Objective: To evaluate aerosol-spread in cardiopulmonary resuscitation (CPR) using different methods of airway management. Knowledge about Aerosol spread is vital during the SARS-CoV-2-Pandemic. Methods: To evaluate feasibility we nebulized ultraviolet sensitive detergents into the artificial airway of a resuscitation dummy and performed CPR. The spread of the visualized aerosol was documented by a camera. In a second approach we applied nebulized detergents into human cadavers MESHD by an endotracheal tube and detected aerosol- spread during chest compressions the same way. We did recordings with undergoing compression- only-CPR, with a surgical mask and with an inserted laryngeal tube with and without a connected airway filter. Results: Most aerosol-spread at the direction of the provider was visualized during compression-only-CPR. The use of a surgical mask deflected the spread. Inserting a laryngeal tube connected to an airway filter lead to a remarkable reduction of aerosol-spread. Conclusion: The early insertion of a laryngeal tube connected to an airway filter before starting chest compression may be good for two Things: the treatment of hypoxemia HP as the likeliest cause of cardiac arrest HP and for staff protection during CPR.