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MeSH Disease

Human Phenotype

Transmission

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    First Case of COVID-19 Complicated with Fulminant Myocarditis MESHD Myocarditis HP: A case Report and Insights

    Authors: Jia Hui Zeng; Ying-Xia Liu; Jing Yuan; Fu-Xiang Wang; Wei-Bo Wu; Jin-Xiu Li; Li-Fei Wang; Hong Gao; Yao Wang; Chang-Feng Dong; Yi-Jun Li; Xiao-Juan Xie; Cheng Feng; Lei Liu

    id:202003.0180/v2 Date: 2020-04-06 Source: Preprints.org

    Background: Coronavirus Disease MESHD 2019 (COVID-19) has been demonstrated to be the cause of pneumonia HP pneumonia MESHD. Nevertheless, it has not been reported as the cause of acute myocarditis HP myocarditis MESHD or fulminant myocarditis HP myocarditis MESHD. Case presentation: A 63-year-old male TRANS was admitted with pneumonia HP pneumonia MESHD and cardiac symptoms MESHD. He was genetically confirmed as having COVID-19 according to sputum testing on the day of admission. He also had elevated troponin I (Trop I) level (up to 11.37 g/L) and diffuse myocardial dyskinesia MESHD dyskinesia HP along with a decreased left ventricular ejection fraction (LVEF) on echocardiography. The highest level of interleukin-6 was 272.40 pg/ml. Bedside chest radiographs showed typical ground-glass changes indicative of viral pneumonia MESHD pneumonia HP. Laboratory test results for viruses that cause myocarditis HP myocarditis MESHD were all negative. The patient conformed to the diagnostic criteria of the Chinese expert consensus statement for fulminant myocarditis HP myocarditis MESHD. After receiving antiviral therapy and mechanical life support, Trop I was reduced to 0.10 g/L, and interleukin-6 was reduced to 7.63 pg/ml. Moreover, the LVEF of the patient gradually recovered to 68%. The patient died of aggravation of secondary infection on the 33rd day of hospitalization. Conclusion: COVID-19 patients may develop severe cardiac complications MESHD such as myocarditis HP myocarditis MESHD and heart failure MESHD. This is the first report of COVID-19 complicated with fulminant myocarditis HP myocarditis MESHD. The mechanism of cardiac pathology caused by COVID-19 needs further study.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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