Objective: To analyze the clinical characteristics of patients with novel coronavirus pneumonia MESHD pneumonia HP in Kunming City, and to study the correlation between nutritional status and immune function. Methods: Clinical data of 36 patients with novel coronavirus pneumonia MESHD pneumonia HP in isolation area of Kunming Third People's Hospital from January 31 to February 15, 2020 were collected, and the basic situation, clinical characteristics, laboratory examination and CT imaging characteristics were analyzed. Serum SERO albumin (ALB), prealbumin (PAB), hypersensitive c-reactive protein (hs-crp), CD3T cells, CD4T cells, CD8T cells and normal control group were analyzed. A simple linear regression analysis of the relationship between proalbumin and T cell subpopulation counts in the blood SERO of patients. Results: (1) The patients with new coronavirus pneumonia MESHD pneumonia HP in Kunming were mainly of common type. (2) 50% of the patients' first symptoms were fever MESHD fever HP and cough MESHD cough HP; (3) The total number of white blood SERO cells in peripheral blood SERO was normal or decreased in 23 cases (79%), and the lymphocyte count decreased in 5 cases (13.89%), without anemia MESHD anemia HP. Hypersensitive c-reactive protein increased in 19 (52.78%) cases, and procalcitonin increased in 1 case. Albumin decreased in 5 cases (13.89%), proalbumin decreased in 15 cases (41.67%), alanine transaminase increased slightly in 4 cases (11.11%), alanine transaminase increased slightly in 4 cases (11.11%), total bilirubin increased HP slightly in 11 cases (30.56%), and renal function and blood SERO coagulation were normal. Absolute value of CD3+T cells is with a decrease in 21 cases (58.3%), CD4+T in 28 cases (77.8%), CD8+T in 17 cases (47.2%), and CD4+/ CD8+ inverse in 6 cases (16.7%). (4) The prealbumin, CD3 T cells, CD4 T cells and CD8 T cells in the new coronavirus pneumonia MESHD pneumonia HP group were significantly lower than those in the normal control group, and the hypersensitive c-reactive protein was higher than that in the normal control group. (5) The levels of PAB in the serum SERO of the patients were linearly correlated with hs-crp, CD3 T cells, CD4 T cells and CD8 T cells, and the correlation coefficients were -0.474, 0.558, 0.467 and 0.613, respectively, showing statistical differences. Conclusion: The clinical characteristics of the novel coronavirus pneumonia MESHD pneumonia HP in Kunming are different from those in Wuhan. The changes of serum SERO proalbumin and T cell subsets are relatively obvious. Changes in serum SERO proalbumin may contribute to the early warning of novel coronavirus pneumonia MESHD pneumonia HP. The nutritional status of patients with common and mild pneumonia MESHD pneumonia HP should be considered.