Corpus overview


MeSH Disease

Human Phenotype

There are no HP terms in the subcorpus



There are no seroprevalence terms in the subcorpus

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    Risk of Human-to-Wildlife Transmission TRANS of SARS-CoV-2

    Authors: Sophie Gryseels; Luc De Bruyn; Ralf Gyselings; Sébastien Calvignac-Spencer; Fabian Leendertz; Herwig Leirs

    id:10.20944/preprints202005.0141.v1 Date: 2020-05-08 Source:

    It has been a long time since the world has experienced a pandemic with such a rapid devastating impact as the current COVID-19 pandemic. The causative agent, the Severe Acute Respiratory Syndrome MESHD coronavirus 2 (SARS-CoV-2) is further unusual in that it appears capable of infecting many different mammal species. As a significant proportion of people worldwide are infected with SARS-CoV-2 and may spread the infection MESHD unknowingly before symptoms occur or without any symptoms ever occurring, there is a non-negligible risk of humans spreading SARS-CoV-2 to wildlife, in particular mammals. Because of SARS-CoV-2’s evolutionary origins in bats and reports of humans transmitting the virus to pets and zoo animals, regulations for prevention of human-to-animal transmission TRANS have so far focused mostly on these animal groups. Here, we summarize recent studies and reports that show that a wide range of distantly related mammals are likely susceptible to SARS-CoV-2 and that susceptibility or resistance to the virus is in general not predictable, or only to some extent, by phylogenetic proximity to known susceptible or resistant hosts. In the absence of solid evidence on the SARS-CoV-2 susceptibility/resistance for each of the >5,500 mammal species, we argue that sanitary precautions should be taken when interacting with any mammal species in the wild. Preventing human-to-wildlife SARS-CoV-2 transmission TRANS is important for protecting these (sometimes endangered) animals from disease MESHD, but also to avoid establishment of novel SARS-CoV-2 reservoirs in wild animals. The risk of repeated re- infection MESHD of humans from such a wildlife reservoir could severely hamper SARS-CoV-2 control efforts. For wildlife fieldworkers interacting directly or indirectly with mammals, we recommend sanitary precautions such as physical distancing, wearing face masks and gloves, and frequent decontamination, which are very similar to regulations currently imposed to prevent transmission TRANS among humans.

    Clinical, Molecular and Epidemiological Characterization of the SARS-CoV2 Virus and the Coronavirus Disease MESHD 2019 (COVID-19): A Comprehensive Literature Review

    Authors: Esteban Ortiz-Prado; Katherine Simbaña-Rivera; Lenin Gomez-Barreno; Mario Rubio-Neira; Linda P. Guaman; Nikolaos Kyriakidis; Claire Muslin; Ana Maria Gomez-Jaramillo; Carlos Barba; Domenica Cevallos; Hugo Sanchez-San Miguel; Luis Unigarro; Rasa Zalakeviciute; Naomi Gadian; Andrés López-Cortés

    id:10.20944/preprints202004.0283.v1 Date: 2020-04-16 Source:

    Coronaviruses are an extensive family of viruses that can cause disease in both animals MESHD and humans. The current classification of coronaviruses recognizes 39 species in 27 subgenera that belong to the family Coronaviridae. From those, at least seven coronaviruses are known to cause respiratory infections MESHD in humans. Four of these viruses can cause common cold MESHD-like symptoms, while others that infect animals can evolve and become infectious to humans. Three recent examples of this viral jumps include SARS CoV, MERS-CoV and SARS CoV-2 virus. They are responsible for causing severe acute respiratory syndrome MESHD (SARS), Middle East respiratory syndrome MESHD (MERS) and the most recently discovered coronavirus disease MESHD during 2019 (COVID-19).COVID-19, a respiratory disease MESHD caused by the SARS-CoV-2 virus, was declared a pandemic by the World Health Organization (WHO) on 11 March 2020. The rapid spread of the disease TRANS disease MESHD has taken the scientific and medical community by surprise. Latest figures from 14 April 2020 show more than 2 million people had been infected with the virus, causing more than 120,000 deaths MESHD in over 210 countries worldwide. The large amount of information we receive every day concerning this new disease MESHD is so abundant and dynamic that medical staff, health authorities, academics and the media are not able to keep up with this new pandemic. In order to offer a clear insight of the extensive literature available, we have conducted a comprehensive literature review of the SARS CoV-2 Virus and the Coronavirus Diseases MESHD 2019 (COVID-19).

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from and is updated on a daily basis (7am CET/CEST).



MeSH Disease
Human Phenotype

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