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MeSH Disease

Human Phenotype

Transmission

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Seroprevalence
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    COVID-19 is a risk factor for severe liver damage MESHD for patients with intrahepatic cholestasis HP intrahepatic cholestasis MESHD of pregnancy: a case report

    Authors: Ling Ai; Jia Wei; Shaofang Wang; Xi Tan; Li Yan; Shangkun Liu; Liu Yang; Ailin Luo; Hui Xu

    doi:10.21203/rs.3.rs-26348/v1 Date: 2020-05-01 Source: ResearchSquare

    Background: Patients with intrahepatic cholestasis HP intrahepatic cholestasis MESHD of pregnancy (ICP) may present with slight liver damage MESHD. In the global outbreak, the number of pregnant women infected with coronavirus disease MESHD 2019 (COVID-19) is increasing. For the pregnant patients with ICP, COVID-19 may cause severe liver damage MESHD.Case presentation: A 31-year-old pregnant woman was admitted with fever HP fever MESHD and respiratory symptoms to Tongji Hospital in Wuhan amid the outbreak of COVID-19. Her chest CT scan showed an infection MESHD with viral pneumonia HP pneumonia MESHD as multiple ground glass opacities in both lungs were spotted. Laboratory tests revealed increased white blood SERO cell (WBC) count and decreased lymphocyte count. The levels of serum SERO total bile acid (TBA) were highly elvated. So were the indices of liver function, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), direct bilirubin (DBIL), alkaline phosphatase (AKP), 𝛄-glutamyltranspeptidase (𝛄-GT), and lactate dehydrogenase (LDH). The patient was later diagnosed of COVID-19 with comorbid ICP, presenting severe li ver damage. MESHDThrough timely termination of pregnancy and effective treatments, the prognoses of the patient and the fetus were well improved.Conclusions: This case highlights that COVID-19 may be a risk factor of severe li ver damage f MESHDor patients with ICP.Timely termination of pregnancy and effective symptomatic treatments are helpful to improve the progonosis.

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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