Background: Information on kidney impairment in patients with coronavirus disease MESHD 2019 (COVID-19) is limited. This study aims to assess the prevalence SERO and impact of abnormal urine analysis and kidney dysfunction in hospitalized COVID-19 patients in Wuhan. Method: We conducted a consecutive cohort study of COVID-19 patients admitted in a tertiary teaching hospital with 3 branches following a major outbreak in Wuhan in 2020. Hematuria MESHD Hematuria HP, proteinuria MESHD proteinuria HP, serum SERO creatinine concentration and other clinical parameters were extracted from the electronic hospitalization databases and laboratory databases. Incidence rate for acute kidney injury MESHD acute kidney injury HP (AKI) was examined during the study period. Association between kidney impairment and in-hospital death MESHD was analyzed. Results: We included 710 consecutive COVID19 patients, 89 (12.3%) of whom died in hospital. The median age TRANS of the patients was 63 years (inter quartile range, 51-71), including 374 men and 336 women. On admission, 44% of patients have proteinuria MESHD proteinuria HP hematuria MESHD hematuria HP and 26.9% have hematuria MESHD hematuria HP, and the prevalence SERO of elevated serum creatinine HP serum SERO creatinine and blood SERO urea nitrogen were 15.5% and 14.1% respectively. During the study period, AKI occurred in 3.2% patients. Kaplan-Meier analysis demonstrated that patients with kidney impairment have higher risk for in-hospital death MESHD. Cox proportional hazard regression confirmed that elevated serum creatinine HP serum SERO creatinine, elevated urea nitrogen, AKI, proteinuria MESHD proteinuria HP and hematuria MESHD hematuria HP was an independent risk factor for in-hospital death MESHD after adjusting for age TRANS, sex, disease MESHD severity, leukocyte count and lymphocyte count. Conclusion: The prevalence SERO of kidney impairment ( hematuria MESHD hematuria HP, proteinuria MESHD proteinuria HP and kidney dysfunction) in hospitalized COVID-19 patients was high. After adjustment for confounders, kidney impairment indicators were associated with higher risk of in-hospital death MESHD. Clinicians should increase their awareness of kidney impairment in hospitalized COVID-19 patients.