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MeSH Disease

Human Phenotype

Transmission

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    Acute transverse myelitis MESHD myelitis HP in a HIV-positive patient with COVID-19

    Authors: Vitalie Lisnic; Victor Nemtan; Evghenia Hacina; Galina Topciu; Elena Manole; Majda M. Thurnher; Rüdiger von Kummer

    doi:10.21203/rs.3.rs-50901/v1 Date: 2020-07-29 Source: ResearchSquare

    Immunocompromised status keeps on being a challenge for a neurologist, especially in the context of the coronavirus disease MESHD – 19 (COVID-19) pandemic. We report a clinical case of a human- immunodeficiency HP virus (HIV) - positive patient who developed an acute transverse myelitis MESHD myelitis HP. Magnetic Resonance Imaging (MRI) examination showed longitudinally extensive spinal cord abnormality HP, and laboratory tests confirmed SARS-CoV-2 infection MESHD. The patient responded to methylprednisolone pulse therapy and therapeutic plasma SERO exchange. No cases of HIV-positive patients with myelitis MESHD myelitis HP and COVID-19 has been reported yet.

    Neurological Complications of COVID-19: A Systematic Review of Literature

    Authors: Shitiz Sriwastava; Samiksha Srivastava; Saurabh Kataria; Violina Melnic; Amelia Adcock; Zubeda Sheikh

    doi:10.21203/rs.3.rs-35507/v1 Date: 2020-06-14 Source: ResearchSquare

    Background: To study the nature and frequency of occurrence of “significant” neurological complications in coronavirus disease MESHD-2019 (COVID-19) via a systematic review of the literature.Methods: We screened all articles resulting from a search of PubMed, Cochrane, Google Scholar and Scopus, using the keywords "COVID-19 and CNS", "SARS-CoV-2 and CNS”, “COVID-19 and neurological manifestation”, “SARS2 and neurological manifestation” and “COVID-19 and Brain” looking for reports of significant neurological manifestations that would potentially have an impact on the outcome.Results: Twenty-six articles met the inclusion criteria. The significant neurological diagnoses reported were stroke MESHD stroke HP, Guillain Barre Syndrome MESHD (GBS) and its variants, encephalitis MESHD encephalitis HP, seizures MESHD seizures HP, acute hemorrhagic necrotizing encephalopathy, acute HP acute disseminated encephalomyelitis MESHD (ADEM) and transverse myelitis MESHD myelitis HP. Although stroke MESHD stroke HP, predominantly ischemic, was observed in ~ 6% of COVID-19 patients from Wuhan, China, mortality in this cohort was 38%. Of the 24 pooled patients with reports of etiology, 17 had large vessel occlusions. GBS occurred in 5/1200 (0.4%) of the COVID-19 cohort from Italy. One of the six reported encephalitis MESHD encephalitis HP cases, the ADEM case and the report of transverse myelitis MESHD myelitis HP do not have data for conclusive diagnosis.Conclusion: The most frequent significant neurological association with COVID-19 is stroke MESHD stroke HP, predominantly ischemic. In a cohort from Wuhan, China, this was as frequent as ~ 6%, with a 38% mortality. Most common reported etiology is large vessel occlusion. Other reported significant neurological complications are GBS/variants, encephalitis MESHD encephalitis HP, seizures MESHD seizures HP and acute hemorrhagic necrotizing encephalopathy HP. The reports of ADEM and transverse myelitis MESHD myelitis HP lacked diagnostically conclusive data.

    Neurological Manifestations and Complications of COVID-19: A Literature Review

    Authors: Imran Ahmad; Farooq Azam Rathore

    id:10.20944/preprints202004.0453.v1 Date: 2020-04-25 Source: Preprints.org

    The Coronavirus disease MESHD due to SARS-CoV-2 emerged in Wuhan city, China in December 2019 and rapidly spread more than 200 countries as a global health pandemic. There are more 3 million confirmed cases TRANS and around 207,000 fatalities. The primary manifestation is respiratory and cardiac but neurological manifestations are being reported in the literature as case reports and case series. The most common reported symptoms to include headache MESHD headache HP and dizziness MESHD followed by encephalopathy HP and delirium MESHD delirium HP. Among the complications noted are Cerebrovascular accident, Guillian barre syndrome MESHD, acute transverse myelitis MESHD myelitis HP, and acute encephalitis MESHD encephalitis HP. The most common peripheral manifestation was hyposmia HP. It is further noted that sometimes the neurological manifestations can precede the typical features like fever MESHD fever HP and cough MESHD cough HP and later on typical manifestations develop in these patients. Hence a high index of suspicion is required for timely diagnosis and isolation of cases to prevent the spread in neurology wards. We present a narrative review of the neurological manifestations and complications of COVID-19. Our aim is to update the neurologists and physicians working with suspected cases of COVID-19 about the possible neurological presentations and the probable neurological complications resulting from this novel virus infection MESHD.

    Acute myelitis MESHD myelitis HP after SARS-CoV-2 infection MESHD: a case report.

    Authors: Kang Zhao; Jucun Huang; Dan Dai; Yuwei Feng; Liming Liu; Shuke Nie

    doi:10.1101/2020.03.16.20035105 Date: 2020-03-18 Source: medRxiv

    We report a case of acute myelitis MESHD myelitis HP in a patient infected with severe acute respiratory syndrome MESHD coronavirus 2 (SARS-CoV-2). A 66-year-old man with coronavirus disease MESHD 2019 was admitted with acute flaccid paralysis MESHD paralysis HP of the bilateral lower limbs and urinary and bowel incontinence HP. All serum SERO microbiological test results were negative, except for SARS-CoV-2 nucleic acid testing. Clinical findings indicated post-infectious acute myelitis MESHD myelitis HP. He received treatment containing ganciclovir, lopinavir/ritonavir, moxifloxacin, dexamethasone, human immunoglobulin, and mecobalamin. With a diagnosis of post-infectious acute myelitis MESHD myelitis HP and comprehensive treatment, paralysis MESHD paralysis HP of the bilateral lower extremities ameliorated. After two negative novel coronavirus RNA nasopharyngeal swab tests, he was discharged and transferred to a designated hospital for isolation and rehabilitation therapy.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).

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MeSH Disease
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