Corpus overview


MeSH Disease

Human Phenotype

Anxiety (493)

Insomnia (27)

Fatigue (15)

Pain (15)

Pneumonia (13)


    displaying 1 - 10 records in total 493
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    Rapid Support for older adults TRANS during the initial stages of the COVID-19 Pandemic: Results from a Geriatric Psychiatry helpline

    Authors: Anna-Sophia Wahl; Gloria S. Benson; Lucrezia Hausner; Sandra Schmitt; Annika Knoll; Adriana Ferretti-Bondy; Dimitri Hefter; Lutz Froelich

    doi:10.1101/2020.10.29.20218750 Date: 2020-10-29 Source: medRxiv

    Background: The COVID-19 pandemic and governmental lockdown measures disproportionally impacts older adults TRANS. This study presents the results from a psychiatric MESHD helpline for older adults TRANS in Mannheim, Germany, during the lockdown, set up to provide information and psychosocial support measures. We aim to elucidate the needs of older adults TRANS, their reported changes and the psychological impact during the initial stages of the health crisis. Methods: 55 older adults TRANS called the psychiatric MESHD helpline between April and June 2020. Information on demographics, previous diagnosis of psychiatric MESHD and somatic diseases as well as changes in daily life due to the pandemic was collected anonymously. Current mental health status was assessed using the depression MESHD HAMD-7 and the anxiety HP anxiety MESHD HAM-A scales. Results: Most callers were women, older adults TRANS (M = 74.69 years), single and retired. 69% of callers reported new or an increase in psychiatric symptoms MESHD, with anxiety HP anxiety MESHD and depressive symptoms MESHD being the most common ones. Age TRANS was significantly negatively correlated to higher levels of anxiety HP anxiety MESHD and depression symptoms. Individuals with a previous diagnosis of a psychiatric disease MESHD reported significantly higher levels of depressive MESHD and anxiety HP anxiety MESHD symptoms than those without a diagnosis. Conclusion: In older adults TRANS, the perceived psychological impact of the COVID-19 crisis appears to ameliorate with age TRANS. Individuals with a history of psychiatric disease MESHD are most vulnerable to negative mental health outcomes. Rapid response in the form of a geriatric helpline are useful initiatives to support the needs and the psychological well-being of older adults TRANS during a health crisis.

    Depression MESHD, Anxiety HP Anxiety MESHD and Stress among Health Care Professionals on Duty in COVID-19 Wards

    Authors: Maham Noor Afroz; Syeda Maria Hassan; Kanwal Bansari; Humza Faisal Siddiqui; Sana Irfan; Basma Ali; Hamza Sohail; Zoha Batool; Muhammad Khizar Memon; Sidra Memon; Faizan Shaukat

    id:10.20944/preprints202010.0559.v1 Date: 2020-10-27 Source:

    Introduction: COVID-19 pandemic has affected HCPs in multiple way. It has caused psychological impact in form of anxiety HP anxiety MESHD, depression MESHD, and insomnia HP insomnia MESHD. In this study, we aim to study and compare the stress level, anxiety HP anxiety MESHD and depression MESHD among HCPs who are posted in special COVID-19 units with the HCPs who are not posted in COVID-19 units.Methods: This cross-sectional study was conducted in June 2020, at various hospitals of Karachi, Pakistan. All health care professionals (HCPs) were invited to participate. A total of 301 HCPs completed this study, who were divided into two groups; those who are posted in COVID-19 ward (Group A) and those who are not (Group B). Psychological Impact was English version of the Depression Anxiety Stress MESHD Anxiety HP Stress Scale - 21 (DASS-21).Results: In Group A, 70.5% had moderate, severe, or extremely severe depression MESHD compared to 49.2% in group B. In Group A, 75.4% had moderate, severe, or extremely severe anxiety HP anxiety MESHD compared to 44.7% in group B. In Group A, 80.3% had moderate, severe or extremely severe stress compared to 54.2% in group B. Anxiety HP Anxiety MESHD, depression MESHD and stress were significantly higher in HCPs who were posted in COVID-19 ward compared to those who were not posted in COVID-19 wardConclusion: There was significantly higher anxiety HP anxiety MESHD, stress and depression MESHD in health care professionals posted in COVID-19 ward. Both the government and health care agencies should take responsibility for protecting the psychological well-being of health care communities all over the world and ensuring a healthy work environment.

    The impact of the COVID-19 pandemic on the mental health and wellbeing of UK healthcare workers

    Authors: James Gilleen; Aida Santaolalla; Lorena Valdearenas; Clara Salice; Monserrat Fuste; Alpan Raval; Luis Odorico Monteiro de Andrade; Leuridan Torres; Flavia Kelly Alvarenga Pinto; Francisco Marto Leal Pinheiro-Junior; Rebeca Valentim Leite; Amanda Carolina Abreu Felix Cavalcanti de Abreu; Rebecca Lucena Theophilo; Fernando Rodrigues Magalhaes; Susane Lindinalva da Silva; Carl Kendall

    doi:10.1101/2020.10.23.20218396 Date: 2020-10-27 Source: medRxiv

    Background There is an urgent need to understand the psychological impact the COVID-19 pandemic has had on UK healthcare workers (HCW). Aims To reveal risk and protective factors associated with poor mental wellbeing of HCW working during the COVID-19 pandemic in the UK. Method 2773 UK HCWs completed a survey between 22ndApril and 10th May 2020 containing scales measuring anxiety HP anxiety MESHD, depression MESHD, PTSD MESHD, and stress, and questions about roles and COVID-19-related factors including workplace preparation and risk management. Respondents were classified as high or low symptomatic on each mental health scale and logistic regression revealed risk and protective factors associated with each outcome. Change in wellbeing from pre to during COVID-19 was also quantified. Results A large proportion of UK HCW had high mental health symptoms. Fixed risk factors of poor mental health included being female TRANS, being frontline, pre-existing mental health diagnoses, and experience of stressful/ traumatic MESHD events. An additional set of controllable factors also significantly increased risk: PPE availability, workload, lack of COVID-19 preparation and training, and insufficient communication of clinical procedures. Resilience and sharing stress reduced risk, as did ethical support for those making treatment decisions. Allied HCW and managers were at elevated risk of high symptoms particularly PTSD MESHD. Wellbeing, especially of frontline workers, had significantly worsened compared to before COVID-19. Conclusions Poor mental wellbeing was prevalent in HCW during the UK COVID-19 response. A number of controllable factors should be targeted, and protective factors promoted, to reduce the detrimental effect of COVID-19 and other pandemics on HCW mental health.

    Perceived Risk and Distress related to COVID-19: Comparing Healthcare versus non-Healthcare Workers of Pakistan

    Authors: Dr. Adeel Abid; Dr. Hania Shahzad; Dr. Hyder Ali Khan; Dr. Suneel Piryani; Areeba Raza Khan; Dr. Fauziah Rabbani; iqra chowdry; muhammad Obaid; Iram Sabah; Misbah Kawoosa; Abdul Lone; Shahroz Nabi; Ishtiyaq Sumji; Nikoloz Chkhartishvili; Frédéric Limosin; Carl Kendall

    doi:10.1101/2020.10.23.20218297 Date: 2020-10-27 Source: medRxiv

    Background Healthcare workers (HCWs) find themselves susceptible to contracting COVID-19 or being the source of exposure for their family members TRANS. This puts them at a high risk of psychological distress which may compromise patient care. In this study we aim to explore the risk perceptions and psychological distress between HCWs and non-healthcare workers (NHCWs) in Pakistan. Methods A cross-sectional study was conducted in Pakistan using an online self-administered questionnaire. Respondents were categorized into HCWs (completed or aspiring to complete education in Medicine or allied fields) and NHCWs. HCWs were further categorized into front-line (direct patient care) and back-end HCWs. Results Data from 1406 respondents (507 HCWs and 899 NHCWs) was analyzed. No significant difference was observed between HCWs and NHCWs perception of susceptibility and severity towards COVID-19. Healthcare graduates perceived themselves (66% students vs. 80% graduates, p-value 0.011) and their family (67% students vs. 82% graduates, p-value 0.008) to be more susceptible to COVID-19 than the healthcare students. Frontline HCWs perceived themselves (83% frontline vs. 70% back-end, p-value 0.003) and their family (84% frontline vs. 72% back-end, p-value 0.006) as being more susceptible to COVID-19 than back-end healthcare professionals. Over half of the respondents were anxious (54% HCWs and 55% NHCWs). Female TRANS gender TRANS, younger age TRANS and having COVID-19 related symptoms had a significant effect on the anxiety HP anxiety MESHD levels of both HCWs and NHCWs. Conclusion Frontline HCWs, healthcare students, young people, females TRANS and individuals with lower income were at a higher risk of psychological distress MESHD due to the pandemic. Government policies should thus be directed at ensuring the mental well-being of frontline HCWs, and improving their satisfaction in order to strengthen health care delivery system.

    Predictors of PTSD MESHD, depression MESHD and anxiety HP anxiety MESHD in UK frontline health and social care workers during COVID-19.

    Authors: Talya Greene; Jasmine Harju-Seppanen; Mariam Adjeniji; Charlotte Steel; Nick Grey; Chris R Brewin; Michael A Bloomfield; Jo Billings; Jonatan Konfino; Juan Ignacio Brardinelli

    doi:10.1101/2020.10.21.20216804 Date: 2020-10-25 Source: medRxiv

    Objectives: The objectives of this study were to identify demographic, work-related and other predictors for clinically significant psychological distress, including PTSD MESHD, depression MESHD, and/or anxiety HP anxiety MESHD during the COVID-19 pandemic in UK frontline health and social care workers (HSCWs), and to compare rates of PTSD MESHD, depression MESHD and anxiety HP anxiety MESHD across different groups of HCSWs. Design: An online survey was conducted in the weeks following the initial peak in cases (27 May to 23 July 2020). Setting: The participants worked in a variety of healthcare roles UK hospitals, nursing or care homes and community settings. Participants: A convenience sample (n=1194) of frontline UK health and social care workers completed the survey (including allied healthcare professionals, carers, clinical support staff, nurses and midwives, and other health and social care roles). Main outcome measures: PTSD MESHD was assessed using the PTSD subscale of the International Trauma MESHD Questionnaire (ITQ); Depression MESHD assessed using the Patient Health Questionnaire-9 (PHQ-9); Anxiety HP Anxiety MESHD was assessed using the Generalized Anxiety HP Anxiety MESHD Disorder Scale (GAD-7). Results: Logistic regression analyses examined predictors for depression MESHD, anxiety HP anxiety MESHD and PTSD MESHD separately, and also investigated the predictors of meeting the criteria for at least one of the three conditions. Over 57% of respondents met the threshold for clinically significant PTSD MESHD, anxiety HP anxiety MESHD or depression, and symptom levels were reasonably high and comparable across occupational groups. Participants who were more concerned about infecting others, who felt they could not talk with their managers, who reported feeling stigmatised due to their role and who had not had reliable access to personal protective equipment (PPE) were more likely to meet criteria for a clinically significant mental disorder MESHD. Being redeployed during the pandemic, and having had COVID were associated with a higher likelihood of meeting criteria for PTSD MESHD. Higher household income was associated with reduced odds for a mental disorder MESHD. Conclusions: This study identifies predictors of clinically significant distress during COVID-19 and highlights the need for reliable access to PPE. Further research should investigate mental disorders MESHD in under-represented HSCW groups and examine barriers to communication between managers and staff. Identifying risk factors for PTSD MESHD, depression MESHD and anxiety HP anxiety MESHD among HSCWs, and providing treatment for those who need it, is critical given that subsequent waves of COVID-19 and other healthcare crises are inevitable.

    Social and Psychiatric Effects of COVID-19 Pandemic and Distance Learning On High School Students: A Cross-Sectional Web-Based Survey Comparing Turkey and Denmark

    Authors: Lara Selin Seyahi; Seyda Gul Ozcan; Necdet Sut; Ayumi Mayer; Burc Cagri Poyraz; Chris R Brewin; Michael A Bloomfield; Jo Billings; Jonatan Konfino; Juan Ignacio Brardinelli

    doi:10.1101/2020.10.21.20217406 Date: 2020-10-25 Source: medRxiv

    Objective: In this study we investigated the socio-psychological effects of both the pandemic and distance learning on high school students in Turkey and Denmark. We aimed to assess whether there were any differences a) between students attending public or private schools in Turkey and b) between two countries having different approaches to pandemic and considerable socio-cultural and economic differences. Methods: We conducted a web-based questionnaire study in a cross-sectional design using Survey Monkey platform and sent out via social media to high school students from Turkey and Denmark. The survey collected socio-demographic data, several variables associated with pandemic and distance education and their effects on social life and psychological status. Additionally, emotional status was assessed using positive (PA) and negative affects (NA) schedule (PANAS). The survey ran from July 3 and August 31 2020. Results: We studied 565 (mean age TRANS: 16.5{+/-}1.0) Turkish and 92 (mean age TRANS:17.7{+/-}1.0) Danish students, of whom the majority were female TRANS adolescents (63% vs 76%). Students educated in public (47.6%) and private high schools (52.4%) were nearly similar in number in Turkish group, whereas in the Danish sample almost all students were from public school (98.9%). Turkish students were significantly more likely to be compliant with the pandemic related restrictions. Besides that, there were significant socio-economic disparities between Turkish and Danish students and also within Turkey between public and private school students. Turkish online education system was significantly less adequate and satisfactory compared to the Danish system. These were even worse for those who were attending public schools in Turkey. Regardless of the socio-economic differences, the majority of the students in both countries has been negatively affected by the pandemic and related restrictions and had a negative opinion about distance education. This was also true for the PANAS scores. The total scores of PANAS were similar between Turkish and Danish students (PA: 27.0{+/-} 7.6 versus 25.8{+/-} 5.6; NA: 24.8{+/-}7.5 versus 24.5{+/-}7.3) and also within Turkey between public and private school students (PA: 26.8{+/-}7.5 versus 27.1{+/-} 7.6; NA: 24.7{+/-}7.2 versus 25.0{+/-}7.8). While female TRANS students were significantly more severely affected in the Turkish group, no such gender TRANS differences were observed in the Danish group. Additionally, considerable portion of the students in Turkey and Denmark expressed loneliness (55.2% vs 59.8%, p<0.706), boredom (71.2% vs 58.7%, p=0.019) and anxiety HP anxiety MESHD towards the future (61.4% vs 22.8%, p<0.001). Decreased physical activity, sleep problems, eating disorders MESHD and domestic abuse were other complaints. Conclusions: Adolescents from both countries have been severely affected by the pandemic and its related restrictions and expressed negative views about distance education. Turkish online education system seemed to be less satisfactory when compared to Danish system and within Turkey, public school students had significantly more disadvantages compared to those attending private schools. Despite the fact that there were several socio-economic inequalities among students, in general, there were no robust significant differences regarding psychological status and opinion about distance learning, indicating a global worsening of emotional status during pandemic.

    Associations between Affect, Physical Activity, and Anxiety HP Anxiety MESHD Among US Children TRANS During COVID-19

    Authors: Jasmin M Alves; Alexandra G Yunker; Alexis W Defendis; Anny H Xiang; Katie A Page; Joe DeRisi; Bryan Greenhouse; Jill Hakim; Keirstinne Turcios; Lee Atkinson-McEvoy; Raphael Hirsch; Roberta L Keller; Theodore Ruel; Auritte Cohen-Ross; Araceli Leon; Naomi Bardach; Aaron F Carlin; Alex E. Clark; Laura Berreta; Daniel Maneval; Felix Frueh; Brett L Hurst; Hong Wang; Klaudia I Kocurek; Frank M Raushel; Jair L. Siqueira-Neto; Thomas D Meek; James H McKerrow

    doi:10.1101/2020.10.20.20216424 Date: 2020-10-23 Source: medRxiv

    We investigated how emotional responses (positive and negative affect), physical activity (PA), and sedentary behaviors related to anxiety HP anxiety MESHD among US children TRANS during the COVID 19 pandemic. Sixty four typically developing children TRANS (63% girls) age TRANS 9 to 15 years old completed two virtual visits during height of stay at home measures between April 22 to July 29, 2020. Children TRANS completed 24 hour PA recalls SERO, state portion of State-Trait Anxiety HP Anxiety MESHD Inventory for Children TRANS (STAIC), and the shortened 10 item Positive and Negative Affect Schedule for Children TRANS (PANAS C). Children TRANS reported state anxiety HP anxiety MESHD scores that were more than 5 standard deviations greater than values from healthy pediatric populations prior to the pandemic. Children TRANS with higher positive affect and who reported more time in PA reported less state anxiety HP anxiety MESHD. Sedentary and leisure screen time were positively correlated with negative affect. Our findings suggest that maintaining positive affect, engaging in PA, and limiting leisure screen time may be important for child TRANS mental health during stressful periods.


    Authors: Leodoro Labrague; Janet De los Santos; Afshin Borhani Haghighi; Daniyal Salehi; Hossein Molavi Vardanjan; Maryam Poursadeghfard; Isabelle Delpierre; Sophie Henrard; Niloufar Sadeghi; Jean-Christophe Goffard; Serge Goldman; Xavier De Tiège; Javier Colomina; David Navarro

    doi:10.1101/2020.10.18.20214692 Date: 2020-10-20 Source: medRxiv

    Objectives: To determine the prevalence SERO rate as well as the predictors of coronaphobia in frontline hospital and public health nurses. Design: This study used a cross-sectional research study involving 736 nurses working in COVID-19 designated hospitals and health units in Region 8, Philippines. Four structured self-report scales were used, including the Coronavirus Anxiety MESHD Anxiety HP Scale, the Brief Resilience Scale, the Perceived Social Support Questionnaire, and the single-item measure for perceived health. Results: The prevalence SERO rate of coronaphobia was 54.76% (n = 402): 37.04% (n = 130) in hospital nurses and 70.91% (n = 273) in public health nurses. Additionally, nurses gender TRANS (being female TRANS), marital status (being married), job status (contracted status), and personal resilience were identified as predictors of COVID-19 anxiety HP anxiety MESHD. A small proportion of nurses was willing (19.94%, n = 70) and fully prepared (9.40%, n = 33) to manage and care for coronavirus patients. Conclusion: Coronaphobia is prevalent among frontline Filipino nurses, particularly among public health nurses. Interventions to address coronaphobia among frontline nurses in the hospital and community should consider the predictors identified. By increasing personal resilience in nurses through theoretically-driven intervention, coronaphobia may be alleviated.

    Experiences of Women Who Gave Birth MESHD in US Hospitals During the COVID-19 Pandemic

    Authors: Elizabeth Mollard; Amaya Wittmaack; Anna Nemudraia; Laina N. Hall; Pushya Krishna; Tanner Wiegand; Royce A. Wilkinson; Deann T. Snyder; Jodi F. Hedges; Mark A. Jutila; Matthew P. Taylor; Blake Wiedenheft; Jess Shen; Christine Bruce; Bryn Hazlett; Susan Poutanen; Lilliana Attisano; Rod Bremner; Benjamin Blencowe; Tony Mazzulli; Hong Han; Laurence Pelletier; Jeffrey L Wrana

    doi:10.1101/2020.10.15.20213504 Date: 2020-10-20 Source: medRxiv

    The purpose of this study was to describe the experiences of women who gave birth in a US hospital during the COVID-19 pandemic. Women who gave birth between March and July 2020 completed a survey on the experience of giving birth during a pandemic. 885 women were consented and participated in the study. 22.5% of women reported hypertension HP hypertension MESHD, 33.8% reported anxiety HP anxiety MESHD, 18.6% reported depression MESHD, and 1.13% reported testing positive for COVID-19. 61% of women reported inadequate support for childbirth, and 20.5% reported that they did not feel safe giving birth in the hospital. Women who tested positive for COVID-19 were more likely to be of Asian race, have a cesarean section, not have a birth partner present, and discontinue breastfeeding before 6 weeks. Pandemic related changes to maternity care practices may have impacted birthing women's perceptions of safety and support in the hospital environment and affected symptoms of stress. Healthcare policy and maternity care practices should promote feelings of safety and control and overall experience for women giving birth in the hospital during a pandemic.

    Anxiety HP Anxiety MESHD Levels among Healthcare Professionals during Covid-19 Pandemic: A Multifactorial Study

    Authors: Arif Malik; Muhammad Mansoor Hafeez; Muhammad Asim Rana; Sulayman Waquar; rabail alam; Ana I Bento; Daisuke Yoneoka; Seiichi Ichikawa; Daisuke Mizushima; Shingo Iwami; Ferenc E Mózes; Adam J Lewandowski; Eric O Ohuma; David Holdsworth; Hanan Lamlum; Myles J Woodman; Catherine Krasopoulos; Rebecca Mills; Flora A Kennedy McConnel; Chaoyue Wang; Christoph Arthofer; Frederik J Lange; Jesper Andersson; Mark Jenkinson; Charalambos Antoniades; Keith M Channon; Mayooran Shanmuganathan; Vanessa M Ferreira; Stefan K Piechnik; Paul Klenerman; Christopher Brightling; Nick P Talbot; Nayia Petousi; Najib M Rahman; Ling-Pei Ho; Kate Saunders; John R Geddes; Paul Harrison; Kyle Pattinson; Matthew J Rowland; Brian Angus; Fergus Gleeson; Michael Pavlides; Ivan Koychev; Karla L Miller; Clare Mackay; Peter Jezzard; Stephen M Smith; Stefan Neubauer

    doi:10.1101/2020.10.14.20212167 Date: 2020-10-18 Source: medRxiv

    The current study focuses on psychological stress level among doctors, estimated by calculating anxiety HP anxiety MESHD score. For the assessment of anxiety HP anxiety MESHD levels, the GAD-7 scale was used. Chi-Square test and Odd ratios were calculated among the exposed and not exposed groups involved in the management of COVID-19 patients. Results revealed increased anxiety HP anxiety MESHD levels in the exposed group. Besides, the availability of personal protective equipments and stress from the family to quit the job were the substantial contributing factors that increased anxiety HP anxiety MESHD. Based on the results, it is proposed that the concern administrative authorities should consider these findings to facilitate medical healthcare professionals.

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MeSH Disease
Human Phenotype

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