BackgroundSince Dec 2019, SARS-CoV-2 has caused about fifty thousand patients and over two thousand deaths in Wuhan, China. We reported characteristics of patients with COVID-19 MESHD
during epidemic ongoing outbreak in Wuhan.
MethodsData of COVID-19 MESHD
patients with clinical outcome in a designated hospital in Wuhan, were retrospectively collected from electronic medical records. Characteristics were compared between patients who died or recovered, and between patients with different disease severity.
ResultsBy Feb 25, 2020, 403 patients were enrolled, 100 died and 303 recovered. Most of non-survivors tended to be males, old aged, or with chronic diseases MESHD
. Duration from illness onset to admission was 9 (7-12) days. Patients with severe or critical illness MESHD
had more days from onset to admission compared to those with ordinary illness MESHD
. Lymphopenia MESHD
, anemia MESHD
, hypoproteinemia MESHD
, and abnormal serum sodium were presented in 52.6%, 54.6%, 69.8%, and 21.8% cases, respectively. Patients who died or with severe/critical illness showed increased white blood cell and neutrophil count, serum total bilirubin, creatinine, hypersensitive troponin I, D-dimer, procalcitonin, and C-reactive protein HGNC
, and decreased red blood cell, lymphocyte, platelet count, and serum albumin on admission compared to those who recovered or with ordinary illness MESHD
. Complications of acute organ injury MESHD
and secondary infection MESHD
were common in patients with COVID-19 MESHD
, especially in non-survivors.
ConclusionsMultiple homeostasis disturbances MESHD
were common in patients with severe or critical illness MESHD
at admission. Early support should be provided, especially for old men with chronic disease MESHD
, which is vital to control disease progression and reduce mortality of COVID-19 MESHD
during epidemic ongoing outbreak.