Corpus overview


Overview

MeSH Disease

Human Phenotype

Fever (1)

Cough (1)

Fatigue (1)

Myalgia (1)

Headache (1)


Transmission

fomite (1)

gender (1)


Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Olfactory and Gustatory Dysfunctions in Patients With COVID-19 in Wuhan, China

    Authors: Li Zou; Ting Yu; Yangyang Zhang; Lijun Dai; Zhaohui Zhang; Zhentao Zhang

    doi:10.21203/rs.3.rs-28370/v1 Date: 2020-05-11 Source: ResearchSquare

    Background: The coronavirus disease MESHD 2019 (COVID-19) caused by SARS-CoV-2 isspreading all over the world.The main symptoms of COVID-19 include fever HP fever MESHD, cough HP cough MESHD, fatigue HP, and myalgia HP myalgia MESHD. However, there are few reports onolfactoryand gustatory dysfunctions MESHD in patients with COVID-19.Objective: To investigate the incidence of olfactory and gustatory dysfunctions MESHD in patients with confirmed COVID-19 infection MESHD, in Wuhan, China.Methods:In this retrospective study,we collected 81 confirmed cases TRANS of COVID-19 from the Renmin Hospital of Wuhan University, from February 2020 to March 2020, and analyzed the demographic characteristics, clinical manifestations (including olfactory and  gustatory dysfunctions MESHD), laboratory findings,and comorbidities.Results: A total of 81 confirmed COVID-19 patients were enrolledin this study (38 males TRANS). The most prevalent symptoms include cough HP cough MESHD, myalgia HP myalgia MESHD, and loss of appetite. On admission, 25 (30.9%) of all patients reported either olfactory dysfunction MESHD ( OD MESHD) or gustatory dysfunction MESHD ( GD MESHD), and 7 (8.6%) reported both OD MESHD and GD MESHD. 13.6% and 25.9% of allpatients reported OD MESHD and GD MESHD, respectively. OD MESHD and GD MESHD were not associated with disease severity. Pearson correlation analysisidentified some factors are positively correlated with OD MESHD and GD MESHD, including headache HP headache MESHD or dizziness (r = 0.342, P = 0.002), dark urine HP (r = 0.256, P = 0.021), IgM titer (r = 0.305, P = 0.01), and diabetes MESHD (r = 0.275, P = 0.013). In 81.8% of the cases with OD MESHD and 28.6% of the cases with GD MESHD, the symptomslasted for at least 1 month after discharge.3.6% of inpatients without OD MESHD developed OD MESHD after discharge.Conclusion: OD MESHD and GDare common in COVID-19.These symptoms appear early during thecourse of disease, and may last for at least 1 month.The incidence of OD MESHD and GDisrelated to neurological manifestations, diabetics MESHD, and IgM titers.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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