Corpus overview


MeSH Disease

Human Phenotype


    displaying 1 - 10 records in total 278
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    The Effect of Financial Anxiety HP on the Insurance Behavior of Russian Citizens in the Context of the 2019-nCoV Pandemic

    Authors: Olga Medyanik

    id:10.20944/preprints202008.0012.v1 Date: 2020-08-02 Source:

    In the context of the economic and political uncertainty associated with the 2019-nCoV pandemic, it is necessary to determine the socio-psychological factors involved in the transformation of the behavior of insurance consumers under the influence of a biogenic threat. This study measures financial anxiety HP and its impact on the insurance behavior of Russian citizens. The correlation, comparative, and regression analyses of the financial anxiety HP of Russian citizens cover three stages of observation: before the start of the 2019 nCoV pandemic (“FA up to 19 nCoV; N = 766), during the period of quarantine measures announced in Russia in March 2020 (“FA 19-nCoV-1”; N = 856), and after the relaxation of quarantine measures at the end of April 2020 (“FA 19-nCoV-2”; N = 963).Psychological analysis data were obtained from the online survey “Financial anxiety HP (in the context of insurance)”. The questionnaire is psychometrically reliable and easy to use. It includes five measurement scales: MR1—Physical manifestations of financial incentive anxiety HP, MR2—With money shortages and financial uncertainty, MR3—The value of insurance coverage, MP4—Financial Confidence, and MR5—Perception of insurance and investment risks. It was found that Russian citizens consider it important to have insurance coverage for a “rainy day”, and they showed confidence in the insurance market during the biogenic crisis. However, unfortunately, during the 19-nCoV-1 and 19-nCoV-2 periods, Russian citizens did not feel financially secure, unlike in the period before 19-nCoV. Women showed high scores for physical manifestations of financial anxiety HP and low financial confidence in the future, in contrast to men, regardless of the observation period.

    Loneliness, physical activity and mental health during Covid-19: a longitudinal analysis of depression and anxiety HP between 2015 and 2020.

    Authors: Byron Creese; Zunera Khan; William Henley; Anne Corbett; Miguel Vasconcelos Da Silva; Kathryn Mills; Natalie Wright; Ingelin Testad; Dag Aarsland; Clive Ballard

    doi:10.1101/2020.07.30.20165415 Date: 2020-08-02 Source: medRxiv

    Background Loneliness and physical activity are important targets for research into the impact of COVID-19 because they have established links with mental health, could be exacerbated by social distancing policies and are potentially modifiable. Methods We analysed mental health data collected during COVID-19 from adults TRANS aged TRANS 50 and over alongside comparable annual data collected between 2015 and 2019 from the same sample. Trajectories of depression (PHQ-9) and anxiety HP (GAD-7) were analysed with respect to loneliness, physical activity levels and a number of socioeconomic and demographic characteristics using zero-inflated negative binomial regression. Findings 3,281 people completed the COVID-19 mental health questionnaire, all had at least one data point prior to 2020. In 2020, the adjusted PHQ-9 score for loneliness was 3.2. (95% CI: 3.0-3.4), an increase of one point on previous years and 2 points higher than people not rated lonely, whose score did not change in 2020 (1.2, 95% CI: 1.1-1.3). PHQ-9 was 2.6 (95% CI: 2.4-2.8) in people with decreased physical activity, an increase of 0.5 on previous years. In contrast, PHQ-9 in 2020 for people whose physical activity had not decreased was 1.7 (95% CI: 1.6-1.8), similar to previous years. A similar relationship was observed for GAD-7 though the differences were smaller and the absolute burden of symptoms lower. Interpretation After accounting for pre-COVID-19 trends, we show that experiencing loneliness and decreased physical activity are risk factors for worsening mental health during the pandemic. Our findings highlight the need to examine policies which target these potentially modifiable risk factors.

    Effects of COVID-19 in Endocrine Patients: Results of a Sicilian Experience

    Authors: Elisabetta Morini; Rosanna Palmeri; Giuseppa Maresca; Lilla Bonanno; Maria Cristina De Cola; Adriana Andaloro; Santina Caliri; Placido Bramanti; Francesco Corallo

    id:10.20944/preprints202008.0041.v1 Date: 2020-08-02 Source:

    In March 2020 the World Health Organization declared the “pandemic state” due to COVID-19 imposing strict confinement of the world population. People were forced to spend more time at home, changing some daily routines, including social interactions HP social interactions TRANS, the possibility to perform sports, and diet habits. These changes could exert a greater impact on patients suffering from chronic diseases MESHD, such as endocrine patients. This study aimed to assess the effects of Covid-19 induced quarantine on daily habits in a group of patients with endocrine disorders, focusing on food consumption, eating, and sleep habits during the confinement. Eighty-five endocrine patients were enrolled. A structured interview was administered investigating: socio-demographic information, general medical conditions and habits adopted during the quarantine. All patients underwent the Spielberger State Anxiety HP Inventory (STAI-Y1) to assess state anxiety HP. Subjects had mainly a sedentary lifestyle. We found a significant increase in the number of cigarettes in smokers, an increase of meals consumed during the confinement and a high rate of sleep disorder occurrence, especially insomnia HP. The changes of daily habits were, probably, due to the alterations of routine, that determined more bore and inactivity during the day.

    Outpatient screening of health status and lifestyle among post-bariatric patients during the Covid-19 pandemic in Sao Paulo, Brazil.

    Authors: Karla Fabiana Goessler; Carolina Ferreira Nicoletti; Diego Augusto Nunes Rezende; Sofia Mendes Sieczkowska; Gabriel Perri Esteves; Rafael Genario; Gersiel Nascimento Oliveira-Junior; Kamila Meireles; Ana Jessica Pinto; Michele Nakahara-Melo; Roberto Cleva; Marco Aurelio Santo; John Kirwan; Hamilton Roschel; Bruno Gualano

    doi:10.1101/2020.07.30.20165068 Date: 2020-08-02 Source: medRxiv

    Background/Objectives: This was an out-of-hospital screening of health status and lifestyle during the Covid-19 pandemic in post-operative bariatric patients from Sao Paulo, Brazil, prevented from face-to-face health care. Subjects/Methods: In this cross-sectional study, 66 patients were remotely (via phone call) and in-person (by home visit) assessed for health status and lifestyle habits. Results: Mean age TRANS was 47.4 years. Patients were obese grade I (30.0%), II (22.0%), and III (30.0%), and 94.2% had above reference waist circumference values. Sixty-four percent displayed high blood SERO pressure, whereas 24% showed CRP levels above normal range. Nineteen percent of patients reported irregular use of nutritional supplementation and 6.0% reported binge eating habits. Thirty-three exhibited symptoms of depression. Mild-to-moderate and moderate-to-severe anxiety HP symptoms were reported by 27.4% and 11.3% of the patients; 4.5% exhibited suicidal ideation HP and were referred to a specialist for healthcare. Of relevance, inactive patients (59.6%) had poorer global mental and physical health scores as compared to active peers (both p<0.05). Conclusion: This out-of-hospital screening revealed that the absence of face-to-face health care due to the Covid-19 pandemic is associated with suboptimal status of physical and mental health as well as lifestyle inadequacies among patients who have recently undergone bariatric surgery.

    Perception of and anxiety HP about COVID-19 infection MESHD infection and risk TRANS infection and risk TRANS and risk behaviors for spreading infection MESHD: An international comparison

    Authors: Akihiro Shiina; Tomihisa Niitsu; Osamu Kobori; Keita Idemoto; Tasuku Hashimoto; Tsuyoshi Sasaki; Yoshito Igarashi; Eiji Shimizu; Michiko Nakazato; Kenji Hashimoto; Masaomi Iyo

    doi:10.1101/2020.07.30.228643 Date: 2020-07-30 Source: bioRxiv

    To control the spread of the newly developed corona viral infection MESHD diseases MESHD (COVID-19), peoples appropriate precautionary behaviors should be promoted. We conducted a series of online questionnaire survey, to gather a total of 8,000 citizens responses on March 27-28, 2020 in Japan and April 17-21 in the UK and Spain. Compared to Japan, the knowledge and anxiety HP level and the frequency of precautionary behaviors were higher in the UK and Spain. Participants with infected acquaintances were more concerned about COVID-19. However, participants in the UK rarely wore a medical mask. Participants in the UK and Spain were eager to get information about COVID-19 compared to those in Japan. The participants in Spain tended not to trust official information and to believe specialists' comments instead. The urgency of the spread of COVID-19, cultural backgrounds, and recent political situations appear to contribute to the differences among countries revealed herein.

    Persistent fatigue MESHD fatigue HP following SARS-CoV-2 infection MESHD is common and independent of severity of initial infection MESHD

    Authors: Liam Townsend; Adam H Dyer; Karen Jones; Jean Dunne; Rachel Kiersey; Fiona Gaffney; Laura O'Connor; Aoife Mooney; Deirdre Leavy; Katie Ridge; Catherine King; Fionnuala Cox; Kate O'Brien; Joanne Dowds; Jamie Sugrue; David Hopkins; Patricia Byrne; Tara Kingston; Cliona Ni Cheallaigh; Parthiban Nadarajan; Anne Marie McLaughlin; Nollaig M Bourke; Colm Bergin; Cliona O'Farrelly; Ciaran Bannan; Niall Conlon

    doi:10.1101/2020.07.29.20164293 Date: 2020-07-30 Source: medRxiv

    Fatigue MESHD Fatigue HP is a common symptom in those presenting with symptomatic COVID-19 infection MESHD. However, it is unknown if COVID-19 results in persistent fatigue MESHD fatigue HP in those recovered from acute infection MESHD. We examined the prevalence SERO of fatigue MESHD fatigue HP in individuals recovered from the acute phase of COVID-19 illness using the Chalder Fatigue MESHD Fatigue HP Score (CFQ-11). We further examined potential predictors of fatigue MESHD fatigue HP following COVID-19 infection MESHD, evaluating indicators of COVID-19 severity, markers of peripheral immune activation and circulating pro-inflammatory cytokines. Of 128 participants (49.5 {+/-} 15 years; 54% female TRANS), more than half reported persistent fatigue MESHD fatigue HP (52.3%; 45/128) at 10 weeks (median) after initial COVID-19 symptoms. There was no association between COVID-19 severity (need for inpatient admission, supplemental oxygen or critical care) and fatigue MESHD fatigue HP following COVID-19. Additionally, there was no association between routine laboratory markers of inflammation MESHD and cell turnover (leukocyte, neutrophil or lymphocyte counts, neutrophil-to-lymphocyte ratio, lactate dehydrogenase, C-reactive protein) or pro-inflammatory molecules (IL-6 or sCD25) and fatigue MESHD fatigue HP post COVID-19. Female TRANS gender TRANS and those with a pre-existing diagnosis of depression/ anxiety HP were over-represented in those with fatigue MESHD fatigue HP. Our findings demonstrate a significant burden of post-viral fatigue MESHD fatigue HP in individuals with previous SARS-CoV-2 infection MESHD after the acute phase of COVID-19 illness. This study highlights the importance of assessing those recovering from COVID-19 for symptoms of severe fatigue MESHD fatigue HP, irrespective of severity of initial illness, and may identify a group worthy of further study and early intervention.

    The Impact of COVID-19 on Mental Health outcomes among hospital fever MESHD fever HP clinic attendants across Nepal: A community-based cross-sectional study

    Authors: Hridaya Raj Devkota; Tula Ram Sijali; Ramji Bogati; Meraj Ahmad; Karuna Laxmi Shakya; Pratik Adhikary

    doi:10.1101/2020.07.28.20163295 Date: 2020-07-29 Source: medRxiv

    Background: The COVID 19 pandemic has been creating a panic and distressing situations among the entire population globally including Nepal. No study has been conducted assessing the psychological impact of this pandemic on the general public in Nepal. The objective of this study is to assess the mental health status during COVID 19 outbreak and explore the potential influencing factors among the population attending the hospital fever MESHD fever HP clinics with COVID 19 symptoms. Methods: A cross sectional survey was conducted between May to June, 2020 with a sample of 645 participants aged TRANS 18 and above in 26 hospitals across Nepal. Telephone interviews were conducted using a semi-structured questionnaire along with a validated psychometric tool, the Depression, Anxiety HP and Stress (DASS21) scale. The metrics and scores of symptoms and their severity were created and analyzed. Multivariate logistic regression was used to determine the association of potential covariates with outcome variables. Results: The prevalence SERO of anxiety HP, depression and stress were 14%, 7% and 5% respectively. Participants from Bagmati province reported higher level of anxiety HP (OR 3.87, 95% CI 1.42 10.59), while stress (OR 4.78, 95% CI 1.09 21.29) and depressive symptoms (OR 3.37, 95% CI 1.10 10.35) observed higher among the participants in Province 1. Women were more at risk of anxiety HP (OR 4.26, 95% CI 2.21 8.20) and depression (2.75, 95% CI 1.16 6.51) than men. Similarly, people with primary level education found more prone to all factors, stress (OR 20.35, 95% CI 2.06 201.19), anxiety HP (OR 3.10, 95% CI 1.24 7.91), and depression (OR 4.41, 95% CI 1.29 15.07). More farmers than labors showed higher odds (OR 2.25, 95% CI 1.01 5.01) for anxiety HP, while individuals surveyed who reported their health status as poor-had higher odds (OR 5.95, 95% CI 1.08 32.68) for depression. Also, people currently living in rented houses reported more stress (OR 3.11, 95% CI 1.07 9.05) and those living far from family reported higher rates of depressive symptoms (OR 3.57, 95% CI 1.01 12.58). Conclusion: The study identified increased prevalence SERO of stress, anxiety HP and depressive symptoms during the initial stage of COVID 19 pandemic in Nepal. Considering the findings, there is urgent need to develop and implement appropriate community-based mental health programs targeting individuals who have had COVID 19 symptoms and who are prone to develop adverse mental health outcomes. Key words: COVID 19, Depression, Anxiety HP, Stress, Pandemic, Public Health, Nepal

    Mental Health of Medical Workers During the COVID-19 Pandemic in Russia: Results of a Cross-Sectional Study

    Authors: Egor Bachilo; Juliy Barylnik; Andrey Shuldyakov; Alexander Efremov; Dmitiy Novikov

    doi:10.1101/2020.07.27.20162610 Date: 2020-07-29 Source: medRxiv

    This is the first study in Russia regarding the mental health of medical workers during a pandemic. In this survey, the study of medical workers during pandemic COVID-19 in Russia reported high rates of symptoms of depression and anxiety HP. There is a higher risk of developing symptoms of anxiety HP and depression among young employees working directly in high-risk areas of the infection MESHD. Protecting medical workers is an important component of public health measures for addressing the COVID-19 pandemic. Special measures to improve the mental health of medical workers should be based on their needs. Special attention needs to be paid to young medical workers working in areas with a high risk of infection TRANS risk of infection TRANS infection MESHD.

    Impact of the COVID-19 Pandemic on the Short-term Course of Obsessive-Compulsive Disorder

    Authors: Lavanya P Sharma; Srinivas Balachander; Abel Thamby; Mahashweta Bhattacharya; Chethana Kishore; Vandita Shanbhag; Jaisoorya TS; Janardhanan C Narayanaswamy; Shyam Sundar Arumugham; YC Janardhan Reddy

    doi:10.1101/2020.07.26.20162495 Date: 2020-07-29 Source: medRxiv

    Background: There is an understandable concern that obsessive-compulsive disorder (OCD) may worsen during the COVID-19 pandemic, but there is little empirical data. We report the impact of COVID-19 pandemic on the short-term course of OCD. We also assessed for predictors of relapse and emergence of COVID-19-themed obsessive-compulsive symptoms. Methods: A cohort of patients with a primary diagnosis of OCD (n=240) who were on regular follow-up at a tertiary care specialty OCD Clinic in India were assessed telephonically, about 2 months after the declaration of the pandemic ('pandemic' cohort). Data from the medical records of an independent set of patients with OCD (n=207) who were followed-up during the same period, one year prior, was used for comparison (historical controls). Results: The 'pandemic' group and historical controls did not differ in the trajectories of the Yale-Brown Obsessive-Compulsive Scale (YBOCS) scores (Chi-square for likelihood-ratio test of the Group x Time interaction = 2.73, p= 0.255) and relapse rate [21% vs 20%, adjusted odds ratio = 0.81 (95% CI 0.41 -1.59, p=0.535]. Pre-existing contamination symptoms and COVID-19-related health anxiety HP measured by the COVID-Threat Scale did not predict relapse. Only a small proportion of patients (6%) reported COVID-19-themed obsessive-compulsive symptoms. Limitations: Follow-up 2 months after pandemic declaration may be too early understand the true impact. Conclusions: The COVID-19 pandemic, at least in the short-run, did not influence the course of illness in those who were on medications. It would be pertinent to evaluate the long-term impact of the pandemic on the course of OCD.

    Canadian Emergency MESHD Medicine and Critical Care Physician Perspectives on Pandemic Triage in COVID-19

    Authors: Ali Mulla; Blair L. Bigham; Andrea Frolic; Michael D. Christian

    doi:10.21203/ Date: 2020-07-28 Source: ResearchSquare

    Purpose: Local and regional policies to guide the allocation of scarce critical care resources have been developed, but the views of prospective users are not understood. We sought to investigate the perspectives of Canadian acute care physicians towards triaging scarce critical care resources in the COVID-19 pandemic. Methods: We rapidly deployed a brief survey to Canadian emergency MESHD and critical care physicians in April 2020 to investigate current attitudes towards triaging scarce critical care resources and identify subsequent areas for improvement. Descriptive and between-group analyses along with thematic coding were used.Results: The survey was completed by 261 acute care physicians. Feelings of anxiety HP related to the pandemic were common (65%), as well as fears of psychological distress if required to triage scarce resources (77%). Only 49% of respondents felt confident in making resource allocation decisions. Both critical care and emergency MESHD physicians favored multidisciplinary teams over single physicians to allocate scarce critical care resources. Critical care physicians were supportive of decision making by teams not involved in patient care (3.4/5 vs 2.9/5 p=0.04), whereas emergency MESHD physicians preferred to maintain their involvement in such decisions (3.4/5 vs 4.0/5 p=0.007). Free text responses identified five themes for subsequent action including the need for further guidance on existing triage policies, ethical support in decision making, medico-legal protection, additional tools for therapeutic communications, and healthcare provider psychological support.  Conclusion: There is an urgent need for collaboration between policymakers and frontline physicians to develop critical care resource triage policies that wholly consider the diversity of provider perspectives across practice environments. 

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MeSH Disease
Human Phenotype

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