Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Echocardiographic patterns in critically ill COVID-19 patients.

    Authors: Antoine Vieillard-Baron; Cyril Charron; Ségolène Tran; Matthieu Godement; Xavier Repessé; Pierre-Alexandre Haruel; Amélie Prigent; Samuel Castro; Lola Girodias; Emilie Charbit; Foucault Isnard; Mohamed Saleh; Koceila Bouferrache; Bernard Page; Romain Jouffroy; Guillaume Geri

    doi:10.21203/rs.3.rs-52431/v1 Date: 2020-08-01 Source: ResearchSquare

    Background: Need for catecholamines is frequent in COVID-19 patients, but the main echocardiographic patterns are unknown. The objective was to report the main echo patterns in critically-ill COVID-19 patients. Methods: Observational and descriptive study in consecutive COVID-19 patients admitted to the ICU between March 12 and May 8, 2020. Systematic critical care echocardiography (CCE) was performed and retrospectively analyzed off-line. Echo values are reported in the overall population and in patients who required catecholamine infusion during the first 2 days following admission (D1-2) or afterwards until day 7 (D3-7). Results: Of the 79 patients (78% male TRANS; median age TRANS 63 [56-71]; body mass index 29 [26-30]) included, 90% had at least 1 comorbidity. PaO2/FiO2 at admission was 85 [67-162] mmHg. 53% of patients were mechanically ventilated. ICU length of stay was 9 [5-16] days and mortality 34%. 134 echocardiographic studies were performed during the first week in 65 patients. Pulmonary artery acceleration time was decreased (77 [65-97] ms), suggesting pulmonary hypertension MESHD hypertension HP. All 39 patients (49%) who required catecholamine infusion underwent CCE and 25.6% had left ventricular ( LV MESHD) systolic dysfunction MESHD, 28.2% acute cor pulmonale HP (ACP), 7.7% hypovolemia HP hypovolemia MESHD, and 38.5% vasoplegia MESHD. Modification of echo patterns was observed at D3-7, with less LV systolic dysfunction MESHD and more ACP, which was the most frequent pattern. Computed tomography pulmonary angiography in 6 patients with ACP indicated intrapulmonary thrombus MESHD in 4. Conclusion: Different echocardiographic patterns were observed during the first week following ICU admission in COVID-19 patients. ACP was frequent and often related to thrombus in the pulmonary circulation. 

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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