Background: Pain MESHD Pain HP management services and support programs have been closed during pandemic. Self-management options, particularly for chronic pain MESHD chronic pain HP, is required which can be undertaken at ones own convenience and without leaving home. Objectives: To evaluate the impact of tele-yoga therapy on patients suffering with chronic pain MESHD chronic pain HP reducing pain MESHD pain HP intensity, disability, anxiety HP and depression. Material and methods: In total 18 patients with different chronic pain MESHD chronic pain HP diagnosis were recruited to individual yoga Therapy sessions twice a week at home (tele-yoga) using a videoconference app. Each participant followed set of practices every day at home. Main outcome measures included pain MESHD pain HP intensity, pain MESHD pain HP disability, anxiety HP and depression scores. Data were collected at baseline and after 6-weeks of intervention. Results: There were significant improvement in pain MESHD pain HP intensity from Baseline to 6-weeks (P<0.001); also pain MESHD pain HP disability (P<0,001). Both scores of anxiety HP and depression reduced at the end of intervention period (P<0,001; P<0,001). Conclusions: Pilot results suggest that tele-yoga therapy may be an effective tool to self-manage chronic pain MESHD chronic pain HP and related functional and psychological impacts. Further larger studies, randomized, controlled trials are needed to confirm the preliminary outcome.