Corpus overview


MeSH Disease

Human Phenotype


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    The impact of COVID-19 on the lives and mental health of Australian adolescents

    Authors: Sophie Li; Joanne Beames; Jill Newby; Kate Maston; Helen Christensen; Aliza Werner-Seidler; Marina Pifano; Teresa Varela; Enio Garcia; Alicia Lawrynowicz; Osvaldo Uez; Irene Pagano; Anastasija Caica; Mikus Gavars; Dmitrijs Perminovs; Jelena Storozenko; Oksana Savicka; Elina Dimina; Uga Dumpis; Janis Klovins

    doi:10.1101/2020.09.07.20190124 Date: 2020-09-09 Source: medRxiv

    Objective: There has been significant disruption to the lives and mental health of adolescents during the COVID-19 pandemic, but the exact nature of the effects is not known. The purpose of this study was to assess the psychological and lifestyle impact of the pandemic on Australian adolescents, using an online survey, administered during and after the peak of the outbreak (June-July 2020). Method: Self-report surveys were administered online to a sample of 760 Australian adolescents aged TRANS 12-18 years old. Surveys assessed worry about contracting COVID-19, behavioral change in response to the pandemic, impact on education, peer and family relationships, lifestyle factors including exercise, technology use and sleep, as well as mental health outcomes including psychological distress, loneliness, health anxiety HP anxiety MESHD and wellbeing. Results: Overall, young people expressed significant concern and worry about contracting the virus, and most (>85%) engaged in behaviors to reduce the risk of transmission TRANS. Three quarters of the sample reported a worsening of their mental health since the pandemic began, with negative impacts reported by most respondents on learning, friendships and family relationships. More than 40% of young people reported a decrease in exercise and 70% reported an increase in technology use since the outbreak. There were high levels of uncertainty about the future reported by respondents, and their scores on validated measures indicated higher levels of sleep disturbance HP sleep disturbance MESHD, psychological distress MESHD and health anxiety HP anxiety MESHD, and lower levels of wellbeing, relative to normative samples. Reponses on the Kessler Psychological Distress Scale indicated that 48.3% of the sample were experiencing distress consistent with a probable mental illness MESHD, which is much higher than pre-pandemic prevalence SERO rates. Effects on mental health were worse among those who reported a previous diagnosis of depression MESHD and/or anxiety HP anxiety MESHD relative to those without a history of depression MESHD and/or anxiety HP anxiety MESHD. Conclusion: These results indicate high levels of disruption and psychological distress experienced by adolescents during the current COVID-19 pandemic. Adolescents are already vulnerable to the onset of mental illness at this developmental stage, and the current research underscores the need to find rapid and accessible ways to support adolescent mental health during times of crisis. There is a need for longitudinal research to evaluate the enduring effects of the pandemic on adolescents.

    The Impact of Psychology Interventions on Changing Mental Health Status and Sleep Quality in University Students during the COVID-19 Pandemic

    Authors: Jing Xiao; Yu Jiang; Yu Zhang; Xinyi Gu; Wenjing Ma; Bo Zhuang; Ziqi Zhou; Lingli Sang; Yitian Luo; Yulong Lian; Sarah Connelly; Elena Sheldon; Jamie Hall; Emma Young; Andrew Bentley; Kirsty Challen; Chris Fitzsimmons; Tim Harris; Fiona Lecky; Andrew Lee; Ian Maconochie; Darren Walter; Dilek Telci; Fikrettin Sahin; Koray Yalcin; Ercument Ovali

    doi:10.1101/2020.09.01.20186411 Date: 2020-09-03 Source: medRxiv

    Abstract Objective We evaluated the change in mental health and sleep quality of college students at four time periods. Methods Mental health status and sleep quality were using the Pittsburgh Sleep Quality Index (PSQI) and Symptom Checklist-90-Revised (SCL-90-R) questionnaire across four time periods. Psychology interventions were carried out from the third period. Results Students in the third period had higher PSQI total scores [mean (SD), 6.01 (3.27)] than those in the first period [5.60 (3.11)], second period [4.17 (2.10)] and fourth period [4.09 (2.80)]. After adjustment for covariates there was a decline of 1.89 points in the PSQI in the fourth period compared with the highest period. The SCL-90-R scores were highest in the second period [121.19 (47.83)], and were higher than the scores in the first [107.60 (52.21)] and second period [107.79 (27.20)] and lowest in the fourth period [97.82 (17.12)]. The decline in scores was 23.38 points after adjustment for covariates. The prevalence SERO of psychological distress MESHD and sleep disturbances HP respectively decreased from 28.6% to 11.7% and from 10.4% to 2.6% comparing to the highest period. Sleep quality showed a significant positive correlation with mental health status. Conclusions The pattern of change in mental health status was different to that of sleep quality. The implementation of comprehensive psychology intervention may improve mental health and sleep quality. These findings may inform public health policy during the reopening of schools in other regions.

    Anxiety HP Anxiety MESHD, depression MESHD, attitudes, and internet addiction during the initial phase of the 2019 coronavirus disease MESHD (COVID-19) epidemic: A cross-sectional study in Mexico.

    Authors: Bryan Adrian Garcia-Priego; Arturo Triana-Romero; Samanta Mayanini Pinto-Galvez; Cristina Duran-Ramos; Omar Salas-Nolasco; Marisol Manriquez Reyes; Antonio Ramos de la Medina; Jose Maria Remes Troche

    doi:10.1101/2020.05.10.20095844 Date: 2020-05-15 Source: medRxiv

    Abstract Objectives: To describe the prevalence SERO and distribution of anxiety HP anxiety MESHD and depression MESHD among Mexican population, and to examine its association with internet addiction during the COVID-19 outbreak. Design: A web-based cross-sectional study. Setting: General population in Mexico. Participants: 561 subjects were recruited (71% female TRANS, mean age TRANS of was 30.7 {+/-} 10.6 years). Interventions: An online survey to assess personal attitudes and perceptions towards COVID-19, sleep-disorders MESHD related, the Mexican version of the Hospital Anxiety HP Anxiety MESHD and Depression Scale (HADS) and the Internet Addiction Test (IAT) was applied. Primary and secondary outcome measures: Prevalence SERO of anxiety HP anxiety MESHD, depression MESHD, internet addiction and sleep disorders MESHD and associated factors. Also, prevalence SERO for anxiety HP anxiety MESHD and depression MESHD were compared to an historic control group. Results: During the initial phase of the COVID-19 pandemic the prevalence SERO for anxiety HP anxiety MESHD and depression MESHD was 50% (95% CI, 45.6% to 54.1%) and 27.6%, (95% CI 23.8% to 31.4%), respectively. We found a 51% (33% to 50%) increase in anxiety HP anxiety MESHD and up to 86% increase in depression MESHD uring the initial weeks of the lock-down compared to the control group. According to the IAT questionnaire, 62.7% (95% CI 58.6% to 68.8%) of our population had some degree of internet addiction. Odds ratio for development of anxiety HP anxiety MESHD symptoms was 2.02 (95% CI1.56-2.1, p=0.0001) and for depression MESHD was 2.15 (95% CI 1.59-2.9, p=0.0001). In the multivariate analysis, younger age TRANS (p=0.006), sleep problems (p=0.000), and internet addiction ( p=0.000) were associated with anxiety HP anxiety MESHD and depression. Conclusions: Our study provides valuable information on the psychological impact that the COVID-19 pandemic has had on the Mexican population. As in other parts of the globe, in Mexico, fear of SARS-CoV-2 infection MESHD has had devastating consequences on mental health, such as anxiety HP anxiety MESHD, depression MESHD and sleeping disturbances HP sleeping disturbances MESHD. Internet abuse and the consequent overexposure to rapidly spreading misinformation (infodemia) are associated to anxiety HP anxiety MESHD and depression.

    The German COVID-19 Survey on Mental Health: Primary Results

    Authors: Stefanie Jung; Jonas Kneer; Tillmann Krueger

    doi:10.1101/2020.05.06.20090340 Date: 2020-05-12 Source: medRxiv

    Abstract First cases of COVID-19 were reported in Wuhan, China in early December 2019. Preliminary data from China indicated a substantial impact on mental health by the pandemic and its associated lockdown measures. Such measures are unprecedented for the majority of people and may affect their lives tremendously. The current survey was developed to assess mental health in response to the lockdown in Germany. Methods We conducted a web-based self-report survey including various aspects of mental health (e.g. PHQ-D, PHQ-4, WHO-5 and comparative questions on a 5-point Likert scale concerning sleep, irritability HP irritability MESHD & interpersonal violence). First wave data were taken during the height of lockdown measures in Germany from 1 April to 15 April 2020. Results A total of 3,545 volunteers took part in this cross-sectional survey. Mean age TRANS was 40.36 years (SD = 11.70; 83.1% female TRANS, 15.2% male TRANS). Acute or chronic disease MESHD was reported by 36.7% (physical) and 24.7% (mental) of subjects. Participants scored mild severity distress in the PHQ stress module. Depression MESHD and anxiety HP anxiety MESHD as assessed by PHQ-4 was significantly higher than in reference samples. The mean well-being score (WHO-5) was 50.7, thus pointing towards possible signs of depression MESHD. Furthermore, we found significant gender TRANS differences for anxiety HP anxiety MESHD and depression with women showing higher levels. 45.3% of participants reported worsened sleep, increased levels of irritation, anger and aggression MESHD compared to pre-pandemic times. Most importantly, 5% of all participants reported experiencing interpersonal violence (IPV). Discussion This is one of the first and largest surveys on mental health during the COVID-19 pandemic in a European society reflecting a relatively well educated and financially secure sample. Yet, there is evidence for a substantial mental burden with increased levels of stress, anxiety HP anxiety MESHD, depressive symptoms MESHD, sleep disturbance HP sleep disturbance MESHD and irritability HP. Most importantly and also most concerning is the finding of a one-month prevalence SERO of 5% IPV. We think it is of vital importance to continuously monitor the mental health of the general public during this pandemic and its aftermath and to carefully screen for IPV and its risk factors such as stress, sleep problems and anger.

    The Evaluation of Sleep Disturbances HP for Chinese Frontline Medical Workers Under the Outbreak of COVID-19


    doi:10.1101/2020.03.06.20031278 Date: 2020-03-08 Source: medRxiv

    Background The outbreak of coronavirus disease MESHD 2019 in China remains to be a serious challenge for frontline medical workers (fMW). They are under high risk of being infected and high mental stress, which may lead to sleep disturbances HP sleep disturbances MESHD, anxiety HP anxiety MESHD, and depression MESHD. Methods We conducted a cross-sectional study to evaluate sleep disturbances HP of fMW and made a comparison with non-fMW. The medical workers from multiple hospitals in Hubei Province, China, were volunteered to participate. An online questionnaire, including Pittsburgh Sleep Quality Index (PSQI), Athens Insomnia MESHD Insomnia HP Scale (AIS), and Visual Analogue Scale (VAS), was used to evaluate sleep disturbances HP sleep disturbances MESHD and mental status of fMW. Sleep disturbances HP were defined as PSQI>7 points or/and AIS>6 points. We compared the scores of PSQI, AIS, anxiety HP anxiety MESHD and depression VAS, and prevalence SERO of sleep disturbances HP between fMW and non-fMW. Subgroup analysis for different gender TRANS in fMW was conducted. Findings A total of 1306 subjects (including 801 fMW and 505 non-fMW) were enrolled. Compared to non-fMW, fMW had significantly higher scores of PSQI (p<0.0001), AIS (p<0.0001), anxiety HP anxiety MESHD (p<0.0001) and depression MESHD (p=0.0010), and higher prevalence SERO of sleep disturbances HP sleep disturbances MESHD with PSQI > 7 points (p<0.0001) and AIS > 6 points (p<0.0001). In subgroup analysis, compared to male TRANS fMW, female TRANS fMW had significantly higher scores of PSQI (p=0.022) and higher prevalence SERO of sleep disturbances HP sleep disturbances MESHD with PSQI > 7 points (p<0.0001). Interpretation fMW had higher prevalence SERO of sleep disturbances HP sleep disturbances MESHD and worse sleep quality than non-fMW. Female TRANS fMW were more vulnerable to having sleep disturbances HP sleep disturbances MESHD than male TRANS fMW. Funding None.

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MeSH Disease
Human Phenotype

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