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MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak

    Authors: Seyed Hamid Reza Bagheri; Ali Mohammad Asghari; Mohammad Farhadi; Ahmad Reza Shamshiri; Ali Kabir; Seyed Kamran Kamrava; Maryam Jalessi; Alireza Mohebbi; Rafieh Alizadeh; Ali Asghar Honarmand; Babak Ghalehbaghi; Alireza Salimi

    doi:10.1101/2020.03.23.20041889 Date: 2020-03-27 Source: medRxiv

    Background Recent surge of olfactory dysfunction in patients who were referred to ENT clinics and concurrent COVID-19epidemic in Iran motivated us to evaluate anosmic/hyposmic patients to find any relation between these two events. Methods This is a cross-sectional study with an online checklist on voluntary cases in all provinces of Iran between the 12th and 17th March, 2020. Cases was defined as self-reported anosmia HP/ hyposmia HP in responders fewer than 4 weeks later (from start the of COVID-19 epidemic in Iran). Variables consist of clinical presentations, related past medical history, family history of recent respiratory tract infection MESHD respiratory tract infection HP and hospitalization. Results In this study 10069 participants aged TRANS 32.5 +/- 8.6 (7-78) years, 71.13% female TRANS and 81.68% non-smoker completed online checklist. They reported 10.55% a history of a trip out of home town and 1.1% hospitalization due to respiratory problems recently. From family members TRANS 12.17% had a history of severe respiratory disease MESHD in recent days and 48.23% had anosmia HP/ hyposmia HP. Correlation between the number of olfactory disorder and reported COVID-19 patients in all 31 provinces till 16th March 2020 was highly significant (Spearman correlation coefficient=0.87, p-Value<0.001). The onset of anosmia HP was sudden in 76.24% and till the time of filling the questionnaire in 60.90% of patients decreased sense of smell was constant. Also 83.38 of this patients had decreased taste sensation HP in association with anosmia HP. Conclusions It seems that we have a surge in outbreak of olfactory dysfunction happened in Iran during the COVID-19 epidemic. The exact mechanism of anosmia HP/ hyposmia HP in COVID-19 patients needs further investigations.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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