Corpus overview


Overview

MeSH Disease

Human Phenotype

Delirium (5)

Anxiety (3)

Fever (1)

Cough (1)

Fatigue (1)


Transmission

Seroprevalence
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    Prevalence SERO of Depression MESHD, Anxiety HP Anxiety MESHD, Delirium HP, and Post- traumatic Stress Disorder MESHD Among COVID-19 Patients: Protocol for a Living Systematic Review

    Authors: Jiyuan Shi; Liang Zhao; Yuanyuan Li; Meili Yan; Niu Mingming; Yamin Chen; Ziwei Song; Ya Gao; Ruixing Zhang; Jinhui Tian

    doi:10.21203/rs.3.rs-62315/v1 Date: 2020-08-19 Source: ResearchSquare

    BackgroundPrevious studies on the impact of COVID-19 on the mental health of the patients has been limited by the lack of relevant data. With the rapid and sustained growth of the publications on COVID-19 research, we will perform a living systematic review (LSR) to provide comprehensive and continuously updated data to explore the prevalence SERO of depression MESHD, anxiety HP anxiety MESHD, delirium HP delirium MESHD, and post- traumatic stress disorder MESHD ( PTSD MESHD) among COVID-19 patients.MethodsWe will perform a comprehensive search of the following databases: Cochrane library, PubMed, Web of Science, Embase, and Chinese Biomedicine Literature to identify relevant studies. We will utilize different tools to examine the bias risks (quality) regarding studies of varying design types, such as the Newcastle-Ottawa Scale (NOS) for cohort and case-control studies, etc. Study inclusion, data extraction, and risk of bias assessments will be performed independently by two reviewers. The literature searches would be updated every three months. We will perform meta-analysis if any new eligible studies or data are obtained and resubmit an updated systematic review if any change in outcomes and heterogeneity is determined after the addition of the new studies. DiscussionThis LSR would provide an in-depth and up-to-date summary of the psychological impact of COVID-19 diagnosis and treatment on the patients. Systematic review registrationPROSPERO CRD42020196610 

    Prevalence SERO of Depression MESHD, Anxiety HP Anxiety MESHD, Delirium HP, and Post- Traumatic Stress Disorder MESHD Among COVID-19 Patients: Protocol for A Living Systematic Review

    Authors: Jiyuan Shi; Yuanyuan Li; Liang Zhao; Meili Yan; MingMing Niu; Yamin Chen; Ziwei Song; Gao Ya; Jinhui Tian

    doi:10.21203/rs.3.rs-48077/v1 Date: 2020-07-23 Source: ResearchSquare

    BackgroundPrevious studies on the impact of COVID-19 on the mental health of the patients has been limited by the lack of relevant data. With the rapid and sustained growth of the publications on COVID-19 research, we will perform a living systematic review (LSR) to provide comprehensive and continuously updated data to explore the prevalence SERO of depression MESHD, anxiety HP anxiety MESHD, delirium HP delirium MESHD, and post- traumatic stress disorder MESHD ( PTSD MESHD) among COVID-19 patients.MethodsWe will perform a comprehensive search of the following databases: Cochrane library, PubMed, Web of Science, Embase, and Chinese Biomedicine Literature to identify relevant studies. We will utilize different tools to examine the bias risks (quality) regarding studies of varying design types, such as the revised Cochrane risk-of-bias tool (RoB 2) for randomized controlled trials (RCT), the Newcastle-Ottawa Scale (NOS) for cohort and case-control studies, etc. The literature searches would be updated every month. We will perform meta-analysis if any new eligible studies or data are obtained and resubmit an updated systematic review if any change in outcomes and heterogeneity is determined after the addition of the new studies. There will be no restrictions on language or year of publication.DiscussionThis LSR would provide an in-depth and up-to-date summary of the psychological impact of COVID-19 diagnosis and treatment on the patients. Systematic review registrationPROSPERO CRD42020196610 

    Prevalence SERO of depression MESHD, anxiety HP anxiety MESHD, delirium HP delirium MESHD, and post- traumatic stress disorder MESHD among COVID-19 patients: protocol for a living systematic review

    Authors: Jiyuan Shi; Yuanyuan Li; Liang Zhao; Meili Yan; MingMing Niu; Yamin Chen; Ziwei Song; Gao Ya; Jinhui Tian

    doi:10.21203/rs.3.rs-48077/v2 Date: 2020-07-23 Source: ResearchSquare

    Background Previous studies on the impact of COVID-19 on the mental health of the patients has been limited by the lack of relevant data. With the rapid and sustained growth of the publications on COVID-19 research, we will perform a living systematic review (LSR) to provide comprehensive and continuously updated data to explore the prevalence SERO of depression MESHD, anxiety HP anxiety MESHD, delirium HP delirium MESHD, and post- traumatic stress disorder MESHD ( PTSD MESHD) among COVID-19 patients.Methods We will perform a comprehensive search of the following databases: Cochrane Library, PubMed, Web of Science, Embase, and Chinese Biomedicine Literature to identify relevant studies. We will utilize different tools to examine the bias risks (quality) regarding studies of varying design types, such as the revised Cochrane risk-of-bias tool (RoB 2) for randomized controlled trials (RCT), the Newcastle-Ottawa Scale (NOS) for cohort and case-control studies, etc. The literature searches would be updated every month. We will perform meta-analysis if any new eligible studies or data are obtained and resubmit an updated systematic review if any change in outcomes and heterogeneity is determined after the addition of the new studies. There will be no restrictions on language or year of publication.Discussion This LSR would provide an in-depth and up-to-date summary of the psychological impact of COVID-19 diagnosis and treatment on the patients. Systematic review registration PROSPERO CRD42020196610 

    Delirium HP Delirium MESHD is a presenting symptom of COVID-19 in frail, older adults TRANS: a cohort study of 322 hospitalised and 535 community-based older adults TRANS

    Authors: Maria Beatrice Zazzara; Rose S. Penfold; Amy L. Roberts; Karla Lee; Hannah Dooley; Carole H. Sudre; Carly Welch; Ruth C. E. Bowyer; Alessia Visconti; Massimo Mangino; Maxim B. Freydin; Julia S. El-Sayed Moustafa; Kerrin Small; Benjamin Murray; Marc Modat; Jonathan Wolf; Sebastien Ourselin; Finbarr C. Martin; Claire J. Steves; Mary Ni Lochlainn

    doi:10.1101/2020.06.15.20131722 Date: 2020-06-17 Source: medRxiv

    Background: Frailty, increased vulnerability to physiological stressors, is associated with adverse outcomes. COVID-19 exhibits a more severe disease course in older, co-morbid adults TRANS. Awareness of atypical presentations is critical to facilitate early identification. Objective: To assess how frailty affects presenting COVID-19 symptoms in older adults TRANS. Design: Observational cohort study of hospitalised older patients and self-report data for community-based older adults TRANS. Setting: Admissions to St Thomas' Hospital, London with laboratory-confirmed COVID-19. Community-based data for 535 older adults TRANS using the COVID Symptom Study mobile application. Subjects: Hospital cohort: patients aged TRANS 65 and over (n=322); unscheduled hospital admission between March 1st, 2020 - May 5th, 2020; COVID-19 confirmed by RT-PCR of nasopharyngeal swab. Community-based cohort: participants aged TRANS 65 and over enrolled in the COVID Symptom Study (n=535); reported test-positive for COVID-19 from March 24th (application launch)- May 8th, 2020. Methods: Multivariate logistic regression analysis performed on age TRANS-matched samples from hospital and community-based cohorts to ascertain association of frailty with symptoms of confirmed COVID-19. Results: Hospital cohort: significantly higher prevalence SERO of delirium HP delirium MESHD in the frail sample, with no difference in fever HP fever MESHD or cough HP cough MESHD. Community-based cohort: significantly higher prevalence SERO of probable delirium HP delirium MESHD in frailer, older adults TRANS, and fatigue HP fatigue MESHD and shortness of breath MESHD. Conclusions: This is the first study demonstrating higher prevalence SERO of delirium HP delirium MESHD as a COVID-19 symptom in older adults TRANS with frailty compared to other older adults TRANS. This emphasises need for systematic frailty assessment and screening for delirium HP delirium MESHD in acutely ill older patients in hospital and community settings. Clinicians should suspect COVID-19 in frail adults TRANS with delirium HP delirium MESHD.

    Functional and cognitive outcomes after COVID-19 delirium HP delirium MESHD

    Authors: Benjamin C Mcloughlin; Amy Miles; Thomas E Webb; Paul Knopp; Clodagh Eyres; Ambra Fabbri; Fiona Humphries; Daniel Davis

    doi:10.1101/2020.06.07.20115188 Date: 2020-06-09 Source: medRxiv

    Purpose To ascertain delirium HP delirium MESHD prevalence SERO and outcomes in COVID-19. Methods We conducted a point- prevalence SERO study in a cohort of COVID-19 inpatients at University College Hospital. Delirium HP Delirium MESHD was defined by DSM-IV criteria. The primary outcome was all-cause mortality at 4 weeks; secondary outcomes were physical and cognitive function. Results In 71 patients, 31 (42%) had delirium HP delirium MESHD, of which only 19 had been recognised by the clinical team. At 4 weeks, 20 (28%) had died, 26 (36%) were interviewed by telephone and 21 (30%) remained as inpatients. Physical function was substantially worse in people after delirium HP (-39 points on functional scale/166, 95% CI -92 to -21, p=0.01) (Table 2). Mean cognitive scores at follow-up were similar and delirium HP delirium MESHD was not associated with mortality in this sample. Conclusions Our findings indicate that delirium HP delirium MESHD is common, yet under-recognised. Delirium HP Delirium MESHD is associated with functional impairments in the medium-term.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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