Corpus overview


Overview

MeSH Disease

Cough (4)

Headache (4)

Nausea (4)

Fever (3)

Fatigue (3)


Human Phenotype

Cough (4)

Headache (4)

Skin rash (4)

Fever (3)

Fatigue (3)


Transmission

Seroprevalence
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    Analysis of the Primary Presenting Symptoms and Hematological Findings of COVID-19 Patients in Bangladesh

    Authors: Abu Taiub Mohammed Mohiuddin Chowdhury; Md Rezaul Karim; H.M. Hamidullah Mehedi; Mohammad Shahbaz; Md Wazed Chowdhury; Guo Dan; Shuixiang He

    id:10.20944/preprints202006.0275.v1 Date: 2020-06-21 Source: Preprints.org

    Objective: SARS-Cov-2 infection MESHD or COVID-19 is a global pandemic. From the time of identification to till, multiple clinical symptoms and parameters have been identified by the researchers of various countries and regions regarding the diagnosis and presentations of COVID-19 disease MESHD. In this manuscript, we investigated the primary symptoms and basic hematological presentations of SARS-CoV-2 infection MESHD among the Bangladeshi patients. Methodology: We have collected the disease MESHD history of mild to moderate degree of COVID-19 patients; hematological and biochemical on admission reports of moderate degree COVID-19 patients. All of them were tested positive for SARS-CoV-2 by RT-PCR in different institutes in Bangladesh. Results: According to this study though COVID-19 patients in Bangladesh commonly presented with fever MESHD fever HP, cough MESHD cough HP, fatigue MESHD fatigue HP, shortness of breath, and sore throat, but symptoms like myalgia MESHD myalgia HP, diarrhea MESHD diarrhea HP, skin rash HP, headache MESHD headache HP, Abdominal pain MESHD Abdominal pain HP/cramp, nausea MESHD nausea, vomiting HP, vomiting MESHD, restlessness HP, and a higher temperature of >1000F have a greater presentation rate and more frequent than other published studies. CRP and Prothrombin time was found to increase in all the patients. Serum SERO ferritin, ESR, SGPT, and D-Dimer were found increased among 53.85%, 80.43, 44%, and 25% patients respectively. 17.39% of the patients had leukocytosis MESHD leukocytosis HP and neutrophilia HP. 28.26% of patients presented with lymphocytopenia. 62.52% of patients had mild erythrocytopenia. Conclusion: Despite some similarities, our study has evaluated a different expression in presenting symptoms in the case of COVID-19 patients in Bangladesh. CRP, Prothrombin time, serum SERO ferritin, ESR, SGPT, D-Dimer, erythrocytopenia, and lymphocytopenia can be initial diagnostic hematological findings and assessment for prognosis COVID-19 disease MESHD. Also, gender TRANS variations have a different scenario of clinical and laboratory appearance in this region.

    Differentiating coronavirus disease MESHD 2019 (COVID-19) from influenza and dengue MESHD

    Authors: Tun-Linn Thein; Li Wei Ang; Barnaby Edward Young; Mark IC Chen; Yee-Sin Leo; David Chien Lye

    doi:10.21203/rs.3.rs-36343/v1 Date: 2020-06-18 Source: ResearchSquare

    Background: The novel coronavirus disease MESHD 2019 (COVID-19) presents with non-specific clinical features. This may result in misdiagnosis or delayed diagnosis, and lead to further transmission TRANS in the community. We aimed to derive early predictors to differentiate COVID-19 from influenza and dengue MESHD.Methods: The study comprised 126 patients with COVID-19, 171 with influenza and 180 with dengue MESHD, who presented within 5 days of symptom onset TRANS. All cases were confirmed TRANS by reverse transcriptase polymerase chain reaction tests. We used logistic regression models to identify clinical characteristics and laboratory markers in classifying COVID-19 versus influenza, and COVID-19 versus dengue MESHD. The performance SERO of the models were evaluated using receiver operating characteristic curves (ROC).Results: Shortness of breath was the strongest predictor in the models for differentiating between COVID-19 and influenza, followed by diarrhoea. Higher lymphocyte count was predictive of COVID-19 versus influenza and versus dengue MESHD. In the model for differentiating between COVID-19 and dengue MESHD, patients with cough MESHD cough HP and higher platelet count were at increased odds of COVID-19, while headache MESHD headache HP, joint pain MESHD pain HP, skin rash HP and vomiting MESHD vomiting/nausea HP/ nausea MESHD were indicative of dengue MESHD. The area under the ROC was 0.92 for flu model and 0.99 for dengue MESHD model.Conclusion: Models based on clinical features and simple laboratory markers for differentiating COVID-19 from influenza and dengue MESHD, which possess good predictive performance SERO, can serve as a useful tool for primary care physicians to determine if further investigations or referrals would be required.

    "Analysis of the Primary Presenting Symptoms and Hematological Findings of COVID19 Patients in Bangladesh"

    Authors: Abu Taiub Mohammed Mohiuddin Chowdhury; Md Rezaul Karim; H.M.Hamidullah Mehedi; Mohammad Shahbaz; Md Wazed Chowdhury; Dan Guo; Shuixiang He

    doi:10.21203/rs.3.rs-35016/v1 Date: 2020-06-12 Source: ResearchSquare

    Background:SARS-Cov-2 infection MESHD or COVID-19 is a global pandemic. From the time of identification to till, multiple clinical symptoms and parameters have been identified by the researchers of various countries and regions regarding the diagnosis and presentations of COVID19 disease MESHD. In this manuscript, we investigated the primary symptoms and basic hematological presentations of SARS-CoV-2 infection MESHD among the Bangladeshi patients. Methodology: We have collected the disease MESHD history of mild to moderate degree of COVID19 patients; hematological and biochemical on admission reports of moderate degree COVID19 patients.  All of them were tested positive for SARS-CoV-2 by RT PCR in different institutes in Bangladesh. Results: According to this study though COVID19 patients in Bangladesh commonly presented with fever MESHD fever HP, cough MESHD cough HP, fatigue MESHD fatigue HP, shortness of breath, and sore throat, but symptoms like myalgia MESHD myalgia HP, diarrhea MESHD diarrhea HP, skin rash HP, headache MESHD headache HP, Abdominal pain MESHD Abdominal pain HP/cramp, nausea MESHD nausea, vomiting HP, vomiting MESHD, restlessness HP, and a higher temperature of >1000F have a greater presentation rate and more frequent than other published studies. CRP and Prothrombin time was found to increase in all the patients. Serum SERO ferritin, ESR, SGPT, and D-Dimer were found increased among 53.85%, 80.43, 44%, and 25% patients respectively. 17.39% of the patients had leucocytosis and neutrophilia HP. 28.26% of patients presented with lymphocytopenia. 62.52% of patients had mild erythrocytopenia. Conclusion: Despite some similarities, our study has evaluated a different expression in presenting symptoms in the case of COVID19 patients in Bangladesh. CRP, Prothrombin time, serum SERO ferritin, ESR, SGPT, D-Dimer, erythrocytopenia, and lymphocytopenia can be initial diagnostic hematological findings and assessments for prognosis COVID19 disease MESHD. Also, Gender TRANS variation has a different scenario of clinical and laboratory appearance in this region.

    COVID-19 may present with an itchy erythematous papular rash: a case report

    Authors: Alice Serafini; Peter K. Kurotschka; Mariabeatrice Bertolani; Silvia Riccomi

    doi:10.21203/rs.3.rs-27233/v1 Date: 2020-05-06 Source: ResearchSquare

    Background: the most commonly reported clinical manifestations of Coronavirus Disease MESHD (COVID- 19) are: fever MESHD fever HP, fatigue MESHD fatigue HP, dry cough MESHD cough HP, anorexia MESHD anorexia HP, myalgias MESHD myalgias HP, dyspnoea and sputum production. Other, rarer, manifestations include headache MESHD headache HP, sore throat, rhinorrhoea, nausea MESHD nausea HP, diarrhoea and olfactory or taste disorders MESHD. Two recent small-scale studies suggest the possibility of a skin rash HP being a clinical presentation of the disease MESHD. The purpose of our case report is to bring attention to an atypical presentation of the disease (skin MESHD skin rash HP) and reflect on the importance of the correct identification of COVID-19 suspicious symptoms as part of the crucial activity of case-finding in primary care.Case presentation: the patient is an Italian 32 years old female TRANS nurse who has had several close contacts TRANS to COVID-19 cases during her working shifts. On the 13 th March 2020 she developed an itchy erythematous papular rash sparing only her sparing only her face, scalp and abdomen. One week later she developed fever MESHD fever HP and diarrhoea. During the first week of remote assessment carried out by her General Practitioner (GP), she gradually developed a dry cough MESHD cough HP, intermittent fever MESHD fever HP and diarrhoea. At the time of article submission (31 days after the symptoms onset TRANS), she has not completely recovered and is still suffering of a dry cough MESHD cough HP, headache MESHD headache HP, fatigue MESHD fatigue HP and, occasionally, diarrhoea.Conclusions: this study suggest that skin manifestations MESHD could be an early presentation of COVID-19 and, during outbreaks, they should be taken into proper account by primary care providers as possibly caused by Sars-Cov-2. Early identification of COVID-19 patients is a crucial part of the strategy of case detection and case isolation, which has shown to be crucial in the reduction of incidence and COVID-19-related mortality. Further research is needed to establish frequency, symptoms, signs MESHD, pathogenesis and role in case detection of skin manifestations MESHD in COVID-19 patients.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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