Corpus overview


MeSH Disease

Human Phenotype

Ataxia (3)

Falls (1)

Headache (1)

Hyposmia (1)

Hypertension (1)



There are no seroprevalence terms in the subcorpus

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    Mental health of spinocerebellar ataxia MESHD ataxia HP patients during COVID-19 pandemic: a cross-sectional study

    Authors: Yiqing Gong; Zhao Chen; Mingjie Liu; Linlin Wan; Chunrong Wang; Huirong Peng; Yuting Shi; Yun Peng; Kun Xia; Rong Qiu; Beisha Tang; Hong Jiang

    doi:10.21203/ Date: 2020-07-07 Source: ResearchSquare

    COVID-19 is a global concern nowadays, and the psychological impact of the pandemic cannot be overlooked. People are under insurmountable pressure, which may lead to psychological problems such as anxiety HP and depression. The purpose of this study was to evaluate the mental health of spinocerebellar ataxia MESHD ataxia HP (SCA) patients during COVID-19 pandemic and to analyze its influencing factors. We conducted an online questionnaire survey among 307 SCA patients from China. The contents of the questionnaire included general information, the self-rating anxiety HP scale (SAS), the self-rating depression scale (SDS). The relevant influencing factors included COVID-19 risk factors, age TRANS, gender TRANS, BMI (body mass index), educational background, disease MESHD course, and score of the scale for the assessment and rating of ataxia MESHD ataxia HP (SARA). Results indicate the 307 SCA patients had an anxiety HP rate of 34.9%, along with a depression rate of 56.7%. Their SAS and SDS scores were significantly higher than those of the Chinese norm group (SAS: 45.8±10.1 vs. 37.2±12.6, P < 0.01; SDS: 55.1±12.2 vs. 41.9±10.6, P < 0.01). Risks of exposure to COVID-19, educational level, and disease MESHD course may be factors affecting mental health status. The existence of a positive correlation among the scores of SARA, SAS and SDS scale was demonstrated, the higher the SARA score, the higher the risk of anxiety HP and depression. Anxiety HP and depression were more prevalent in SCA patients compared with the normal population, and depression was more common than anxiety HP during this pandemic. More psychological attention should be paid to SCA patients during COVID-19 pandemic.

    Ataxia MESHD Ataxia HP as a presenting manifestation of COVID -19: Report of a single case

    Authors: Debaleena Mukherjee; Peyalee Sarkar; Souvik Dubey; Biman Kanti Ray; Alak Pandit; Durjoy Lahiri

    doi:10.1101/2020.05.24.20103648 Date: 2020-05-26 Source: medRxiv

    Even though various neurological presentations of COVID-19 have surfaced up, ataxia MESHD ataxia HP as a presenting feature has rarely been reported so far. We hereby describe a confirmed case TRANS of SARS-CoV-2 infection MESHD which not only presented with ataxia MESHD ataxia HP but also had delayed onset of typical respiratory features. This case represents an atypical manifestation of COVID-19.

    Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: a retrospective case series study

    Authors: Ling Mao; Mengdie Wang; Shanghai Chen; Quanwei He; Jiang Chang; Candong Hong; Yifan Zhou; David Wang; Yanan Li; Huijuan Jin; Bo Hu

    doi:10.1101/2020.02.22.20026500 Date: 2020-02-25 Source: medRxiv

    OBJECTIVE: To study the neurological manifestations of patients with coronavirus disease MESHD 2019 (COVID-19). DESIGN: Retrospective case series SETTING: Three designated COVID-19 care hospitals of the Union Hospital of Huazhong University of Science and Technology in Wuhan, China. PARTICIPANTS: Two hundred fourteen hospitalized patients with laboratory confirmed diagnosis of severe acute respiratory syndrome MESHD from coronavirus 2 (SARS-CoV-2) infection MESHD. Data were collected from 16 January 2020 to 19 February 2020. MAIN OUTCOME MEASURES: Clinical data were extracted from electronic medical records and reviewed by a trained team of physicians. Neurological symptoms fall HP into three categories: central nervous system (CNS) symptoms or diseases MESHD ( headache MESHD headache HP, dizziness MESHD, impaired consciousness, ataxia MESHD ataxia HP, acute cerebrovascular disease MESHD, and epilepsy MESHD), peripheral nervous system (PNS) symptoms (hypogeusia, hyposmia HP, hypopsia, and neuralgia MESHD), and skeletal muscular symptoms. Data of all neurological symptoms were checked by two trained neurologists. RESULTS: Of 214 patients studied, 88 (41.1%) were severe and 126 (58.9%) were non-severe patients. Compared with non-severe patients, severe patients were older (58.7 {+/-} 15.0 years vs 48.9 {+/-} 14.7 years), had more underlying disorders (42 [47.7%] vs 41 [32.5%]), especially hypertension MESHD hypertension HP (32 [36.4%] vs 19 [15.1%]), and showed less typical symptoms such as fever MESHD fever HP (40 [45.5%] vs 92 [73%]) and cough MESHD cough HP (30 [34.1%] vs 77 [61.1%]). Seventy-eight (36.4%) patients had neurologic manifestations MESHD. More severe patients were likely to have neurologic symptoms (40 [45.5%] vs 38 [30.2%]), such as acute cerebrovascular diseases MESHD (5 [5.7%] vs 1 [0.8%]), impaired consciousness (13 [14.8%] vs 3 [2.4%]) and skeletal muscle injury (17 [19.3%] vs 6 [4.8%]). CONCLUSION: Compared with non-severe patients with COVID-19, severe patients commonly had neurologic symptoms manifested as acute cerebrovascular diseases MESHD, consciousness impairment and skeletal muscle symptoms.

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MeSH Disease
Human Phenotype

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