Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Epidemiological and clinical characteristics of the early phase of the COVID-19 epidemic in Brazil

    Authors: William Marciel de Souza; Lewis Fletcher Buss; Darlan da Silva Candido; Jean Paul Carrera; Sabrina Li; Alexander Zarebski; Maria Vincenti-Gonzalez; Janey Messina; Flavia Cristina da Silva Sales; Pamela dos Santos Andrade; Carlos A Prete Jr.; Vitor Heloiz Nascimento; Fabio Ghilardi; Rafael Henrique Moraes Pereira; Andreza Aruska de Souza Santos; Leandro Abade; Bernardo Gutierrez; Moritz U. G. Kraemer; Renato Santana Aguiar; Neal Alexander; Philippe Mayaud; Oliver J Brady; Izabel Oliva Marcilio de Souza; Nelson Gouveia; Guangdi Li; Adriana Tami; Silvano Barbosa Oliveira; Victor Bertollo Gomes Porto; Fabiana Ganem; Walquiria Ferreira Almeida; Francieli Fontana Sutile Tardetti Fantinato; Eduardo Marques Macario; Wanderson Kleber Oliveira; Oliver Pybus; Chieh-Hsi Wu; Julio Croda; Ester Cerdeira Sabino; Nuno R. Faria

    doi:10.1101/2020.04.25.20077396 Date: 2020-04-29 Source: medRxiv

    Background: The first case of COVID-19 was detected in Brazil on February 25, 2020. We report the epidemiological, demographic, and clinical findings for confirmed COVID-19 cases during the first month of the epidemic in Brazil. Methods: Individual-level and aggregated COVID-19 data were analysed to investigate demographic profiles, socioeconomic drivers and age TRANS-sex structure of COVID-19 tested cases. Basic reproduction numbers TRANS ( R0 TRANS) were investigated for Sao Paulo and Rio de Janeiro. Multivariate logistic regression analyses were used to identify symptoms associated with confirmed cases TRANS and risk factors associated with hospitalization. Laboratory diagnosis for eight respiratory viruses were obtained for 2,429 cases. Findings: By March 25, 1,468 confirmed cases TRANS were notified in Brazil, of whom 10% (147 of 1,468) were hospitalised. Of the cases acquired locally (77.8%), two thirds (66.9% of 5,746) were confirmed in private laboratories. Overall, positive association between higher per capita income and COVID-19 diagnosis was identified. The median age TRANS of detected cases was 39 years (IQR 30-53). The median R0 TRANS was 2.9 for Sao Paulo and Rio de Janeiro. Cardiovascular disease MESHD/ hypertension HP hypertension MESHD were associated with hospitalization. Co-circulation of six respiratory viruses, including influenza A and B and human rhinovirus was detected in low levels. Interpretation: Socioeconomic disparity determines access to SARS-CoV-2 testing in Brazil. The lower median age TRANS of infection MESHD and hospitalization compared to other countries is expected due to a younger population structure. Enhanced surveillance of respiratory pathogens across socioeconomic statuses is essential to better understand and halt SARS-CoV-2 transmission TRANS.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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