Corpus overview


MeSH Disease

HGNC Genes

There are no HGNC terms in the subcorpus

SARS-CoV-2 proteins

There are no SARS-CoV-2 protein terms in the subcorpus


SARS-CoV-2 Proteins
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    Ocular surface manifestation of COVID-19 MESHD and tear film analysis

    Authors: Alessandro Meduri; Giovanni William Oliverio; Giuseppe Mancuso; Angela Giuffrida; Claudio Guarneri; Emmanuele Venanzi Rullo; Giuseppe Nunnari; Pasquale Aragona

    doi:10.21203/ Date: 2020-06-14 Source: ResearchSquare

    Purpose: To evaluate the ocular manifestation in patients hospitalized with coronavirus disease 2019 MESHD ( COVID-19 MESHD) and to search for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in tears.Methods: This study was conducted in 29 hospitalized patients who were admitted to the COVID center at the Policlinic Hospital of the University of Messina, Italy.All patients underwent an ophthalmologic assessment comprising a Standardized Patient Evaluation of Eye Dryness (SPEED) questionnaire, anterior segment, and the ocular surface examination of both eyes using a portable slit lamp.The Schirmer I test was performed, and the filter paper strip was used to search for the presence of SARS-CoV-2 on the ocular surface by real-time quantitative polymerase chain reaction (RT-qPCR).Results: A total of 10 patients reported ocular symptoms; in particular, four reported eye burning, three reported foreign body sensation, and three reported tearing. Moreover, seven patients presented conjunctival hyperemia and/or chemosis MESHD, eleven patients presented blepharitis MESHD signs such as lid margin hyperemia MESHD and/or telangiectasia MESHD, crusted eyelashes, and meibomian orifices alterations. Tear analysis did not reveal the presence of SARS-CoV-2.Conclusion: Ocular symptoms are common in patients with COVID-19 MESHD; although, tear analysis did not reveal the presence of SARS-CoV-2.

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MeSH Disease
HGNC Genes
SARS-CoV-2 Proteins

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