Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Spinal Epidural Abscess MESHD Abscess HP in COVID-19 patients

    Authors: Giuseppe Talamonti; Davide Colistra; Francesco Crisà; Marco Cenzato; Pietro Giorgi; Giuseppe D'Aliberti

    doi:10.21203/rs.3.rs-38110/v1 Date: 2020-06-27 Source: ResearchSquare

    Objective: To report the peculiarities of spinal epidural abscess MESHD abscess HP in COVID-19 patients, because we observed an unusually high number of these patients following the outbreak of SARS-Corona Virus-2.Methods: We reviewed the clinical documentation of six consecutive COVID-19 patients with primary spinal epidural abscess HP that we had to surgically manage during a two-month period. These cases were analyzed for what concerns both the viral infection MESHD and the spinal abscess MESHD abscess HP.Results: Abscess was primary in all cases TRANS meaning that no evident infective source was found. Primary abscess HP represents the rarest form of spinal epidural abscess MESHD abscess HP, which is usually secondary to invasive procedures or spreading from adjacent infective sites, such as spondylodiscitis MESHD and generally occurs in patients with diabetes MESHD, obesity HP obesity MESHD, cancer MESHD, or other chronic disease MESHD. In all cases, there was mild lymphopenia HP lymphopenia MESHD but the spinal abscess HP occurred regardless the severity of the viral disease, the immunologic state, and the presence of bacteremia HP bacteremia MESHD. Obesity HP was the only risk factor and was reported just in two patients. All patients but one were hypertensive MESHD. The preferred localizations were cervical and thoracic, whereas the classic abscess HP generally occurs at lumbar level. No patient had history of pyogenic infection MESHD, even though previous asymptomatic TRANS bacterial contaminations were reported in three cases.Conclusion: We wonder about the concentration of this uncommon disease in a so short period. To our knowledge, cases of epidural spinal abscess MESHD abscess HP in COVID-19 patients have been not yet reported. Accordingly, we ignore if the SARS-Corona Virus-2 may really predispose to spinal epidural abscesses HP. However, we hypothesize that, in our patients, the spinal infection could have depended on the coexistence of an initially asymptomatic TRANS bacterial contamination. The well-known COVID-19-related endotheliitis might have created the conditions for retrograde bacterial invasion of the correspondent spinal epidural space. Anyway, the spinal epidural abscess MESHD abscess HP carries significantly high morbidity and mortality. It is difficult to diagnose, especially in compromised COVID-19 patients but it should be kept in mind because early diagnosis and treatment are crucial.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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