical personnel (respectively). 32% suffered from high distress while 20% suffered from severe distress. Exhaustion, anxiety HP anxiety MESHD, depression MESHD, and sleep disturbances HP sleep disturbances MESHD were reported (in past seven days) by approximately 34%, 34%, 19%, and 29% of subjects (respectively). Being older or male TRANS, perception of effective protective institutional measures, and being satisfied at work, were significantly associated with lower distress. Conversely, suffering burnout; reporting sleep-related functional problems; exhaustion; being a pharmacist (relative to a physician) and working in a cancer MESHD center; harboring fear about virus spreading; fear that the virus threatened life; fear of alienation from family/ friends TRANS; and fear of workload increases, were significantly associated with higher distress. Conclusion: Despite low caseloads, Jordanian practitioners still experienced high levels of distress. Identified demographic, professional and psychological factors influencing distress should inform interventions to improve medical professional resilience and distress likelihood, regardless of the variable Covid-19 situation.

    Does Sars-Cov-2 threaten our dreams? Effect of Quarantine on Sleep Quality and Body Mass Index

    Authors: Luigi Barrea; Gabriella Pugliese; Lydia Framondi; Rossana Di Matteo; Daniela Laudisio; Silvia Savastano; Annamaria Colao; Giovanna Muscogiuri

    doi:10.21203/ Date: 2020-06-02 Source: ResearchSquare

    Background: COVID 19- related quarantine led to a sudden and radical lifestyle changes, in particular in eating habits. Objectives of the study were to investigate the effect of quarantine on sleep quality (SQ) and body mass index (BMI), and if change in SQ was related to working modalities.Materials: We enrolled 121 adults TRANS ( age TRANS 44.9±13.3 years and 35.5% males TRANS). Anthropometric parameters, working modalities and physical activity were studied. Sleep quality was evaluated by the Pittsburgh Sleep Quality Index (PSQI) questionnaire. At baseline, the enrolled subjects were assessed in outpatient clinic and after 40 days of quarantine/lockdown by phone interview. Results: Overall, 49.6% of the subjects were good sleepers (PSQI < 5) at the baseline and significantly decreased after quarantine (p<0.001). In detail, sleep onset latency (p<0.001), sleep efficiency (p=0.03), sleep disturbances HP (p<0.001), and daytime dysfunction MESHD (p<0.001) significantly worsened. There was also a significant increase in BMI values in normal weight (p=0.023), in subjects grade I (p=0.027) and II obesity MESHD obesity HP (p=0.020). In all cohort, physical activity was significantly decreased (p=0.004). However, analyzing the data according gender TRANS difference, males TRANS significantly decreased physical activity as well as females TRANS in which there was only a trend without reaching statistical significance (53.5% vs 25.6%; p=0.015 and 50.0% vs 35.9%, p=0.106; in males TRANS and females TRANS, respectively). In addition, smart working activity resulted in a significant worsening of SQ, particularly in males TRANS (p<0.001). Conclusions: Quarantine was associated to a worsening of SQ, particularly in males TRANS doing smart working, and to an increase in BMI values. 

    Anxiety HP Anxiety MESHD, depression MESHD, attitudes, and internet addiction during the initial phase of the 2019 coronavirus disease MESHD (COVID-19) epidemic: A cross-sectional study in Mexico.

    Authors: Bryan Adrian Garcia-Priego; Arturo Triana-Romero; Samanta Mayanini Pinto-Galvez; Cristina Duran-Ramos; Omar Salas-Nolasco; Marisol Manriquez Reyes; Antonio Ramos de la Medina; Jose Maria Remes Troche

    doi:10.1101/2020.05.10.20095844 Date: 2020-05-15 Source: medRxiv

    Abstract Objectives: To describe the prevalence SERO and distribution of anxiety HP anxiety MESHD and depression MESHD among Mexican population, and to examine its association with internet addiction during the COVID-19 outbreak. Design: A web-based cross-sectional study. Setting: General population in Mexico. Participants: 561 subjects were recruited (71% female TRANS, mean age TRANS of was 30.7 {+/-} 10.6 years). Interventions: An online survey to assess personal attitudes and perceptions towards COVID-19, sleep-disorders MESHD related, the Mexican version of the Hospital Anxiety HP Anxiety MESHD and Depression Scale (HADS) and the Internet Addiction Test (IAT) was applied. Primary and secondary outcome measures: Prevalence SERO of anxiety HP anxiety MESHD, depression MESHD, internet addiction and sleep disorders MESHD and associated factors. Also, prevalence SERO for anxiety HP anxiety MESHD and depression MESHD were compared to an historic control group. Results: During the initial phase of the COVID-19 pandemic the prevalence SERO for anxiety HP anxiety MESHD and depression MESHD was 50% (95% CI, 45.6% to 54.1%) and 27.6%, (95% CI 23.8% to 31.4%), respectively. We found a 51% (33% to 50%) increase in anxiety HP anxiety MESHD and up to 86% increase in depression MESHD uring the initial weeks of the lock-down compared to the control group. According to the IAT questionnaire, 62.7% (95% CI 58.6% to 68.8%) of our population had some degree of internet addiction. Odds ratio for development of anxiety HP anxiety MESHD symptoms was 2.02 (95% CI1.56-2.1, p=0.0001) and for depression MESHD was 2.15 (95% CI 1.59-2.9, p=0.0001). In the multivariate analysis, younger age TRANS (p=0.006), sleep problems (p=0.000), and internet addiction ( p=0.000) were associated with anxiety HP anxiety MESHD and depression. Conclusions: Our study provides valuable information on the psychological impact that the COVID-19 pandemic has had on the Mexican population. As in other parts of the globe, in Mexico, fear of SARS-CoV-2 infection MESHD has had devastating consequences on mental health, such as anxiety HP anxiety MESHD, depression MESHD and sleeping disturbances HP sleeping disturbances MESHD. Internet abuse and the consequent overexposure to rapidly spreading misinformation (infodemia) are associated to anxiety HP anxiety MESHD and depression.

    The German COVID-19 Survey on Mental Health: Primary Results

    Authors: Stefanie Jung; Jonas Kneer; Tillmann Krueger

    doi:10.1101/2020.05.06.20090340 Date: 2020-05-12 Source: medRxiv

    Abstract First cases of COVID-19 were reported in Wuhan, China in early December 2019. Preliminary data from China indicated a substantial impact on mental health by the pandemic and its associated lockdown measures. Such measures are unprecedented for the majority of people and may affect their lives tremendously. The current survey was developed to assess mental health in response to the lockdown in Germany. Methods We conducted a web-based self-report survey including various aspects of mental health (e.g. PHQ-D, PHQ-4, WHO-5 and comparative questions on a 5-point Likert scale concerning sleep, irritability HP irritability MESHD & interpersonal violence). First wave data were taken during the height of lockdown measures in Germany from 1 April to 15 April 2020. Results A total of 3,545 volunteers took part in this cross-sectional survey. Mean age TRANS was 40.36 years (SD = 11.70; 83.1% female TRANS, 15.2% male TRANS). Acute or chronic disease MESHD was reported by 36.7% (physical) and 24.7% (mental) of subjects. Participants scored mild severity distress in the PHQ stress module. Depression MESHD and anxiety HP anxiety MESHD as assessed by PHQ-4 was significantly higher than in reference samples. The mean well-being score (WHO-5) was 50.7, thus pointing towards possible signs of depression MESHD. Furthermore, we found significant gender TRANS differences for anxiety HP anxiety MESHD and depression with women showing higher levels. 45.3% of participants reported worsened sleep, increased levels of irritation, anger and aggression MESHD compared to pre-pandemic times. Most importantly, 5% of all participants reported experiencing interpersonal violence (IPV). Discussion This is one of the first and largest surveys on mental health during the COVID-19 pandemic in a European society reflecting a relatively well educated and financially secure sample. Yet, there is evidence for a substantial mental burden with increased levels of stress, anxiety HP anxiety MESHD, depressive symptoms MESHD, sleep disturbance HP sleep disturbance MESHD and irritability HP. Most importantly and also most concerning is the finding of a one-month prevalence SERO of 5% IPV. We think it is of vital importance to continuously monitor the mental health of the general public during this pandemic and its aftermath and to carefully screen for IPV and its risk factors such as stress, sleep problems and anger.

    Multimodal Physical Therapy Approach on Depression MESHD, Anxiety HP Anxiety MESHD, Stress and Quality of Life in Subject with Home Quarantine for COVID-19 Pandemic Attack- A Case Study From India

    Authors: Ramesh Patra; Biswajit Kanungo

    doi:10.21203/ Date: 2020-05-12 Source: ResearchSquare

    Purpose: The main purpose of our study was to evaluate the effectiveness of   multidisciplinary physiotherapy approach on depression MESHD, anxiety HP anxiety MESHD, stress and quality of life during lockdown periods for the COVID-19 pandemic attack. Method: The patient was 56 years female TRANS complaining with restlessness HP restlessness MESHD and sleep disturbances HP at night in an outpatient department, Jalandhar Physiotherapy, India. She was a known case of hypertension HP hypertension MESHD and grade-2 bilateral knee osteoarthritis HP osteoarthritis MESHD. Her level of depression MESHD, anxiety HP anxiety MESHD and stress was evaluated through DASS-21 ( Depression Anxiety Stress MESHD Anxiety HP Stress Scale) questionnaire. Short Form of health related questionnaire (SF-36) was used for the assessment of quality of life. Emotional liberation breathing technique and multimodal physical therapy approaches were used to treat the patient for 2 weeks of periods 3 sessions per week. Results: After four weeks of follow up the patient was presented with significant improvement in all the parameters depression MESHD, anxiety HP anxiety MESHD, stress and quality of life (physical functioning, role of limitation-physical health, role of limitation-emotional health, energy,  emotional wellbeing, Body pain HP pain MESHD and general health). These outcomes were reduced the use of analgesics and sedative drugs.  Conclusion: Therefore, the outcomes of this case study concluded that multidimensional therapeutic approach is a beneficial approach to manage depression MESHD, anxiety HP anxiety MESHD, quality of life, and sleep quality.

    The Evaluation of Sleep Disturbances HP for Chinese Frontline Medical Workers Under the Outbreak of COVID-19


    doi:10.1101/2020.03.06.20031278 Date: 2020-03-08 Source: medRxiv

    Background The outbreak of coronavirus disease MESHD 2019 in China remains to be a serious challenge for frontline medical workers (fMW). They are under high risk of being infected and high mental stress, which may lead to sleep disturbances HP sleep disturbances MESHD, anxiety HP anxiety MESHD, and depression MESHD. Methods We conducted a cross-sectional study to evaluate sleep disturbances HP of fMW and made a comparison with non-fMW. The medical workers from multiple hospitals in Hubei Province, China, were volunteered to participate. An online questionnaire, including Pittsburgh Sleep Quality Index (PSQI), Athens Insomnia MESHD Insomnia HP Scale (AIS), and Visual Analogue Scale (VAS), was used to evaluate sleep disturbances HP sleep disturbances MESHD and mental status of fMW. Sleep disturbances HP were defined as PSQI>7 points or/and AIS>6 points. We compared the scores of PSQI, AIS, anxiety HP anxiety MESHD and depression VAS, and prevalence SERO of sleep disturbances HP between fMW and non-fMW. Subgroup analysis for different gender TRANS in fMW was conducted. Findings A total of 1306 subjects (including 801 fMW and 505 non-fMW) were enrolled. Compared to non-fMW, fMW had significantly higher scores of PSQI (p<0.0001), AIS (p<0.0001), anxiety HP anxiety MESHD (p<0.0001) and depression MESHD (p=0.0010), and higher prevalence SERO of sleep disturbances HP sleep disturbances MESHD with PSQI > 7 points (p<0.0001) and AIS > 6 points (p<0.0001). In subgroup analysis, compared to male TRANS fMW, female TRANS fMW had significantly higher scores of PSQI (p=0.022) and higher prevalence SERO of sleep disturbances HP sleep disturbances MESHD with PSQI > 7 points (p<0.0001). Interpretation fMW had higher prevalence SERO of sleep disturbances HP sleep disturbances MESHD and worse sleep quality than non-fMW. Female TRANS fMW were more vulnerable to having sleep disturbances HP sleep disturbances MESHD than male TRANS fMW. Funding None.

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MeSH Disease
Human Phenotype

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