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MeSH Disease

Human Phenotype

Transmission

Seroprevalence
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    SARS-COV-2 infection MESHD during pregnancy, a risk factor for eclampsia HP eclampsia MESHD or neurological manifestations of COVID-19? Case report.

    Authors: Alejandro Garcia Rodriguez; Sergio Marcos Contreras; Santiago Manuel Fernandez Manovel; Jose Miguel Marcos Vidal; Fernando Diez Buron; Camino Fernandez Fernandez; Maria del Carmen Riveira Gonzalez

    doi:10.21203/rs.3.rs-40372/v1 Date: 2020-07-06 Source: ResearchSquare

    Background: There are no published cases of tonic-clonic seizures MESHD seizures HP and posterior bilateral blindness MESHD blindness HP during pregnancy and SARS-COV-2 infection MESHD. We do not just face new and unknown manifestations, but also how different patients groups are affected by SARS-Cov-2 infection MESHD, like pregnant women. COVID-19, preeclampsia HP, eclampsia HP eclampsia MESHD and posterior reversible leukoencephalopathy HP leukoencephalopathy MESHD share endothelium damage and similar pathophysiology. Case presentation: We present a case of a 35 years old pregnant woman, who comes to our hospital because of tonic-clonic seizures MESHD seizures HP at home and SARS-COV-2 infection MESHD. After Caesarean section, we initiate antihypertensive treatment with labetalol, amlodipine and captopril. Few hour after C-section, she develops blindness HP blindness MESHD with total recuperation after 72 hours, normal brain CT scan and normal CT angiography. She had normal pregnancy control and no other symptoms before tonic-clonic seizures MESHD seizures HP development. Conclusion: SARS-COV-2 infection MESHD could promote brain endothelial damage and facilitate neurological complications during pregnancy.

    Who is dying from Covid-19 in the United Kingdom? A review of cremation authorisations from a single South Wales' crematorium.

    Authors: Roland L. Salmon; Stephen P. Monaghan

    doi:10.1101/2020.07.01.20136317 Date: 2020-07-06 Source: medRxiv

    Abstract Background: Covid 19 is pandemic in the UK. To date only studies in the UK on hospital deaths have been published in the peer reviewed literature. Legal MESHD requirements for cremation in England and Wales require the collection of information that can be used to improve understanding of Covid 19 deaths in both hospital and community settings. Aim: To document demographic and clinical characteristics, including likely place of infection MESHD, of individuals dying of Covid 19 to inform public health policy Design: A comprehensive case series of deaths from Covid 19 between 6 April and 30 May. Setting: A crematorium in South Wales Participants: Individuals for whom an application was made for cremation. Main outcome measures: Age TRANS, sex, date and place of death MESHD, occupation, comorbidities, where infection acquired. Results: Of 752 cremations, 215(28.6%) were Covid-19 of which 115 (53.5%) were male TRANS and 100 (46.5%) female TRANS. The median age TRANS was 82 years, with the youngest patient being 47 years and the oldest 103 years. Over half the deaths (121/215: 56.3%) were over 80 years. Males TRANS odds of dying in hospital, rather than the community were 1.96 times that of females TRANS (95% Confidence Intervals (CI) 1.03 -3.74, p=0.054) despite being of similar age TRANS and having a similar number of comorbidities. Only 21(9.8%) of 215 patients had no comorbidities recorded. Patients dying in nursing homes were significantly older than those dying in hospital(median 88y (IQ range 82-93y) v 80y (IQ range 71-87y): p<0.0001). Patients dying in hospital had significantly more comorbidities than those dying in nursing homes (median 2: IQ range 1-3 v. 1: IQ range 1-2: p <0.001). Conclusions: In a representative series, comprising both hospital and community deaths, persons over 80 with an average 2 comorbidities predominated. Although men and women were represented in similar proportions, men were more likely to die in hospital. Over half the infections were acquired in either hospitals or nursing and residential homes with implications for the management of the pandemic, historically and in the future.

    Electrocardiographic findings of methanol toxicity MESHD: A cross-sectional study on 356 cases in Iran

    Authors: Mohammad Hossein Nikoo; Alireza Arjangzadeh; Maryam Pakfetrat; Shahrokh Sadeghi Boogar; Vahid Mohammadkarimi; Vahid Reza Ostovan; Zohre Khodamoradi; Jamshid Roozbeh; Mohammadreza Khalili; Farnaz Kamali Haghighi Shirazi; Paryia Kouhi; Seyyed Taghi Heydari

    doi:10.21203/rs.3.rs-34297/v2 Date: 2020-06-08 Source: ResearchSquare

    Background: Methanol is widely used in industry; however, methanol poisoning is not common. In this regard, a number of outbreaks have been recently reported due to inappropriate processing of alcoholic beverages. Shiraz, a city located in the southern part of Iran, faced one of such outbreaks in 2020 during COVID-19 pandemic. There is no sufficient literature on the electrocardiographic findings in methanol toxicity MESHD. This study aimed to address this gap in the literature.Method: A total of 356 cases with methanol toxicity MESHD referred to Shiraz University of Medical Science Tertiary Hospitals (Faghihi and Namazi) in March and April, 2020. The clinical findings of blindness HP blindness MESHD and impaired level of consciousness, lab data such as arterial blood SERO gas, electrolytes, and creatinine, and the most common findings from ECGs were collected. Results: The most common ECG findings were J point elevation (68.8%), presence of U wave (59.2%), QTc prolongation MESHD (53.2% in males TRANS and 28.6% in females TRANS), and fragmented QRS (33.7%). An outstanding finding in this study was the presence of myocardial infarction HP myocardial infarction MESHD in 5.3% of the cases. This finding, to the best of our knowledge, has only been reported in a few case reports. Brugada pattern (8.1%) and Osborn wave (3.7%) were the other interesting findings.In multivariate analysis, when confounding factors were adjusted, myocardial infarction HP myocardial infarction MESHD, atrioventricular conduction disturbances MESHD, sinus tachycardia HP sinus tachycardia MESHD, and the prolonged QTC>500 msecond were four independent factors correlated with methanol toxicity MESHD severity measured with arterial blood SERO PH on arterial blood SERO gas measurements, with odds ratios of 12.82, 4.46, 2.32 and 3.15 (P<0.05 for all) , respectively.Conclusion: Electrocardiographic variations during methanol intoxication are remarkable and well-correlated with poisoning severity. Myocardial infarction HP Myocardial infarction MESHD was an egregious and yet a common concerning finding in this sample, which need to be ruled out in methanol toxicity MESHD.

    Electrocardiographic findings of methanol toxicity MESHD: A cross-sectional study on 356 cases in Iran

    Authors: Mohammad Hossein Nikoo; Alireza Arjangzadeh; Maryam Pakfetrat; Shahrokh Sadeghi Boogar; Vahid Mohammadkarimi; Vahid Reza Ostovan; Zohre Khodamoradi; Jamshid Roozbeh; Mohammadreza Khalili; Farnaz Kamali Haghighi Shirazi; Paryia Kouhi; Seyyed Taghi Heydari

    doi:10.21203/rs.3.rs-34297/v3 Date: 2020-06-08 Source: ResearchSquare

    Background : Methanol is widely used in industry; however, methanol poisoning is not common. In this regard, a number of outbreaks have been recently reported due to inappropriate processing of alcoholic beverages. Shiraz, a city located in the southern part of Iran, faced one of such outbreaks in 2020 during COVID-19 pandemic. There is no sufficient literature on the electrocardiographic findings in methanol toxicity MESHD. This study aimed to address this gap in the literature. Method : A total of 356 cases with methanol toxicity MESHD referred to Shiraz University of Medical Science Tertiary Hospitals (Faghihi and Namazi) in March and April, 2020. The clinical findings of blindness HP blindness MESHD and impaired level of consciousness, lab data such as arterial blood SERO gas, electrolytes, and creatinine, and the most common findings from ECGs were collected. Results : The most common ECG findings were J point elevation (68.8%), presence of U wave (59.2%), QTc prolongation MESHD (53.2% in males TRANS and 28.6% in females TRANS), and fragmented QRS (33.7%). An outstanding finding in this study was the presence of myocardial infarction HP myocardial infarction MESHD in 5.3% of the cases. This finding, to the best of our knowledge, has only been reported in a few case reports. Brugada pattern (8.1%) and Osborn wave (3.7%) were the other interesting findings. In multivariate analysis, when confounding factors were adjusted, myocardial infarction HP myocardial infarction MESHD, atrioventricular conduction disturbances MESHD, sinus tachycardia HP sinus tachycardia MESHD, and the prolonged QTC>500 msecond were four independent factors correlated with methanol toxicity MESHD severity measured with arterial blood SERO PH on arterial blood SERO gas measurements, with odds ratios of 12.82, 4.46, 2.32 and 3.15 (P<0.05 for all) , respectively. Conclusion : Electrocardiographic variations during methanol intoxication are remarkable and well-correlated with poisoning severity. Myocardial infarction HP Myocardial infarction MESHD was an egregious and yet a common concerning finding in this sample, which need to be ruled out in methanol toxicity MESHD.

    Effectiveness of extracorporeal blood SERO purification (hemoadsorption) in patients with severe coronavirus disease MESHD 2019 (COVID-19) 

    Authors: Masoumeh Asgharpour; Hamed Mehdinezhad; Masoumeh Bayani; Mahmoud Sadeghi Haddad Zavareh; Seyed Hossein Hamidi; Roghayyeh Akbari; Reza Ghadimi; Ali Bijani; Simin Mouodi

    doi:10.21203/rs.3.rs-29229/v2 Date: 2020-05-14 Source: ResearchSquare

    BackgroundExtracorporeal blood SERO purification has been proposed as one of the therapeutic approaches in patients with c oronavirus infection, MESHD because of its beneficial impact on elimination of inflammatory cytokines. MethodsThis controlled trial has been conducted on critically ill COVID-19 patients admitted in the state hospital affiliated to Babol University of Medical Sciences, Iran who received different antiviral and antibacterial drugs, and different modalities of respiratory treatments and did not have positive clinical improvement. No randomization and blindness HP lindness MESHDwas considered. All of the participants underwent three sessions of resin-directed hemoperfusion using continuous renal replacement therapy with a mode of continuous venovenous hemofiltration (CVVH). ResultsFive men and five women with a mean age TRANS of 57.30±18.07 years have been enrolled in the study; and six of them have improved after the intervention. Peripheral capillary oxygen saturation (SpO2) changed after each session. Mean SpO2 before the three sessions of hemoperfusion was 89.60%±3.94% and increased to 92.13%±3.28% after them (p<0.001). Serum SERO IL-6 showed a reduction from 139.70±105.62 to 72.06±65.87 pg/mL (p=0.073); and c-reactive protein decreased from 136.25±84.39 to 78.25±38.67 mg/L (P=0.016).ConclusionsExtracorporeal hemoadsorption could improve the general condition in most of recruited patients with severe c oronavirus disease; MESHD however, large prospective multicenter trials in carefully selected patients are needed to definitely evaluate the efficacy of hemoperfusion in COVID-19 patients.Trial registrationThe research protocol has been registered in the website of Iranian Registry of Clinical Trials with the reference number IRCT20150704023055N2. 

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MeSH Disease
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Transmission
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