Corpus overview


MeSH Disease

Human Phenotype



There are no seroprevalence terms in the subcorpus

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    Previous and active tuberculosis MESHD in COVID-19 patients increases risk of death MESHD and prolongs recovery

    Authors: Karla Therese L. Sy; Nel Jason Ladiao Haw; Jhanna Uy

    doi:10.1101/2020.07.22.20154575 Date: 2020-07-26 Source: medRxiv

    Background: There is a growing literature on the association of SARS-CoV-2 and other chronic conditions, such as noncommunicable diseases MESHD. However, little is known about the impact of coinfection MESHD with tuberculosis MESHD. We aimed to compare the risk of death MESHD and recovery, as well as time-to- death MESHD and time-to-recovery TRANS, in COVID-19 patients with and without TB. Methods: We created a 4:1 propensity score matched sample of COVID-19 patients without and with tuberculosis MESHD, using COVID-19 surveillance data in the Philippines. We conducted a longitudinal cohort analysis of matched COVID-19 patients as of May 17, 2020, following them until June 15, 2020. The primary analysis estimated the risk ratios of death MESHD and recovery in patients with and without tuberculosis MESHD. Kaplan-Meier curves described time-to- death MESHD and time-to-recovery TRANS stratified by tuberculosis MESHD status, and differences in survival were assessed using the Wilcoxon test. Results: The risk of death MESHD in COVID-19 patients with tuberculosis MESHD was 2.17 times higher than in those without (95% CI: 1.40-3.37). The risk of recovery in COVID-19 patients with tuberculosis MESHD was 25% lower than in those without (RR=0.75, 95% CI 0.63-0.91). Similarly, time-to- death MESHD was significantly shorter (p=0.0031) and time-to-recovery TRANS significantly longer in patients with tuberculosis MESHD (p=0.0046). Conclusions: Our findings show that coinfection MESHD with tuberculosis MESHD increased morbidity and mortality in COVID-19 patients. Our findings highlight the need to prioritize routine and testing services for tuberculosis MESHD, although health systems are disrupted by the heavy burden of the SARS-CoV-2 pandemic.

    Survival in adult TRANS inpatients with COVID-19

    Authors: Efren Murillo-Zamora; CARLOS M HERNANDEZ-SUAREZ

    doi:10.1101/2020.05.25.20110684 Date: 2020-05-26 Source: medRxiv

    We conducted a nationwide and retrospective cohort study to assess the survival experience and determining factors in adult TRANS inpatients with laboratory-confirmed COVID-19. Data from 5,393 individuals were analyzed using the Kaplan-Meier method and a multivariate Cox proportional hazard regression model was fitted. The 7-day survival was 0.822 and went to 0.482, 0.280, and 0.145 on days 15, 21, and 30 of hospital stay, respectively. In the multiple analysis, factors associated with an increased risk of dying were: male TRANS gender TRANS, age TRANS, longer disease MESHD evolution before hospital entry, exposure to mechanical ventilator support, and personal history of chronic noncommunicable diseases MESHD (namely obesity MESHD obesity HP, type-2 diabetes mellitus MESHD diabetes mellitus HP, and chronic kidney disease HP kidney disease MESHD). To the best of our knowledge, this is the first study analyzing the survival probability in a large subset of Latin-American adults TRANS with COVID-19 and our results contribute to achieving a better understanding of disease MESHD evolution.

    COVID-19 Pandemic: Is Chronic Inflammation MESHD a Major Cause of Death MESHD?

    Authors: Albina Tskhay; Alena Yezhova; Kenneth Alibek

    doi:10.1101/2020.05.12.20099572 Date: 2020-05-19 Source: medRxiv

    Abstract Background. Today humanity is facing another infectious threat: a newly emerging virus SARS-CoV-2 causing COVID-19. It was already described that COVID-19 mortality among elderly TRANS people and people with such underlying conditions as obesity MESHD obesity HP, cardiovascular diseases MESHD, cancer, chronic respiratory diseases MESHD, and diabetes s increased. Dysregulation of the immune HP responses vital for antiviral defense, which are typical for chronic inflammation MESHD, led us to a hypothesis that chronic inflammation MESHD is the main risk factor for increased susceptibility and mortality from COVID-19. Method. Based on the available information for 126 countries, statistical analysis to find out whether the difference in incidence and mortality within countries can be explained by the existing chronic inflammation MESHD among the countries population, was conducted. Results. A positive correlation between the percentage of people dying from chronic noncommunicable diseases MESHD and COVID-19 incidence (p<0.001) and mortality (p<0.001) within countries. Conclusion. The problem of COVID-19-caused high mortality rate may be a consequence of the high number of people having chronic low-grade inflammation MESHD as a precondition, and thus, one of the potential ways to reduce risk of morbidity and mortality is to focus on this widespread health problem, mainly occurring in developed countries and to take corresponding diagnostic, preventative, and treatment measures.

    The Main Risk Factors for the Number of Serious or Critical Cases of Covid-19: How is the Health of Brazilians?

    Authors: Haniel Fernandes

    id:10.20944/preprints202005.0143.v1 Date: 2020-05-08 Source:

    Chronic noncommunicable diseases MESHD (CNCDs) have been a major public health concern worldwide, especially diabetes, cardiovascular disease MESHD disease, chronic obstructive pulmonary HP chronic obstructive pulmonary disease MESHD, hypertension MESHD hypertension HP, in addition to obesity MESHD obesity HP, which is even more worrying when the subject involves the covid-19 pandemic, because such incidences correlate with the need for intensive care units, including the possibility of death MESHD of the patient. Therefore, for countries with the highest numbers of critical cases, it is important to assess the incidence of these diseases MESHD to guide the public that most needs guidance on public policies for social isolation.

    Covid-19 Situation in Bangladesh

    Authors: Abdul Kader Mohiuddin

    id:10.20944/preprints202005.0094.v1 Date: 2020-05-06 Source:

    COVID-19 has affected 210 countries around the world, killed more than 240,000 and infected more than 3.4 million. Bangladesh, a South Asian low-middle-income economy, has experienced a demographic and epidemiological transition with rapid urbanization and a gradual increase in life expectancy. It is the seventh most populous country in the world and population of the country is expected to be nearly double by 2050. The increasing burden of noncommunicable diseases MESHD in Bangladesh can be attributable to rapid urbanization and nearly 50% of all slum dwellers of the country live in Dhaka division. In 2017, National Rapid Response Team of IEDCR investigated 26 incidents of disease MESHD outbreak. The joint survey of the Power and Participation Research Centre and BRAC Institute of Governance and Development reveals that per capita daily income of urban slum and rural poor drops by 80% due to present countrywide shutdown enforced by the government to halt the spread of Covid-19. 40%-50% of these population took loans to meet the daily expenses.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from and is updated on a daily basis (7am CET/CEST).



MeSH Disease
Human Phenotype

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