Corpus overview


MeSH Disease

Human Phenotype

Wheezing (2)

Fatigue (2)

Cough (1)

Fever (1)

Pneumonia (1)



There are no seroprevalence terms in the subcorpus

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    Incidental 18F-FDG PET/CT finding of COVID-1 pneumonia MESHD pneumonia HP in asymptomatic TRANS patient diagnosed with lung abscess MESHD lung abscess HP metastasis

    Authors: Antoni Mestre-Fusco; Mònica Velasco-Nuño; Montserrat Negre-Busó; Núria Ferran; Sergi Juanpere; Antoni Rubió

    doi:10.21203/ Date: 2020-05-20 Source: ResearchSquare

    A 66-year-old male TRANS patient, with chronic respiratory disease MESHD and right colon resection in March 2017 for colon low-grade adenocarcinoma MESHD was assessed for recurrence MESHD suggested by elevated levels of tumor marker and no evidence of oncological disease MESHD by CT scan. 18F-FDG PET/CT showed bilateral multiple peripheral FDG-avid foci that matched with a peripheral predominant ground-glass opacities (GGOs) observed in lower lobes and multiple FDG-positive enlarged lymph nodes were also identified in the mediastinum. Patient was hospitalized in March 14th 2020, one day after PET/CT scan, with cough MESHD cough HP, wheezing HP and fever MESHD fever HP, and was treated with anti-inflammatory drugs. A first SARS-CoV-2 RT-PCR in March 15th resulted as negative and patient was treated with antibiotic therapy lead to an improvement of respiratory symptoms. PET/CT scan was interpreted as a pneumonia MESHD pneumonia HP foci. A deteriorating patient condition was observed, with respiratory symptomatology progression, fatigue MESHD fatigue HP and D-Dimer elevation and a new RT-PCR resulted positive. A week after PET/CT scan, hospitalization in intensive care unit was necessary for rapidly disease progression MESHD and severe respiratory distress HP syndrome MESHD and patient died four days later.

    Clinical characteristics and outcome of influenza virus infection MESHD among adults TRANS hospitalized with severe COVID-19: A retrospective cohort study from Wuhan, China

    Authors: Xunliang Tong; Xiaomao Xu; Guoyue Lv; He Wang; Anqi Cheng; Dingyi Wang; Yanming Li

    doi:10.21203/ Date: 2020-05-08 Source: ResearchSquare

    Background Coronavirus disease MESHD 2019 (COVID-19) is an emerging infection MESHD disease MESHD that rapidly spreads worldwide. Clinical features and outcomes of severe COVID-19 patients with influenza virus IgM positive during the influenza season need to be described.Methods Retrospective cohort study of 140 patients with severe COVID-19 hospitalized in designated wards of Sino-French New City Branch of Tongji Hospital between Feb 8th and March 15th in Wuhan, Hubei province, China. The demographic, clinical feature, laboratory, treatment and outcome were collected and analyzed.Results Of 140 severe COVID-19 hospitalized patients, 73 patients were with median age TRANS of 66 years old with identification of influenza virus IgM-positive and 67 patients were with median age TRANS of 62 years old in influenza virus IgM-negative group. Nearly half of severe COVID-19 patients in this research are male TRANS. Majority of the severe COVID-19 patients had chronic underlying conditions. Wheeze HP was the clinical feature of severe COVID-19 patients with influenza IgM-positive (26.4% vs 9.0%, P = 0.008). On contrary, fatigue MESHD fatigue HP or myalgia MESHD myalgia HP was the feature of the COVID-19 patients without IgM-positive (38.4% vs 58.2%, P = 0.019). In laboratory examination, increased levels of ferritin and prolonging APTT were showed in severe COVID-19 patients without influenza IgM-positive compared with patients in the other group with significant differences. Death MESHD rate in the group of severe COVID-19 patients with influenza IgM-positive is higher than it is in other group with significant differences (14.9% vs 4.1%, P = 0.040). In univariate regression analysis, several factors were associated with higher risk of death MESHD, which included LDH, troponin, NT-proBNP, D-dimer, PT, APTT, lymphocytes, platelet and eGFR. However, influenza virus IgM positive was associated with lower risk of death MESHD. Multivariate Regression analysis showed that troponin and lymphocyte were independently associated with higher risk of death MESHD.Conclusion The characteristics of patients hospitalized with severe COVID-19 with identification of influenza virus IgM-positive were described. It hints proof of seasonal influenza which may overlap with COVID-19 and may cause a crisis we could confront in the future.

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MeSH Disease
Human Phenotype

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